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8.1, 8.2, 8.3 Chapter 8 DNA.

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Presentation on theme: "8.1, 8.2, 8.3 Chapter 8 DNA."— Presentation transcript:

1 8.1, 8.2, 8.3 Chapter DNA

2 DNA Deoxyribonucleic Acid How Did we Discover DNA?

3 Transformation 1928 Griffith with mice
One disease bacteria transformed the other harmless bacteria into a disease bacteria

4 R S

5 Is the genetic material made of DNA or protein
Hershey-Chase Experiment- (1952) Studied viruses known as bacteriophages Is the genetic material made of DNA or protein

6 DNA made of monomers of nucleotides
Nucleotides consist of 3 parts 5-carbon sugar deoxyribose Phosphate group Nitrogen base

7 Chargaff’s Rule A=T C=G Adenine bonds with Thymine
Cytosine bonds with Guanine Nitrogen bases are held together by hydrogen bonds A=T C=G


9 X-Ray evidence- 1950’s Rosalind Franklin used X-ray diffraction to study structure of DNA. Concluded structure was coiled like a spring (double helix)

10 DNA is a double helix two complementary strands
Strands consist of : Sugar phosphate backbone Nitrogen base rungs

11 DNA unzips- hydrogen bonds are broken
Each parent strand serves as a template to form new complementary strand DNA polymerase- adds new nucleotide by base pairing rule. DNA polymerase proofreads each new DNA strand and repairs errors, unchecked error = mutation In prokaryotic cells replication is in 1 region In Eukaryotic cells it is in many regions

12 When DNA has completed replication there are two double strands
Each strand contains one side of the parent strand plus a new complementary strand

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