Presentation on theme: "Sérgio Kwitko, Tiago Lansini, Andressa P Stolz, Diane R Marinho Authors have no financial interest in the subject matter of this poster."— Presentation transcript:
Sérgio Kwitko, Tiago Lansini, Andressa P Stolz, Diane R Marinho Authors have no financial interest in the subject matter of this poster
In cases of multiple corneal transplants, each new corneal graft increases the risks of rejection and complications such as glaucoma and macular edema, while the average time of graft survival decreases. Ma JJK, Graney JM, Dohlman CH. Repeat penetrating keratoplasty versus the Boston keratoprosthesis in graft failure. Int Ophthalmol Clin [Internet]. 2005 Jan [cited 2015 Jan 2];45(4):49–59. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16199966 The Kpro has been an important alternative in cases of corneal blindness in which penetrating corneal transplantation does not have a good prognosis. Aquavella J V, Qian Y, McCormick GJ, Palakuru JR. Keratoprosthesis: the Dohlman- Doane device. Am J Ophthalmol [Internet]. 2005 Dec [cited 2015 Jan 2];140(6):1032– 8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16376647 The purpose of our study was to evaluate the outcomes and complications of the Boston KPro in a retrospective case series from a single center, who all received similar surgical treatment and KPro technology.
A retrospective case series was performed on all patients undergoing Boston KPro implantation at Hospital de Clinicas de Porto Alegre performed between September 2005 and August 2014. A minimum follow-up of 6 months was required. Using a computerized patient database, 35 eyes of 29 patients were identified that met these criteria. Boston KPro implantation was performed via the standard technique. Dohlman CH, Abad JC, Dudenhoefer EJ et al. Ophthalmic Surgery: principles and practice. 3rd ed. Philadelphia, PA: W. B. Saunders; 2002.
Patients were examined postoperatively on the first day, first week, 2 weeks, and first month after surgery. If stable, the patients were followed every month. Best-corrected visual acuity (BCVA), complications and retention time of KPro were evaluated during the follow-up period.
Patients Thirty-five eyes of 29 patients were studied. No patients were lost to follow-up before 6 months. Mean follow up was 56.13 months (6 to 96 months). The Boston KPro was implanted in 20 right eyes and 15 left eyes. There were 13 females and 22 males. There were no significant differences on eyes involved or sex. Mean patient age at the time of KPro implantation was 47 years-old (range, 13 to 81 years-old SD=48,08) for all patients;
In conclusion, our cases series suggests that the KPro is a promising alternative for high risk PKP patients, and seems to be a viable option specially in cases of alkali burn and multiple previous PKP failures. One main advantage of the Boston KPro is no need of systemic immunosuppression. However, vision-threatening complications continue to be a major problem of this procedure, specially in a long-term follow-up.