Presentation on theme: "What is new in Malaria Management ? Dr. PC Bhattacharyya Sr. Consultant Physician down town hospital Guwahati,Assam."— Presentation transcript:
What is new in Malaria Management ? Dr. PC Bhattacharyya Sr. Consultant Physician down town hospital Guwahati,Assam
Current Scenario No significant development in management since the advent of artemisinin. Many new drugs are in experimental stage Various combination of different drugs are tried with variable success Newer investigations contributed much towards the successful management
Newer Investigations 1.Serological Tests : 2.Molecular biological techniques DNA Probes RNA probes 3.Transcript amplification system and target amplification by PCR 4.Probe amplification ring Q beta replicase 5.Compound or ‘Christmas tree’ Probes 6.Fluorescence microscopy
Serological tests Test Current applicationSource of antigens (or antibodies) Antibodies Identified ImmunoprecipitationEpidemiological studies & research Erythrocytic scizonts & soluble antigens IgG IgM ImmunofluroscenceEpidemiological studies research & aid to diagnosis Erythrocytic scizonts IgG IgM IgA Indirect haemagglutination Epidemiological surveysAntigen coated erythrocytes IgG ELISA Epidemiological studies and aid to diagnosis Soluble antigen or antibodies igG (IgM) RIA ResearchSoluble antigensIgG IgM Merozoite inhibition in culture ResearchMerozoite from erythrocytic schizonts IgG IgM
Management (i) 1.Immediate general management 2.Immediate admission in ICU 3.Resuscitation 4.Airway/Circulation by ALS technique 5.ABG/Serum electrolyte estimation 6.Coagulation profile 7.Detection of pulmonary oedema and ARDS & ventilatory support
Your consent to our cookies if you continue to use this website.