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Research Retreat Current Overview Tom Hostetter Vice Chairman for Research.

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Presentation on theme: "Research Retreat Current Overview Tom Hostetter Vice Chairman for Research."— Presentation transcript:

1 Research Retreat Current Overview Tom Hostetter Vice Chairman for Research

2 Some Outcomes of Last Retreat 2009 Agre Society solidified Annual Research Day Distribution of CTSC resources Meeting with SOM and UH leaders regarding research issues

3 Research Award Costs ( $ millions) Year DOM SCC

4 Research Cost FederalState Foundatio nIndustryTotal CV Medicine 7,046,71002,515,4921,080,52310,642,725 Clinical Pharm 446, Endocrinology 1,175,71602,50049,0051,227,221 GI 3,635, ,0133,873,649 Gen Med 313, Geriatrics 70, Heme/Onc 4,574, ,040998,9736,354,106 ID/HIV/Medicine 23,857,151192,541636,169107,61124,793,472 Nephrology/Hyp 4,837, ,3024,907,906 Pulmonary/CC/Slee p 2,238, ,000260,4802,599,025 Rheumatology 00000

5 Sources of Awards ($ millions) FederalStateFoundationIndustry

6 Selected Highlights 2012 VAMC- Highly Funded Programs in Implementation, Quality and Education Research Basic and applied studies of antibiotic resistance GREC revitalized CV- High impact papers in Science and Nature 6 new RO1s and a DARPA grant Mukesh Jain elected VP of ASCI Endo- NIH trials ACCORDION,EDIC Studies in diabetic retinopathy GI- NIH funded Network for study of Barrett’s PPG for IBD Over 40 new or competing renewal grants, one half from NIH

7 Selected Highlights 2012 Heme/Onc- Cancer Center renewed High impact papers in NEJM, PLOS Genetics, JBC, PNAS ID- Progress in HIV and TB research Creation of ID and Immunology Institute Expansion of work in Uganda including CV Neuro, & Genetics Renal/Htn- Leadership in NIH SPRINT and CRIC trials Ongoing participation in NIH Clinical Trials in Organ Transplantation 2 endowed faculty positions from Centers for Dialysis Care

8 Underrepresented Areas Topics - Human/Population Genetics - Outcome/Health Care Delivery - Comparative Effectiveness Research - Geriatrics Grant Types - K grants - for early career - P and U grants – for multiple investigators - Industry

9 Threats to Funding NIH budget has been declining in constant dollars about 10 years ( ARRA funds in 2009 and 2010 excepted) Sequestration of 5- 10% of NIH budget will lead to about 2500 fewer new grants funded

10 FASEB

11 Responses To Funding Threats Industry support- now about 6 % of total

12 Responses To Funding Threats Industry support Philanthropy Examples: Harrington Discovery Institute Centers for Dialysis Care

13 Responses To Funding Threats Industry support Philanthropy Widen range of Federal Sources CTSC cores and pilot grants AHRQ DOD PCORI

14 Patient Centered Outcomes Institute (PCORI) Part of the Affordable Care Act 2013 Budget $390 million PCORI approved 25 awards, totaling $40.7 million over three years, to fund patient-centered comparative clinical effectiveness research projects

15 PCORI’s Research Budget Distribution

16 Responses To Funding Threats Industry support Philanthropy Widen range of Federal Sources CTSC cores and pilot grants AHRQ DOD PCORI Better grants to Traditional Federal Sources Multi PI / Team Collaboration with other departments / institutions

17 Training Med Students Theses Residency short track Grad Students Tuitions F, T and K NIH Grants

18 Medical Student Theses Students are required to write a thesis. They have 4 months of committed time and an optional summer block after 1 st year. About 8% work in the DOM for their theses To let students know of your research, update your info on the ePortfolio site. https://casemed.case.edu/ePortfolioFaculty08/ Also send to Todd Fennimore, Director of the Office of Medical Student Research,

19 Arrive at CWRU School of Medicine Year 1Year 2 Year 3Year 4 Begin investigating areas of research interest Contact potential mentors for the summer with the idea of a project that leads into the research block in year 3. Decide on a mentor for the summer and submit IRB applications & funding applications. Medical Student Research Timeline SUMMER RESEARCH Schedule Yr 3 including the research block Submit the research proposal and submit IRB application 4 mo. Research progress reports due at 1 and 2 month points Research summary due the Friday after the end of the research block Work on M.D. thesis M.D. thesis due by January 15 th of the 4 th year Lepow Medical Student Research Day RESEARCH BLOCK Lepow Medical Student Research Day

20 29% 48% The value of a research continuum including the summer between years 1 & 2 as well as the research block in year 3. Courtesy of Jim Bruzik Percent of Published Student Research

21 Training Med Students Theses Residency Short Track Grad Students Tuitions F, T and K NIH Grants

22 Graduate Student Support by DOM Selected PhD students enrolled in SOM with a DOM PI DOM will pay their tuition PI must pay their stipend from grant, etc and division guarantee support for the term of the student’s course. About 20 students are being supported

23 Break Outs Breakout #1: Evolving NIH/Federal Funding Landscape Leaders: Richard Walsh, MD & Fabio Cominelli, MD Breakout #2: Mentoring and Career Development Leaders: Mukesh Jain, MD & Aaron Proweller, MD Breakout #3: Team Science and Multidisciplinary Research Leaders: Amitabh Chak, MD, Stanton Gerson, MD & Robert Salata, MD Breakout #4: Enhancing Industry-sponsored Research Opportunities Leaders: Neal Meropol, MD, & Marco Costa, MD, PhD


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