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S. Garte CSR Study Section Conformity Index (SSCI) using the QVR LIKE Function.

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Presentation on theme: "S. Garte CSR Study Section Conformity Index (SSCI) using the QVR LIKE Function."— Presentation transcript:

1 S. Garte CSR Study Section Conformity Index (SSCI) using the QVR LIKE Function

2 How well do study section members react to non conforming science outside the standard concepts and approaches in their fields? The question of conformity vs. innovation in NIH peer review has been raised in the scientific and popular press. The Issue

3 Compute a QVR fingerprint in for all applications submitted to each study section from 2007 to (146 SRGs) Using QVR LIKE function, determine the Match Score (MS) for each application. Applications with higher match scores are more conforming to the standard applications Methodological Approach

4 APPLICATIONMATCH SCORECOUNCILSTATUS 1 R01 CA A Withdrawn 1 R01 CA Withdrawn 2 R01 CA A Withdrawn 1 R01 CA A Pending Award 1 R01 CA Not Discussed 1 R01 CA Withdrawn 1 R01 CA Withdrawn 1 R01 CA Withdrawn 2 R01 GM A Awarded 1 R01 CA A Withdrawn 1 R01 CA Withdrawn Example of Match Score Data

5 TWO INDEPENDENT ASSESSMENTS 1. Compare average match score for all awarded grants to all non awarded applications (t test) 2. Percentage of applications awarded in the top match score quartile compared to the lowest quartile. (Chi square) Analytical Methods

6 Examples of No Significant Differences between Quartiles.

7 PERCENT OF STUDY SECTIONS WITH POSITIVE CONFORMITY INDEX (SSCI) # SRGs (AVMS) (Quart.)(Both) (Either) CSR DABP DBIB DNDA DPPS DTCS

8 Positive Correlation between SSCI and Bibliometric Measure of Quality (p < 0.001)

9 The great majority (90%) of CSR Study Sections do not penalize applications that do not conform The basic science SRGs tend to be more conformist than translational or clinical SRGs There is a correlation between conformity and bibliometric measure of quality. Summary and Conclusions

10 QUESTIONS?

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13 No Correlation with Application Number

14 No Correlation with Average Match Score

15 No Correlation with Range of Match Scores

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