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Membrane Transport III Chapter 11
Selectivity of a K + channel
DVD Clip 45
DVD clip 48
Patch Clamp Recording
Patch Clamp Measurements of single voltage gated Na + channel 3 experiments on the same patch cumulative of 144 experiments
Resting Chemical Synapse
Active Chemical Synapse
Neuromuscular Junction in a Frog
Three Conformations of Acetyl Choline receptor at the neuromuscular junction
DVD Clip 49
Ion Channels at Neuromuscular Junction
Motor Neuron Cell body in the Spinal Chord
thousands of axon terminals are stained red by antibody that recognizes a protein in synaptic vesicles
Chapter 12 Intracellular Compartments and Protein Sorting
Major Intracellular compartments of an animal cell
Volumes of major intracellular compartments in a liver cell
Relative amount of membrane types in 2 cell types
Complex Cortical Network of Endoplasmic Reticulum
Cross section of liver cell
Topological relationships between compartments of a eukaryotic cell
Roadmap of protein traffic inside cell
Two ways in which a sorting signal can be built into a protein
Some typical signal sequences
Nuclear Pore complexes perforate the nuclear envelope
Nuclear pore complexes
Nuclear side of the nuclear envelope
Face on view of nuclear complexes without the membrane
Side view of 2 nuclear pore complexes
Transport through nuclear pore complexes occurs through free diffusion and active transport
Nuclear import signal direst proteins to the nucleus
Single amino acid mutation in signal will prevent import into the nucleus
Nuclear import receptors bind to nuclear porins and nuclear localization signal of cargo protein Different nuclear localization signals bind different import receptors
Ran GTP provides energy for nuclear protein import
Ran-GTP controls cargo loading and unloading
Membrane Transport Chapter 11. Transcellular transport of glucose.
Roadmap of protein traffic inside cell. Two ways in which a sorting signal can be built into a protein.
Intracellular Compartments and Protein Sorting Compartmentalization of Cells Pages
Last Class: 1. Posttranscription regulation 2. Translation regulation 3. Cell membrane, phospholipids, cholesterol 4. Membrane protein, mobility, FRAP,
Chapter 8 Intracellular Compartments and Protein Sorting: Transport Between the Nucleus and the Cytosol Chapter 8 Intracellular Compartments and Protein.
Nervous System Chapter Structure of the Neuron Neurons come in all shapes & sizes Have common features Axon terminals Myelin sheath Nodes Cell body.
Nervous System Objectives of :State that the nervous system consists of the central nervous system (CNS) and peripheral nerves,
Review For Final I. Should I take the final? Can’t hurt you Calculate your average and determine what you need to change your grade.
Lecture 6 - Intracellular compartments and transport I.
Part 1: Intracellular trafficking Week 1: Transport through the nuclear pore complex Week 2: RNA transport, maturation & localization Week 3: ER translocation.
Neuron Structure and Function. Nervous System Nervous system is composed of specialized cells called neurons. Neurons have long “arms” called axons.
HOW NERVE CELLS COMMUNICATE! PACKET #19 CHAPTER #48—CAMPBELL Synaptic Signaling & The Action Potential.
Active Transport Section 4-2. Some substances are transported against a concentration gradient. Facilitated diffusion moves sugars and amino acids across.
SEHS Topic 4.1 Neuromuscular Function. Label a diagram of a motor unit Foundation required: A motor unit is made up of a motor neuron and all of the skeletal.
Structures and Processes of the Nervous System – Part 2 Section 8.2.
Nervous systems. Keywords (reading p ) Nervous system functions Structure of a neuron Sensory, motor, inter- neurons Membrane potential Sodium.
Neural communication How do neurons send messages to each other?
THE NERVOUS SYSTEM 35-2 BIO 1004 Flora. NERVOUS SYSTEM Nervous system – controls and coordinates functions throughout the body and responds to internal.
Cell Communication II Chapter 15. An animal cell depends on extracellular signals to survive or divide.
AH BIOLOGY: CELLS AND PROTEINS- PPT 6 MEMBRANE PROTEINS: CHANNEL AND TRANSPORT PROTEINS.
Myelin again Myelin speeds up the nerve impulse because nerve fibers have Schwann cells around them – Schwann cells restrict ion movement – So impulse.
Intracellular Compartments and Protein Sorting Haixu Tang School of Informatics.
Chapter 49 Table of Contents Section 1 Neurons and Nerve Impulses.
Section 33.1: Structure of the Nervous System. A. Neurons Neurons specialized cells that help you gather info about your environment, interpret the.
End Show Slide 1 of 38 Copyright Pearson Prentice Hall 35-2 The Nervous System.
Synapses. C. Action potential reaches the end of a presynaptic neuron. F. Voltage gated calcium channels open D. Calcium ions flow into the presynaptic.
Nervous System Ch 28, Sections Which type of immune response is always disadvantageous to a person? A) cell-mediated B) inflammatory C) humoral-mediated.
Chapter 4 Cells and Their Environment Section 1: Passive Transport Section 2: Active Transport.
NERVOUS TISSUE Chapter 44. What Cells Are Unique to the Nervous System? Nervous systems have two categories of cells: Neurons generate and propagate electrical.
The Neuron An everyday (every second!) use of active transport.
Nerve Supply to a Muscle. Nerve Supply Motor Neuron: Nerve that stimulates a muscle cell. A single nerve (motor neuron) will supply approximately 150.
Topic Nerves Overview of the Nervous System Three major functions: Sensory input – sensory receptors receive signal – peripheral nervous.
Membrane transport: The set of transport proteins in the plasma membrane, or in the membrane of an intracellular organelle, determines exactly what solutes.
Nervous Systems Three Main Functions: 1. Sensory Input 2. Integration 3. Motor Output.
Membrane Transport1 Not responsible for: Nernst Equation, other than to know what it’s used for. Chapter 12 Membrane Transport Questions in this chapter.
Chapter 49 The Neuromuscular Junction and Muscle Contraction 1.
Dopamine (DA) neuron Cell body (Soma) terminals axons Dendrites.
The Nervous System Neuron –Cell body; Dendrites; Axon Three general groups of neurons –Sensory neurons (afferent or receptor) Receive the initial stimulus.
Chapter 28 Nervous system. NERVOUS SYSTEM STRUCTURE AND FUNCTION © 2012 Pearson Education, Inc.
Chapter 4 Cells and Their Environment. Section 1: Passive Transport Cell need to maintain Homeostasis Controlling what moves across the cell membrane.
Figure 48.1 Overview of a vertebrate nervous system.
Learning Target: Neurons Basic Unit of the Nervous System.
Neurons- The matter of the nervous system Chapter 7: Pgs
Nerve Supply to Skeletal Muscle. Nerve Supply The outside of the nerve plasma membranes contain a slightly positive charge (Na+). The inside of this same.
Chapter 8b Neurons: Cellular and Network Properties.
Functions of Neurons Resting & Action Potential Synapses.
Chapter 34 Opener Chapter 34: Neurons and The Nervous System.
Afferent Nerves Efferent Nerves cell body: cell body: central part of cell; contains the nucleus axon: axon: long slender extension from cell body; used.
Neurons & Neuroanatomy What are the characteristics of neurons important for Cognitive Neuroscience? What is the brain structure important for CogNeuro?
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