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Final Code Tree Pneumoperitoneum or Free Intraperitoneal Air Y N IIIBAscites or Portal Venous Gas YN Ventilator or Vassopressors or Neutropenia at Day.

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Presentation on theme: "Final Code Tree Pneumoperitoneum or Free Intraperitoneal Air Y N IIIBAscites or Portal Venous Gas YN Ventilator or Vassopressors or Neutropenia at Day."— Presentation transcript:

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2 Final Code Tree Pneumoperitoneum or Free Intraperitoneal Air Y N IIIBAscites or Portal Venous Gas YN Ventilator or Vassopressors or Neutropenia at Day of Dx YN IIIA IIB Pneumatosis Intestinalis or Thicken bowel wall or Air/fluid levels YN IIA Grossly Bloody Stool YN IBIA

3 Training N=429 Testing N=158 Staging s Score @ Diagnosis

4 Training N=429 Testing N=158

5 LD1 1 freeipair 2.2000022019 2 pneumo 1.4023280789 3 portvenous 1.3417965936 phval -1.2116904385 venton 0.6258134537 feedintol 0.5587447893 abdcolor 0.5046600489 abddistend 0.3848253781 abdileus -0.3783655073 thickbowel -0.3742092256 air 0.2852206988 pintestin 0.1950671434 phsite -0.1793325231 dilatebowel -0.1766555924 caprefill -0.1676547616 thrombocyto 0.1669202262 bloodstool 0.1589296601 abdpain 0.1007602275 o2desat 0.0806709600 neutropenia 0.0463782983 neutcount 0.0378945014 apneic 0.0318267688 wbccell -0.0301628294 bandsperc 0.0190156007 bicarb -0.0103911553 acidosis 0.0062104076 vasson -0.0039799850 neutperc 0.0029960484 platcount -0.0003824272

6 NEC score Density NEC S NEC M TrainingTesting Training Testing ROC AUC 0.906 0.892 False positive rate True positive rate AB

7 M S N = 3 N = 65 N = 2 N = 28 M S N = 135 N = 7 N = 36 N = 3 Training Testing Patient ID after sorting by NEC score NEC score M S N = 120 N = 65 N = 49 N = 37 NEC

8 # of clinical parameters ROC AUC Training Testing

9 # of clinical parameters ROC AUC Training Testing

10 NEC score Density NEC S NEC M TrainingTesting Training Testing ROC AUC 0.879 0.898 False positive rate True positive rate AB

11 M S N = 3 N = 69 N = 2 N = 32 M S N = 67 N = 3 N = 26 N = 2 Training Testing Patient ID after sorting by NEC score NEC score M S N = 188 N = 65 N = 59 N = 34 NEC

12 # of clinical parameters ROC AUC Training Testing

13 NEC score Density NEC S NEC M TrainingTesting Training Testing ROC AUC 0.871 0.913 False positive rate True positive rate AB

14 M S N = 3 N = 68 N = 2 N = 26 M S N = 42 N = 2 N = 20 N = 0 Training Testing Patient ID after sorting by NEC score NEC score M S N = 213 N = 67 N = 65 N = 42 NEC

15 # of clinical parameters ROC AUC Training Testing

16 NEC score Density NEC S NEC M TrainingTesting Training Testing ROC AUC 0.826 0.912 False positive rate True positive rate AB

17 M S N = 3 N = 61 N = 2 N = 31 M S N = 5 N = 0 N = 10 N = 0 Training Testing Patient ID after sorting by NEC score NEC score M S N = 250 N = 76 N = 75 N = 37 NEC

18 PAM algorithm for the selection of discriminating features for NEC M and S

19 LD1 phval -2.2055309424 portvenous 1.3076542171 abdcolor 0.8216953121 venton 0.6891401925 thickbowel -0.6109360776 abdileus -0.5729964064 dilatebowel -0.5152799841 feedintol 0.3770836348 neutropenia 0.3508775855 abddistend 0.2990016172 abdpain 0.2874041759 phsite -0.2781764664 caprefill -0.2621917372 acidosis -0.1458238909 vasson 0.0757143616 o2desat -0.0748033015 pintestin -0.0557930985 thrombocyto -0.0537699567 apneic 0.0470925295 neutcount 0.0305651695 bloodstool 0.0294566441 bicarb -0.0293781813 bandsperc 0.0260929163 wbccell -0.0154507234 neutperc 0.0062913956 air 0.0056508200 platcount -0.0006709353

20 # of clinical parameters ROC AUC Training Testing

21 NEC score Density NEC S NEC M TrainingTesting Training Testing ROC AUC 0.876 0.888 False positive rate True positive rate AB

22 M S N = 1 N = 20 N = 1 N = 12 M S N = 54 N = 2 N = 17 N = 0 Training Testing Patient ID after sorting by NEC score NEC score NEC M S N = 203 N = 115 N = 69 N = 56

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25 8910114567123 Clinical parameters - Log10 (Speaman Correlation P Value)

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28 Final Code Tree Pneumoperitoneum or Free Intraperitoneal Air Y N IIIBAscites or Portal Venous Gas YN Ventilator or Vassopressors or Neutropenia at Day of Dx YN IIIA IIB Pneumatosis Intestinalis or Thicken bowel wall or Air/fluid levels YN IIA Grossly Bloody Stool YN IBIA

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