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Microfluidics Mixing Chamber. 1.Where? / With Whom? 2.Intro to Project 3.Proposal 4.How?

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Presentation on theme: "Microfluidics Mixing Chamber. 1.Where? / With Whom? 2.Intro to Project 3.Proposal 4.How?"— Presentation transcript:

1 Microfluidics Mixing Chamber

2 1.Where? / With Whom? 2.Intro to Project 3.Proposal 4.How?

3 Micro-Fabrication Facility (MFF) Dr. Michael Khbeis Kristopher Lawler Andy Lingley Class cleanroom -> Class ,500 sq ft of wet & dry lab space Photolithography Nanolithography Dry Etch PVD CVD Thermal processing Metrology

4 Turbulent Laminar How is microfluidic mixing different? [5]

5 Reynolds Number [2] Re = (ρ * V * L) / mu Dimensionless measure of the ratio of inertia force to viscous force Inertial forces = density (ρ) * velocity (V) * gradient of the velocity (dV/dx) Viscous forces = dynamic viscosity coefficient (μ) * second gradient of the velocity (d 2 V/dx 2 ) High Reynolds numbers - turbulent mixing Low Reynolds numbers - mixing relies on diffusion 0.1 = (1000kg/m 3 * m * 0.001m/s) [1] 0.001Ns/m 2

6 Passive Microfluidic Mixers [1] Lamination Intersecting Channels Zigzag Channels Three-Dimensional Serpentine Structures Embedded Barriers Slanted Wells Surface-Chemistry Technology in Microchannels

7 Laminar mixing Diffusion limited Takes time and distance [1]

8 Intersecting and Zigzag Channels [1]

9 Three-Dimensional Serpentine Structures and Grooves [1]

10 [4] Embedded Barriers

11 Hong Chamber [6]

12 Questions?

13 [7]


15 1.Lee CY, Chang CL, Wang YN, Fu LM (2011) Microfluidic mixing: a review. Int J Mol Sci 12: 3263– Benson, Tom. "Reynolds Number." Reynolds Number., 22 May Web. 18 Apr De Buryn Kops, Steve, and Jim Riley. "Turbulent Mixing." EFluids Gallery Image and Description., n.d. Web. 18 Apr "Injection Molding Static Mixing Nozzle (Type SMN)." - StaMixCo Polymer Melt Viscous Processing Static Mixer Products & Technology., n.d. Web. 18 Apr "Mass Transport · Teaching Notes." Department of Chemical Engineering and Biotechnology. University of Cambridge, Web. 18 Apr "Microfluidic CFD Applications: Multiphase Mixing and Bubble Dynamics." Microfluidics Applications: Simulating Multiphase Mixing. Flow Science, n.d. Web. 19 Apr Applied Physical Sciences - Chemistry: Andres W. Martinez, Scott T. Phillips, and George M. Whitesides Three-dimensional microfluidic devices fabricated in layered paper and tape PNAS (50) ; published ahead of print December 8, 2008, doi: /pnas Works Cited

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