How a DNA strand is written 5’ - ATAGGGCCTAGAACCTGG - 3’ 3’ - TATCCCGGATCTTGGACC - 5’ Strands are anti-parallel
Try writing one yourself 3’ - TTAAGCTATGCT - 5’ What is the complementary DNA strand?
Now draw a double strand, including bases and backbones 5’ - ATGC - 3’ 1.Does your diagram have sugars, phosphates, and nitrogen bases? 2.Are the strands anti-parallel? 3.Where are covalent bonds between nucleotides? 4.Where are the hydrogen bonds?
Genes A gene is a specific sequence of DNA nucleotides The DNA sequence contains the information necessary to build a protein Each specific gene codes for a specific protein
How much DNA is there? The human genome contains 3 billion base pairs of DNA, about the same amount as frogs and sharks. But other genomes are much larger. A newt genome has about 15 billion base pairs of DNA, and a lily genome has almost 100 billion.
Unravel all the DNA in your body… …and it would stretch to the moon!
Junk DNA Only a very small percentage of your DNA (1.5%) is actually composed of coding genes, most of it is repetitive sequences or other non-coding sequences We still don’t know what the other 98.5% of DNA in our cells are for. We’ve still got a whole lot to learn
DNA structure This is known as the 5 I (five prime) carbon 2:001:591:581:571:561:551:541:531:521:511:501:491:481:471:461:451:441:431:421:411:401:391:381:371:361:351:341:331:321:311:301:291:281:271:261:251:241:231:221:211:201:191:181:171:161:151:141:131:12