1. Anatomy & Neurobiology ANA 812 Digestive System III: Liver, Gallbladder & Pancreas Bethany Cox Sarah Marks Joe Slusher Kara Stebbins

2. Anatomy & Neurobiology Slide #106 Liver- Pig 4x Portal Area Liver Lobule

3. Anatomy & Neurobiology Slide #106 Liver- Pig Central Vein 10x 40x Central Vein Cords of Hepatocytes Liver Sinusoids Binucleate Cell

4. Anatomy & Neurobiology Slide #106 Liver- Pig 4x 40x Portal Vein Hepatic Artery Lymphatic Vessel Bile Ductule

5. Anatomy & Neurobiology Slide #106 Liver- Pig-40X Portal Vein Lymphatic Bile Ductule Hepatic Artery

6. Anatomy & Neurobiology Slide #101 Liver- Human-4X -Note relative lack of connective tissue.

7. Anatomy & Neurobiology Slide #101 Liver- Human-10X Central Vein Liver Sinusoids Hepatocyte Cords Lipid Droplets

8. Anatomy & Neurobiology Slide #104 Liver- Mouse 4x 40x Portal Vein Bile Ductule Lymphatic Vessel

9. Anatomy & Neurobiology Liver: Von Kupffer cells-40X H&E stain (human, slide 101 ) Trypan blue stain with neutral red (monkey, slide 103 ) Large oval nuclei projecting into sinusoids Trypan blue phagocytized into granules

10. Anatomy & Neurobiology Liver: One Effect of Cirrhosis-40X Normal liver ( H&E stain, human, slide 101 ) Cirrhosis ( Masson’s trichome stain, human, slide 107) Vacuolated hepatocyte cytoplasm Bile canaliculi

11. Anatomy & Neurobiology Liver: Another Effect of Cirrhosis-4X Normal liver (H&E stain, human, slide 101) Cirrhosis (Masson’s trichome stain, human, slide 107) Blue-staining collagen (fewer hepatocytes, more CT)

12. Anatomy & Neurobiology Slide #178 – Pancreas and Suprarenal Gland – Monkey (Azan Stain) – 4X Pancreatic Islets of Langerhans (endocrine portion of the pancreas) Ducts –Intercalated –Intralobular –Interlobular

13. Anatomy & Neurobiology Slide #178 – Pancreas and Suprarenal Gland – Monkey (Azan Stain) – 40X Islet of Langerhans 4X

14. Anatomy & Neurobiology More secretory acinar divided into lobules Ducts –Intercalated (not seen at this power) –Intralobular –Interlobular Slide #178 – Pancreas and Suprarenal Gland – Monkey (Azan Stain) – 10X

15. Anatomy & Neurobiology Slide #104-Gallbladder and liver-10X Simple columnar eplithelium Lamina propria Smooth muscle layer Definitive mucosal folds Monkey, H&E stain

16. Anatomy & Neurobiology Slide #105-Gallbladder -10X Human specimen after death Extremely folded gallbladder mucosa seen here is typical of human gallbadder Human, H&E stain

17. Anatomy & Neurobiology Comparison of Slides #104/#105-10X Monkey, H&E stain Human, H&E stain