Presentation is loading. Please wait.

Presentation is loading. Please wait.

{ Understanding the “Silent” Disease: Pancreatic Cancer Tara Woodard 1.

Similar presentations


Presentation on theme: "{ Understanding the “Silent” Disease: Pancreatic Cancer Tara Woodard 1."— Presentation transcript:

1 { Understanding the “Silent” Disease: Pancreatic Cancer Tara Woodard 1

2  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 2

3  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 3

4  1) Lung and bronchial cancer ( > 157,000 )  2) Colon and rectal cancer ( > 51,000 )  3) Breast cancer ( 40,000 )  4) Pancreatic cancer ( 37,000 )  5) Prostate cancer ( 32,000 ) Top 5 Deadliest Cancers: 2010 Expected Deaths: 4

5 Statistics from : 5 American Cancer Society estimated >42,000 cases in 2009

6 6

7 5 Year Survival from : 7 In 2008, >35,000 deaths (compare to 40,930 deaths in 2008 from breast cancer)

8  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 8

9 Anatomy & Function of the Pancreas: Spongy, 6-inch-long organ located behind the stomach. Produces digestive enzymes. Produces hormones that regulate the body’s use of starches and sugars. 9

10 10

11 11

12  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 12

13  More than 95% of all pancreatic cancer begins in the exocrine pancreas.  Less than 5% begins in the endocrine pancreas. Main Types: 13

14  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 14

15 15

16 16

17 Pancreatic Cancer: Carcinogenesis 17

18  The genetic basis is extremely complex and heterogeneous  An average of 63 genetic abnormalities per tumor  = individualized treatment. Unique Characteristics: 18

19  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 19

20  You are at an increased risk if you:  Are over 60  Are overweight or obese  Have diabetes  Smoke  Have a family history of Pancreatic Cancer  Are African American  Have chronic inflammation of the pancreas  blood type A, B, or AB Risk Factors: &view=article&id=2148:nicotine-raises-blood-sugar-levels-in- lab&catid=1:latest-news&Itemid=50 20

21  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 21

22  Abdominal Pain  Stomach Pain  Diarrhea  Fatigue  Fainting  Weight gain Signs & Symptoms for Endocrine: autism/story?id=

23  Vague sporadic discomfort  Upper abdominal or lumbar pain which worsens at night  Back pain aggravated by lying flat, relieved when sitting up  Radiating pain to the back  Pain occurring several hours after eating  Loss of appetite  Weight loss  Jaundice  Depression Signs & Symptoms for Exocrine: remedies/jaundice.php 23

24  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 24

25  Transabdominal ultrasound  Endoscopy  Ultrasound  Angiogram  Biopsy  CT scans  Endoscopic Retrograde Cholangiopancreatogram (ERCP)  Elevated blood levels of bilirubin Tests for Diagnosis: 25

26  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 26

27  Gastrinoma  Insulinoma  Miscellaneous  Recurrent Staging for Endocrine: NSF 27

28  Stage 1A: Tumor found only in pancreas, ≤ 2cm  Stage 1B : Tumor found only in pancreas, > 2cm  Stage 2A : Cancer spread to nearby organs but does not involve celiac axis or superior mesenteric artery  Stage 2B : Cancer spread to regional lymph nodes  Stage 3 : Cancer spread to celiac axis or the superior mesenteric artery  Stage 4 : Distant metastasis Staging for Exocrine:

29  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 29

30  Still considered largely incurable.  Low survival rates are most likely due to:  < 10% of patients' tumors are confined to the pancreas at time of diagnosis  Progressed malignancy The Prognosis: ws/local/Early-Detection-Can-Mean- Survival-For-Some-With-Pancreatic- Cancer html 30

31  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 31

32  Increase in cruciferous vegetables (cabbage), Folic acid, and Vitamin C.  (A) Alpha-lipoic acid  (PA) Curcumin  (PS) Genstein  (A) Green tea  (A) limonene  (P) Melatonin  (A) Mistletoe  (PSA) Omega-3 fatty acid  (S) Probiotics  (P) Selenium  [P= preventative, A= anticancer, S= supportive] Diets that are Thought to Help: 32

33  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 33

34  When tumors can be removed  Can remove all, or part of the pancreas  Whipple procedure.  Long term survival: 15-20% with a median survival rate of around months.  Recurrence is about 85% Surgery: surgery.html 34

35  Uses radiation in order to damage the cancer cells and prevent them from growing.  This is given 5 days a week, for 5-6 weeks.  Side effects: nausea, vomiting, and diarrhea. Radiation Therapy: 35

36  Kills cells that are growing or multiplying.  Given in cycles: Treatment, followed by recovery.  Side effects: More likely to get infections, hair loss, digestive problems including nausea and vomiting. Chemotherapy: that-chemotherapy-working.html 36

37  Designed to restore the patients immune system.  BRMs  Side effects: flu-like symptoms, nausea, vomiting, and diarrhea. Biological Therapy/ Immunotherapy: patient-heal-thyself-body 37

38  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 38

39  New targeted agents are in clinical development, including:  Small-molecule inhibitors of oncogenes and signaling pathways  Monoclonal antibodies targeting cell-membrane proteins  Nanotechnology and adenoviral agents The Future: experiments/scientific-method.htm 39

40  Statistics in the US  Function of the Pancreas  Types of Pancreatic Cancer  An Overview of Pancreatic Cancer  Who’s at Risk  Signs/Symptoms  Tests  Staging  Prognosis  Diets  Treatments  Future of Pancreatic Cancer  References Content of Pancreatic Cancer Tutorial: 40

41  htm htm htm  y.html y.html y.html     “Choices- The Most Complete Sourcebook for Cancer Information.” Morra, Potts. 4 th Edition. Harper Collins Publishers Inc. New York, NY. Oct  “The Definitive Guide to Cancer- An Integrative Approach to Prevention, Treatment, and Healing.” Alschuler, Fabno, Gazella. 3 rd Edition. Random House, Inc. New York InnoVision Health Media.  _Pancreatic_Cancer.htm _Pancreatic_Cancer.htm _Pancreatic_Cancer.htm   References: 41


Download ppt "{ Understanding the “Silent” Disease: Pancreatic Cancer Tara Woodard 1."

Similar presentations


Ads by Google