Presentation on theme: "DISCOVERY OF THE STRUCTURE OF DNA Hank Oliver and Chelsea Peacock."— Presentation transcript:
DISCOVERY OF THE STRUCTURE OF DNA Hank Oliver and Chelsea Peacock
Frederick Griffith Discovered the process called transformation Found a transforming agent that survived heat and change a bacteria to virulent
Oswald Avery and Colleagues Proved DNA was the transforming compound Used protein-destroying enzymes to destroy proteins, RNA-destroying enzymes to destroy RNA, and DNA- destroying enzymes to destroy DNA. Transformation was stopped when DNA-destroying enzymes were used.
Alfred Hershey & Martha Chase Performed experiment with T2 bacteriophage Using radiolabeled proteins and DNA and followed them. Experiment proved DNA was transforming agent
Rosalind Franklin & Raymond Gosling Worked together to produce the first X-ray diffraction pictures of DNA Their picture of DNA was stolen by Watson & Crick to determine the structure of DNA
Erwin Chargaff The amount of cytosine equals the amount of guanine and the amount of adenine equals the amount of thymine. Adenine ALWAYS pairs with Thymine; Guanine ALWAYS pairs with Cytosine – Chargaff’s Rule
Maurice Wilkins Studied the orientation of purines and pyrimidines in DNA Developed well-defined X-ray diffraction pictures of DNA which led to Watson and Crick’s DNA model
James Watson & Francis Crick First to determine structure of DNA Double helix Chargaff’s Rule Made of sugar-phosphate backbone with bases hydrogen bonded together holding two strands together
References Maurice Wilkins Picture http://scarc.library.oregonstate.edu/coll/pauling/dna/pictures/portrait-wilkinsmodel.html Watson and Crick Picture http://www.chemheritage.org/discover/online-resources/chemistry-in-history/themes/biomolecules/dna/watson-crick- wilkins-franklin.aspx DNA Structure http://library.thinkquest.org/24355/data/details/media/dnastructure.html
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