PUTRESCINE CADAVERINE H 2 N – CH 2 – CH 2 – CH 2 – CH 2 – NH 2 H 2 N – CH 2 – CH 2 – CH 2 – CH 2 – CH 2 – NH 2 CHOLERA BACTERIUM (1,4-diaminobutane or butanediamine) (1,5-diaminopentane or pentanediamine)
are produced by the breakdown of amino acids in living and dead organisms and both are toxic in large doses. two compounds are largely responsible for the foul odor of putrefying flesh, but also contribute to the odor of such processes as bad breath and bacterial vaginosis. also found in semen and some microalgae, together with related molecules like spermine and spermidine. PUTRESCINE & CADAVERINE
SPERMINE H 2 N – (CH 2 ) 4 – NH – (CH 2 ) 3 – NH 2 SPERMIDINE H 2 N – (CH 2 ) 3 – NH – (CH 2 ) 4 – NH – (CH 2 ) 3 – NH 2 First isolated from human seminal fluid, were they are highly concentrated
Amines are organic compounds and a type of functional group that contain nitrogen as the key atom. Structurally amines resemble ammonia, wherein one or more hydrogen atoms are replaced by organic substituents such as alkyl and aryl groups. Amines are central in organic chemistry. All known life processes depend on AMINO ACIDS, each of which contains an amine group.
The nomenclature of amines is complicated by the fact that several different nomenclature systems exist, and there is no clear preference for one over the others. The most important thing to remember is when to use the following : 1. amine 2. amino 3. aniline
SIMPLE AMINES - can be named by common nomenclature as ALKYLAMINE in which amine is added to the name of the organic group. IUPAC NAMING – Is done by dropping the – e – of the alkane parent chain then add AMINE.
To name a substituted amine, both the name and the location of the substituent must be identified. Substituent on a carbon chain are located by a number, whereas those on a nitrogen are identified by a capital italic letter – N –.
AMINE AS SUBSTITUENT NH 2 – functional group is treated as a chain substituent we called them as amino group and the amine is named as a derivative of the parent compound following the IUPAC rules.
AROMATIC AMINES Are usually given names (both common & IUPAC name) based on aniline, the simplest aromatic amine. Substituted anilines are named using an italic capital – N – to indicate the attached alkyl group to NITROGEN. Substituents attached to aromatic ring are named based on the usual way we name them.
Low Molecular Weight AMINES are gases at room temperature that possess a characteristic ammonia smell. Complex Molecular Weight AMINES are either liquid or solid at room temperature having a distinctive "fishy" or extremely foul decomposing smell. Primary & Secondary amines are usually exhibit lower boiling points compare to tertiary and more complex structure amines. Amines with fewer than six carbon atoms are generally soluble in water as the result of hydrogen bond formation between amine functional group and water.