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Published byBruno Lotts Modified about 1 year ago

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Introduction: Gravitational forces resulting from microgravity, take off and landing of spacecraft are experienced by individual cells in the living organism. Such stresses alter cell shape, cytoskeleton organization and internal pre-stresses in the cell tissue matrix. Spaceflight is associated with a significant increase in the number of circulating blood cells including leukocyte, B cells and T-helper cells and their motion through capillaries. Prior studies have shown that the stresses due to the spaceflight lead to a sympathetic nervous system-mediated redistribution of circulating leukocytes. In addition, study of the cell migration is relevant to several other biological processes such as embryogenesis, and cell division. Obtaining the properties of human blood cell is necessary to have a better understanding of the deformability of human cells, in particular the leukocytes, under various stress conditions such as those in a spaceflight and microgravity. Properties of a drop, surface tension and viscosity can be determined based on the dynamical behavior and shape deformation during motion through a nozzle. Numerical technique: Full Navier-stokes and continuity equations for an incompressible and Newtonian fluid are solved numerically. To solve the flow equations within the drop, the numerical model needs to track the location of the liquid interface. Interface Tracking model (Volume-Of-Fluid): For each cell a volumetric function f defined, representing the amount of the fluid present in that cell. The surface cells are defined as the cell with 0

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