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Hyperplasia in Koi Cindy Badder, KHA Mt. Washington, KY Louisville Koi Club.

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Presentation on theme: "Hyperplasia in Koi Cindy Badder, KHA Mt. Washington, KY Louisville Koi Club."— Presentation transcript:

1 Hyperplasia in Koi Cindy Badder, KHA Mt. Washington, KY Louisville Koi Club

2 What is Hyperplasia? Hyperplasia is a fancy way of saying abnormal increase in cell numbers or cell numbers "gone wild" leading to a size increase of the affected tissue or organ; it can also be used as another term for benign growth, or tumor. Hyperplasia is a fancy way of saying abnormal increase in cell numbers or cell numbers "gone wild" leading to a size increase of the affected tissue or organ; it can also be used as another term for benign growth, or tumor.

3 Case History Person requested help on koi forum for fish that had abnormal growths Person requested help on koi forum for fish that had abnormal growths Pond is 400 gallons Pond is 400 gallons Problem started 3 years ago with fish #1 Problem started 3 years ago with fish #1 Tumor grew, then fell off Tumor grew, then fell off

4 Fish #1

5 Additional Details Other Koi and goldfish started to develop growths Other Koi and goldfish started to develop growths Small amount of algae on rocks Small amount of algae on rocks Water analysis: Water analysis: pH is normal, pH is normal, KH 120, KH 120, Nitrite 0, Nitrite 0, Nitrate 20 Nitrate 20

6 Fish # 2

7 Observations Fish eat and act normal Fish eat and act normal Pond owner originally thought it was parasite related Pond owner originally thought it was parasite related Bumps are hard Bumps are hard

8 Fish #3

9 My Suggestions Pond is over crowded, more water changes Pond is over crowded, more water changes Possibility of Acriflavine for Lymphocystis Possibility of Acriflavine for Lymphocystis Lymphocystis is a viral disorder Lymphocystis is a viral disorder Acriflavine (surface bactericide) Acriflavine (surface bactericide) This treatment wouldn’t work on cancers or hyperplasia This treatment wouldn’t work on cancers or hyperplasia

10 Lymphocystis Cells on a Slide ( Picture from Koivet )

11 Hyperplasia can be confused for lymphocystis (increase in cell size), and various bacterial or fungal infections. Hyperplasia can be confused for lymphocystis (increase in cell size), and various bacterial or fungal infections. Lymphocystis usually appears whitish in color, and distinct clusters of enlarged cells can be easily seen which have a visibly enlarged blood supply system supporting the rapidly expanding lymphocystis cells Lymphocystis usually appears whitish in color, and distinct clusters of enlarged cells can be easily seen which have a visibly enlarged blood supply system supporting the rapidly expanding lymphocystis cells Hyperplasia or Lymphocystis?

12 Lymphocystis

13 Many irritants can cause hyperplasia Many irritants can cause hyperplasia Chemical irritants Chemical irritants Toxic pollutants Toxic pollutants Pond decoration or structures Pond decoration or structures Aerosol sprays Aerosol sprays Open wound from injury, abrasions etc. Open wound from injury, abrasions etc. Suspended particles in the water Suspended particles in the water Causes of Hyperplasia

14 Cure and prevention Hyperplasia, will not be "cured" by antibiotics or other treatments. In fact, the application of such medications may have caused the hyperplasia to begin with, or even stimulated more such growth. Hyperplasia, will not be "cured" by antibiotics or other treatments. In fact, the application of such medications may have caused the hyperplasia to begin with, or even stimulated more such growth.

15 Transmission to Humans? Researcher handled experimentally infected fish Researcher handled experimentally infected fish Developed multiple warts on hands Developed multiple warts on hands No viral cell comparison done No viral cell comparison done Warts disappeared after working mixing concrete. Cause - basic pH? Warts disappeared after working mixing concrete. Cause - basic pH?

16 Case Update Koi have worsened Koi have worsened PO has not tried Acriflavine PO has not tried Acriflavine Fish still act normal, have appetites Fish still act normal, have appetites If I have further contact, I’ll recommend removing any sharp objects in addition to water changes If I have further contact, I’ll recommend removing any sharp objects in addition to water changes

17 Hyperplasia Increasing

18 Lessons Learned Don't assume lesions are Lymphocystis Don't assume lesions are Lymphocystis Cause may be viral or environmental Cause may be viral or environmental Not all skin growths are treatable Not all skin growths are treatable Wear gloves to protect yourself Wear gloves to protect yourself

19 Credits Dr. Adrian Lawler, P.O. Box 48, Ocean Springs. MS U.S.A.

20 Discussion


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