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LASER Doppler analysis of blood flow in ischemic diabetic mouse hindlimbs injected with PBMCs or vehicle on theday of femoral artery ligation Ola Awad,

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Presentation on theme: "LASER Doppler analysis of blood flow in ischemic diabetic mouse hindlimbs injected with PBMCs or vehicle on theday of femoral artery ligation Ola Awad,"— Presentation transcript:

1 LASER Doppler analysis of blood flow in ischemic diabetic mouse hindlimbs injected with PBMCs or vehicle on theday of femoral artery ligation Ola Awad, et al. ATVB 2006;26:758-764

2 Inflammatory Assessment of Ischemic Muscle Ola Awad, et al. ATVB 2006;26:758-764

3 Mouse muscle histology Ola Awad, et al. ATVB 2006;26:758-764

4 CD34 + PBMC- treated ischemic muscle Ola Awad, et al. ATVB 2006;26:758-764

5 Vascular parameters in hamstring muscles Bars indicate SEM. N=3 to 4 per group. *P<0.05 relative to all other groups Ola Awad, et al. ATVB 2006;26:758-764

6 Relative protein levels of angiogenic factors and their receptors in ischemic limbs - Changes in VEGF and the angiopoietin system 1 day after surgery and cell treatment Bars indicate SEM. P<0.01 solid bracket. P<0.05 dashed bracket. N=4 to 6 mice per group Ola Awad, et al. ATVB 2006;26:758-764

7 Relative protein levels of angiogenic factors and their receptors in ischemic limbs - Changes in VEGF and the angiopoietin system 5 days after surgery and cell treatment Bars indicate SEM. P<0.01 solid bracket. P<0.05 dashed bracket. N=4 to 6 mice per group

8 Ola Awad, et al. ATVB 2006;26:758-764 Relative protein levels of angiogenic factors and their receptors in ischemic limbs - Changes in MCP-1 protein 1 day and 5 days after surgery and cell treatment Bars indicate SEM. P<0.01 solid bracket. P<0.05 dashed bracket. N=4 to 6 mice per group


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