1. A comparison of overall health between Asian and Australians from European background: A west Australian study of Diet & Metabolic Syndrome Risk Factors In the name of God Majid Meshkini Supervisor: Dr Jaya Earnest

2. Context of the researcher Selected Graduated as Doctor of Medicine (MD) from IUMS, 1996, Tehran, Iran As a medical doctor (GP), 1996-2006 Co-ordinator of urban physicians, savojbolaq city Head of Health Centre, Shahriar city As a manager in medical education field, MoHME As a manager in health affairs, MoHME Technical advisor for health sector of MoHME

3. The Trend of Diseases: Communicable Non-Communicable Non-Communicable Diseases: (CVD & Diabetes) Burden Overall: –35 million deaths annually: 60% of all deaths, over the World (WHO, 2006) Prevalence of some Important Diseases & risk factors: –Over weight & Obesity, 1.6 Billion adults (WHO, 200) –Diabetes, 300 million in 2025, (WHO, 200) Introduction

5. Different definition of the MetS World Health Organization (WHO), 1999 European Group for the Study of Insulin Resistance (EGIR), 1999 Adult Treatment Panel III, model (ATPIII), 2001 International Diabetes Federation (IDF), 2005

9. Ethnicity effects on MetS Genetic and metabolic syndrome –Genetics is a powerful factor in the incidence of MetS’ components –Affects among of both different countries & various ethnic group on a society Impact of ethnicity on MetS components –Comparison between African population & Caucasians –Comparison between Caucasians & South Asians

10. Prevalence of The MetS in some countries & region Australia30.7 % China46.3% India31.6% Iran26.4% South Asia10-30 %

11. Gaps Lake of a basic study in Australia focused on ethnicity effect on the MetS Comparison the correlation between ethnicity & MetS’ component such as, dyslipidemia and endothelial dysfunction Lake of statistics regarding to the Middle East

12. Objectives To investigate the effects of ethnicity on the metabolic syndrome risk factors in overweight and obese subjects To explore the relationship between other relative components in metabolic syndrome and different ethnic groups

13. Study plan & methodology Cross sectional design 5 Ethnic group X 30 / group = 150 participants Measurements –Anthropometrical –Physical –Biochemical, by blood sampling –Food records, using a questionnaire

14. Five Ethnic Group Australian from European background Chinese Iranian/ Afghani Iraqi/ Arabian South Asian, (Indian, Bangladeshi, Sri Lanka)

15. Measurements Anthropometrical: –Height –Weight –BMI, Body Mass Index –Waist circumference Biophysical: –BP –Endothelial Dysfunction –Fat Distribution Food intake –Total intake energy –Macro nutrients Carbohydrate, Protein & Fat –Fibres Fruits & vegetables –Food items will be undertaken at the Curtin University, Centre for International Health and by questionnaire

16. Measurements Continue Will be done in the laboratory of the School of Biomedical Science Biochemical: –FBG (Fasting Blood Glucose) –Serum lipid (Including Triglyceride & Cholesterol) –Insulin –CRP (C-Reactive Protein) –PAI, (Plasminogen Activator Inhibitor) –Adinopectin

17. Significance Efforts to achieving an acceptable definition for MetS, specified for Ethnic differences Reliable criteria for relative diseases diagnosis Multicultural foundation countries, Particularly Australia

18. Some analysis that I hope to undertake Comparison the metabolic syndrome among the different ethnic groups Evaluate the correlation between Ethnicity & CRP among of metabolic syndrome Explore the relationship between Endothelial Dysfunction and Ethnicity Is there an association between food intake & ethnicity