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TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes by Roshan L. Shrestha, Naoka Tamura, Anna Fries, Nicolas Levin, Joanna Clark, and Viji M. Draviam Open Biology Volume 4(6): June 4, 2014 ©2014 by The Royal Society
TAO1-depleted cells display chromosome congression defects. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
Rescue of TAO1 depletion-induced chromosome congression defects. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
TAO1 is required to maintain dynamic microtubules during mitosis. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
TAO1-depleted cells display mis-segregating lagging chromosomes. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
Taxol or MPS1 inhibitor treatments in TAO1-depleted cells. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
Correcting erroneous kinetochore–microtubule attachments requires TAO1. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
Model of TAO1 depletion-induced mis-segregation arising from defective microtubule stability. Roshan L. Shrestha et al. Open Biol. 2014;4: ©2014 by The Royal Society
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Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 4.8 Mitosis maintains the chromosome number of the parent.
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