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Ever since Camillo Golgi first described the "Apparato reticolare interna" (Golgi, 1898), this organelle has been studied intensively (reviewed by Berger, 1997).
Proteins can be Glycosylated
N-linked And O-linked on Ser and Thr residues
Glycosylation can be regulatory
Extracellular Matrix contains Sugars and Proteins GAG Glycosaminoglycans Unbranched repeating disaccharide chains Hydrated, gel-like ground substance Typically 70-200 sugars long SO 3 Most negatively charged (anionic) molecules produced by animal cells
Yano, Hiroyuki et al. (2005) Proc. Natl. Acad. Sci. USA 102, 13467-13472 Furthermore, during mitosis, the Golgi cisternae of mammalian cells become fragmented without their disassembly (2, 3). In Drosophila, Golgi cisternae are stacked but are not connected to form a ribbon at the embryonic and pupal stages even during interphase (4, 5), although there has been no evidence to date to indicate functional differences among the Golgi fragments.
Notch signaling is involved in founder cell determination in the visceral mesoderm. Fas3 Mouse anti-Fas3 Cy3 goat anti-mouse secondary The visceral mesoderm is visualized by Fas3 in Drosophila embryos (Holtz) Immunolocalization: