Presentation on theme: "Infertility He-Feng Huang Women’s Hospital, School of Medicine, Zhejiang University."— Presentation transcript:
Infertility He-Feng Huang Women’s Hospital, School of Medicine, Zhejiang University
Endocrine disease Infertility ： The inability to achieve pregnancy after regular unprotected intercourse for a period of 1 year. Dysfunctional uterine bleeding ： Abnormal uterine bleeding caused by hormonal mechanism, with no organic disease of reproductive tract and internal medical disease. Amenorrhea ： Absence or cessation of menstruation lasted more than 3 cycles or 6 months.
Normal menstruation mechanism ▷ Regulation and feedback of hypothalamus-anterior pituitary- ovary ▷ Normal ovarian function ▷ Complete uterine, normal reaction of endometrium to estrogen and progesterone ▷ Unobstructed reproductive tract
Infertility Definition: The inability to achieve pregnancy after regular unprotected intercourse for a period of 1 year. Primary infertility: never conceived within 1 year Secondary infertility: after a previous pregnancy, unable to conceive again within a 1 year period.
Etiology Female factors Male factors Female and male factors
Ovarian factors PCOS LUFS POF Ovary insensitivity syndrome Congenital abnormality Surgery or X-ray Ovarian endometriosis Ovarian tumor
PCOS Diagnosis （ 1 ） irregular menses or anovulation （ 2 ） experimental or clinical hyperandrogenism （ 3 ） polycystic ovarian morphology observed by ultrasound Accord with 2 points of the three. Symptom Menses disturbance and infertility hirsutism, acne, obesity ( BMI ≥ 25 ) Follow-up for whole life
Investigation and Diagnosis Male investigation History: general health, medications, lifestyle and reproductive health General examination Specific examination ： abnormality of genitals seminal analysis
Ethic of ART (Chinese government) The government does not support nor approve the practice of human clones; Forbid performing ART for single woman; Forbid Manufacturing Oocytes; Forbid commercial trial of zygotes and embryos; Forbid multiple pregnancy dominated ART; Forbid gender selected ART without medical indication; Forbid surrogate motherhood
Ethic of ART Challenge the course of natural reproduction Danger of inbreeding Commercial trial of zygotes and embryos Uncertainty of parenthood Risk of oocyte donation Controversy between clone and traditional family formation Clone criminality Challenge of the definition of “human” ART related regulations and laws