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Cutaneous ciliated cyst (Cutaneous Mullerian cyst) Deba P Sarma, MD Omaha.

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Presentation on theme: "Cutaneous ciliated cyst (Cutaneous Mullerian cyst) Deba P Sarma, MD Omaha."— Presentation transcript:

1 Cutaneous ciliated cyst (Cutaneous Mullerian cyst) Deba P Sarma, MD Omaha

2 F 48, right heel Cyst in the soft tissue

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5 Note the cilia on the luminal border of the columnar epithelium

6 Pan-CK (CK AE 1/3): Positive cytoplasmic stain

7 Cam 5.2 (CK8/18): Positive cytoplasmic stain

8 CEA: Negative

9 ER: Positive nuclear stain

10 PR: Positve nuclear stain

11 Diagnosis: Soft tissue, right heel, excisional biopsy: - Cutaneous ciliated cyst - (Cutaneous Mullerian cyst)

12 Cutaneous ciliated cyst (Cutaneous Mullerian cyst) -Solitary cystic lesion of lower limb of woman (10-50 yrs). -Thought to be arising from heterotopic Mullerian epithelium. -Cyst is unilocular or multilocular with intralocular papillary projections, lined by ciliated cuboidal or columnar epithelium similar to that of fallopian tube. -Lining cells show immmunoprofile similar to that of fallopian tube epithelium (Positive cytoplasmic staining with CK, Negative CEA, and Positive nuclear staining with ER and PR). -Rare ciliated cutaneous cysts seen in man are thought to be arising from eccrine or apocrine gland with cilia metaplasia. -Differential diagnosis: Ciliated epithelial cells are also seen in brochogenic, thyroglossal duct, branchial, thymic and mature cystic Teratoma.

13 REF: Stevens T, Sarma DP.(2011). Biopsy of a 5 mm cystic lesion on the right heel of a 48-year-old woman. Dermatol Online J. 15(17):6. PMID: [PubMed – indexed for MEDLINE] Stevens T, Sarma DP.(2011). Biopsy of a 5 mm cystic lesion on the right heel of a 48-year-old woman. Dermatol Online J. 15(17):6. PMID: [PubMed – indexed for MEDLINE]


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