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Today’s Agenda w Objective notes w Practice w Objective notes
Immune System Day 6 A single event can awaken within us a stranger totally unknown to us. Saint-Exupery
Antibodies w 2 heavy chains (450 amino acids) w 2 light chains (220 amino acids w Connected by a (S-S) disulfide bridge. w The whole protein has 1340 amino acids.
Objective 14 wAwActive immunity is acquired during an infection or from a vaccination.
Obj.14 continued wPwPassive immunity is given when a donor’s antibodies are injected into the blood- stream or from mother.
Obj Classes of Antibodies w IgA (immunoglobulin A) w IgG (these all differ by w IgM structure and function) w IgD w IgE
Obj. 16 Function of Antibodies w Complement fixation w Antigen neutralization w Precipitation w Agglutination
Neutralization by Antibodies
Agglutination by Antibodies
Precipitation of Dissolved Antigens by Antibodies
Activation of Complement By Antibodies
Objective 17: Clonal Selection of T cells w T cell growth is stimulated by the protein displayed on the surface of the macrophage. w Some become active killers others become memory T cells.
Obj. 18: Roll of T Cells w Cytotoxic T cells attack and lyse infected cells. w Helper T cells release interleukin. w Suppressor T stop immune response
View Video Clip Laser Disk 11
Specific Defense Mechanisms – The Immune System. The Immune System – 3 rd Line of Defense Antigen specific – recognizes and acts against particular.
IMMUNITY. What is Immunity? Ability of the body to protect itself from viruses, bacteria, and other disease causing agents The word immunity comes from.
Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.
Chapter 17 Immune response. Two types of resistance. Innate resistance and acquired resistance. Innate resistance – one is born with the resistance. All.
Non-specific defense mechanisms 1st line- skin and mucous –Cilia lined trachea, hairs in pathways 2nd line- –phagocytic WBC –antimicrobial proteins (compliment.
u Proteins that recognize and bind to a particular antigen with very high specificity. u Made in response to exposure to the antigen. u Each antibody.
Adaptive immunity How can the immune system recognize so many different (previously unseen) insults? How does the immune system learn? How do B cells produce.
16-1 Antigens Immunogen – a molecule that specifically interacts with an antibody or lymphocyte and elicits an immune response Antigenic determinants (epitopes)
Highlights of Immune System. Topic Outline Overview of the Immune System 1 st and 2 nd lines of Defense The Immune System B cells The antibody & antibody.
The Immune System Ch th ed Campbell’s Biology.
Specific Immune Defense. Antigens Antibody-generator, Non-self, Large molecules Properties: ◦1. Immunogenicity ◦2. Reactivity Antigenic determinant or.
AP Biology s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s Structure of antibodies light chains antigen-binding site heavy chains.
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chapter 14 Specific Immunity (adaptive immunity)
ANTIBODIES def - protein molecules that combine specifically with antigens. Proteins with antibody activity are known as immunoglobins.
Chapter 43 The Body’s Defenses. Lines of Defense Nonspecific Defense Mechanisms……
Immune System Chapter 43 ~ The Body’s Defenses. Lines of Defense Nonspecific Defense Mechanisms……
Lecture #19Date _________ Chapter 43 ~ The Body’s Defenses.
Acquired Immunity Defends Against Infection of Body Cells and Fluids By: Jonah Harrington, Josh Yi.
THE IMMUNE SYSTEM LECTURER: DAVID.
Antibody-mediated Immunity Immunology Unit Department of Pathology College of Medicine, KSU.
Specific Defense The Adaptive Immune Response. Specific Immunity Augments mechanisms of nonspecific defense Has memory about specific pathogens Second.
Humoral Immune Response Terry Kotrla, MS, MT(ASCP)BB Fall 2006.
Lector Tvorko M. S.. ANTIBODIES (IMMUNOGLOBULINS) Antibodies are globulin proteins (immunoglobulins) that react specifically with the antigen that stimulated.
AP Biology Immune Systems Part 2. Important concepts from previous units: 1) Three parts to the Signal Transduction Pathway – Reception, transduction,
Chapter Pgs Objective: I can describe how adaptive immunity (immunological memory) works. Challenging but cool, like a Rube Goldberg.
Specific Defenses of the Host Adaptive or Specific Immunity.
Specific Immune Responses How the Immune System Handles Specific Antigens.
Antibody-mediated Immunity Dr. Hend Alotaibi Assistant Professor & Consultant College of Medicine, King Saud University Dermatology Department /KKUH.
The Body’s Defenses Ch. 43. While some organisms can live symbiotically within animals, there are MANY that cause harm Humans have a three level defense.
Pages Soluble proteins secreted by activated B cells or by their plasma- cell offspring (in response to an antigen) They are capable of binding.
Immunogenetics chapter 22 select topics pp
Chapter 43 ~ The Body’s Defenses. Lines of Defense Nonspecific Defense Mechanisms……
Chapter 43: The Immune System. Lymphocytes: Specialized White Blood Cells : Two Types: B Lymphocytes T Lymphocytes.
Specific Immunity. What is specific immunity? Third line of defense Pathogen specific Involves antigens and antibodies.
Specific Immunity Destroy specific antigens that invade the body.
General Microbiology (Micr300) Lecture 15 Adaptive Immunity (Text Chapter: )
Immune system Chapter 43. Pathogen: Infectious agent Innate immunity: Nonspecific Acquired immunity: Specific Previous exposure.
Human Anatomy and Physiology Immunology: Adaptive defenses.
MHC Molecules Our immune system has the remarkable ability, and responsibility, of responding appropriately to a wide variety of potential pathogens in.
Immune System. Non-Specific Immunity Lysozyme – digests cell walls Skin (physical barrier) Stomache Acidity Phagocytes (roam body for bacteria/dead cells)
Antibody structure Heavy chain constant region determines antibody class.
The Immune System Chapter 43 Biology – Campbell Reece.
BCM 410A lecture 35 immunity immunoglobulin structure antibody classes monoclonal antibodies immunity immunoglobulin structure antibody classes monoclonal.
NOTES: Specific Defenses / Immunity (UNIT 9 part 3)
Immunity Innate and Adaptive Immunity Cells of the Immune System Physical & Chemical Barriers.
Immune system Chapter 43. Figure 43.1 Pathogen: Infectious agent Innate immunity: Nonspecific All animals Acquired immunity: Specific Previous exposure.
Adaptive Immunity: Specific Defenses of the host Ch 17.
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