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Microfluidics Mixing Chamber.

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Presentation on theme: "Microfluidics Mixing Chamber."— Presentation transcript:

1 Microfluidics Mixing Chamber

2 Where? / With Whom? Intro to Project Proposal How?

3 Micro-Fabrication Facility (MFF)
Dr. Michael Khbeis Kristopher Lawler Andy Lingley Class cleanroom -> Class 100 11,500 sq ft of wet & dry lab space Photolithography Nanolithography Dry Etch PVD CVD Thermal processing Metrology

4 How is microfluidic mixing different?
[5] Turbulent Laminar

5 Reynolds Number[2] Re = (ρ * V * L) / mu Dimensionless measure of the ratio of inertia force to viscous force Inertial forces = density (ρ) * velocity (V) * gradient of the velocity (dV/dx) Viscous forces = dynamic viscosity coefficient (μ) * second gradient of the velocity (d2V/dx2) High Reynolds numbers - turbulent mixing Low Reynolds numbers - mixing relies on diffusion 0.1 = (1000kg/m3 * m * 0.001m/s) [1] 0.001Ns/m2

6 Passive Microfluidic Mixers[1]
Lamination Intersecting Channels Zigzag Channels Three-Dimensional Serpentine Structures Embedded Barriers Slanted Wells Surface-Chemistry Technology in Microchannels

7 Laminar mixing [1] Diffusion limited Takes time and distance

8 Intersecting and Zigzag Channels
[1] [1]

9 Three-Dimensional Serpentine Structures and Grooves

10 Embedded Barriers [4]

11 Hong Chamber [6]

12 Questions?

13 [7]


15 Works Cited Lee CY, Chang CL, Wang YN, Fu LM (2011) Microfluidic mixing: a review. Int J Mol Sci 12: 3263–3287. Benson, Tom. "Reynolds Number." Reynolds Number., 22 May Web. 18 Apr <>. De Buryn Kops, Steve, and Jim Riley. "Turbulent Mixing." EFluids Gallery Image and Description., n.d. Web. 18 Apr <>. "Injection Molding Static Mixing Nozzle (Type SMN)." - StaMixCo Polymer Melt Viscous Processing Static Mixer Products & Technology., n.d. Web. 18 Apr <>. "Mass Transport · Teaching Notes." Department of Chemical Engineering and Biotechnology. University of Cambridge, Web. 18 Apr <>. "Microfluidic CFD Applications: Multiphase Mixing and Bubble Dynamics." Microfluidics Applications: Simulating Multiphase Mixing. Flow Science, n.d. Web. 19 Apr <>. Applied Physical Sciences - Chemistry: Andres W. Martinez, Scott T. Phillips, and George M. Whitesides Three-dimensional microfluidic devices fabricated in layered paper and tape PNAS (50) ; published ahead of print December 8, 2008, doi: /pnas

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