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Chapter 8 DNA 8.1, 8.2, 8.3. DNA Deoxyribonucleic Acid.

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Presentation on theme: "Chapter 8 DNA 8.1, 8.2, 8.3. DNA Deoxyribonucleic Acid."— Presentation transcript:

1 Chapter 8 DNA 8.1, 8.2, 8.3

2 DNA Deoxyribonucleic Acid

3 1928 Griffith with mice One disease bacteria transformed the other harmless bacteria into a disease bacteria

4 S R

5 Hershey-Chase Experiment- (1952) Studied viruses known as bacteriophages Is the genetic material made of DNA or protein

6 DNA made of monomers of nucleotides Nucleotides consist of 3 parts 5-carbon sugar deoxyribose Phosphate group Nitrogen base

7 Chargaff’s Rule Adenine bonds with Thymine Cytosine bonds with Guanine Nitrogen bases are held together by hydrogen bonds A=T C=G

8

9 X-Ray evidence- 1950’s Rosalind Franklin used X-ray diffraction to study structure of DNA. Concluded structure was coiled like a spring (double helix)

10 double helix DNA is a double helix two complementary strands Strands consist of : Sugar phosphate backbone Nitrogen base rungs

11 1.DNA unzips- hydrogen bonds are broken 2.Each parent strand serves as a template to form new complementary strand 3.DNA polymerase- adds new nucleotide by base pairing rule. 4.DNA polymerase proofreads each new DNA strand and repairs errors, unchecked error = mutation In prokaryotic cells replication is in 1 region In Eukaryotic cells it is in many regions

12 When DNA has completed replication there are two double strands Each strand contains one side of the parent strand plus a new complementary strand


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