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Medical mycoses cutaneus subcutaneus systemic opportunistic.

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Presentation on theme: "Medical mycoses cutaneus subcutaneus systemic opportunistic."— Presentation transcript:

1 Medical mycoses cutaneus subcutaneus systemic opportunistic

2 Intact skin and mucosal surfaces serve as barriers to infection by mycotic agents. Fatty acid,pH,epithelial turnover of the skin Transferrin  to restrict the growth of several fungi. Superficial fungi dont elicit a cellular response from the host

3 Etiology Mallassezia furfur Pityriasis Versicolor Lipophillic organism Lesion: hypopigmented area contain budding yeast cells and hyphae Asymptomatic Diagnosis: KOH preparations(skin scrapping)

4 Dermatophytes Dermatophytoses(Tinea,ringworm) Infect keratinized structures Skin,hair and nail Invasive properties May evoke inflamatory reaction Three genera: - Epidermophyton - Trichophyton - Microsporum

5 Anthropophillic Zoophillic Geophillic Tinea  chronic infection (warm and humid areas of the body) Typical lesion : inflame circular border containing papules & vesicles surrounding a clear area.

6 Broken hairs and thickened broken nails Trichophyton tinea capitis in children Endothrix infections “favus”  tinea capitis in which crusts on the scalp.

7 Dermatophytid (“id”) reactions - vesicles on the fingers - response to circulating fungal antigens - the lesion do not contain hyphae Skin test with fungal extracts,eg, trichophytin

8 The normal skin is generally resistant to invasion by dermatophytes In conditions of excessive moisture,can invade keratinized structures.

9 Laboratory diagnosis 1.Microscopic  KOH preparation scrappings of skin or nail  show hyphae 2. Cultures on Sabouraud’s agar  typical hyphae and conidia 3. DNA probes 4. Test for the presence of fungal antigens or antibodies to fungal antigens.

10 Tinea Tinea capitis Tinea barbae Tinea axillaris Tinea corporis Tinea cruris  jock itch Tinea pedis  athlete’s foot

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