The problem is you dont know the secrets of PubMed ("Atrial Fibrillation"[Mesh] OR "Atrial Flutter"[Mesh] OR ((atrial OR auricular) AND (fibrillation* OR flutter*)) OR AF[Text Word]) AND ("Factor Xa/antagonists AND inhibitors"[Mesh] OR ((factor xa OR factors 10a OR fXa OR autoprothrombin c OR thrombokinase) AND inhibit[Text Word]) OR (activated AND (factor x OR factors 10) AND inhibitor*) OR xabans[Text Word] OR (antistasin OR apixaban OR betrixaban OR du 176b OR eribaxaban OR fondaparinux OR idraparinux OR otamixaban OR razaxaban OR rivaroxaban OR aygin OR ym 150 OR ym150 OR LY517717 OR darexaban OR edoxaban OR SSR126517E) OR ((dabigatran OR BIBR1048) OR ximelagatran OR AZD0837))
Oooops…..but you can search “systematic reviews” [best evidence]
8 systematic reviews for my question Wake up!!! You have to read them, compare which studies they include ….and beg they are well conducted, say the same thing and address the same studies. Out of bed, sleepyhead!!!
The challenge: to separate the wheat from the chaff 23,000,000 records only in PubMed 0,25% are systematic reviews
Our goal TO AGGREGATE ALL THE RELEVANT HEALTH EVIDENCE (FOR DECISION-MAKING) INTO A SINGLE DATABASE.
Multilingual interface Multilingual search Translations of abstracts
What evidence? Systematic reviews Overviews of reviews High-quality structured summaries Primary studies included in systematic reviews
Systematic reviews (SR) at the centre The average SR takes about 1-year of work We rescue that effort by storing identified studies From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centrehttp://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html