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IN-PERSON & AMONG PERSONS ? ? Emotionally balanced 40-45% Insensitive or less sensitive 40% ADH personality DANGER MODEL OF ASSOCIATION TRUSTING MODEL.

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Presentation on theme: "IN-PERSON & AMONG PERSONS ? ? Emotionally balanced 40-45% Insensitive or less sensitive 40% ADH personality DANGER MODEL OF ASSOCIATION TRUSTING MODEL."— Presentation transcript:

1 IN-PERSON & AMONG PERSONS ? ? Emotionally balanced 40-45% Insensitive or less sensitive 40% ADH personality DANGER MODEL OF ASSOCIATION TRUSTING MODEL OF ASSOCIATION DISTANT MODEL OF ASSOCIATION Highly Sensitive 15-20% Autistic Spectrum Collected from multiple sources & integrated by SOVEREIGN RESEARCH, LLC 2011 Insecure Attachment: Anxious & Inconsistent Secure Childhood Attachment: Collected & Consistent Secure Childhood Attachment: Collected & Consistent Insecure Attachment: Distant & Evasive Insecure Attachment: Distant & Evasive PERSONALITY SPECTRUM TM

2 INCREASED VULNERABILITY TO ENVIRONMENTAL TOXINS TOXIN ACQUISITION BY INGESTION OR INHALATION INFLAMMATION IN MUCUS MEMBRANES & REDUCED DEFENSIVE & FILTERING CAPACITY RECRUITMENT OF IMMUNE MEDIATORS INDUCE STRESS RESPONSE CRH - corticotropin releasing hormone TOXIC BYPRODUCTS, IMMUNE & INFLAMMATORY MEDIATORS MAY BLOCK CORTISOL PRODUCTION eg. DEFENSINS INCREASE INFLAMMATION & FURTHER WEAKEN MUCOUS MEMBRANES COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

3 WHY DOES AUTISTIC PERSONALITY EMERGE AT A VARIABLE AGE? Increased innate reactivity to stress (genetic predisposition) MAGNITUDE OF STRESS (OVERWHELMING VS. STIMULATIVE) REPETITIVE EXPOSURE TO STRESS (MISHANDLING, TOXINS, PARENTAL FEUDING...) STAGE OF LIFE 1st 2 YRS..TODDLER..SCHOOL YRS..PUBERTY..COLLEGE..ADULTHOOD COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

4 BEHAVIORAL CURVE-BALL TRADITION COURTESY SMITH, BD (1983); EXTRAVERSION & ELECTRODERMAL ACTIVITY; AROUSABILITY & THE INVERTED U; Personality & Individual Differences, Vol 4; p 411-420 SENSITIVES & INSENSITIVES VARY WIDELY IN BASAL AROUSABILITY SENSITIVES ARE MORE EMOTIONALLY AROUSABLE BY MODERATE STRAIN INSENSITIVES: CHOKE UNDER PRESSURE SENSITIVES: THRIVE UNDER PRESSURE COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

5 Stimulation (eustress) DISTRESSDISTRESS Increasing perceived stress Decreasing perceived stress MAGNITUDE OF STRESS RESPONSE ABSENCE OF STIMULATION [IDLENESS] IS MORE STRESSFUL THAN ANY TANGIBLE CHALLENGE SENSORY OVERLOAD: THE AFTERMATH COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

6 IMPACT OF NEUTRAL, PLEASANT & UNPLEASANT EXPERIENCES ON STRESS RESPONSE FROM STRESS WITHOUT DISTRESS, BY HANS SELYE COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

7 TRANSIENT SENSORY OVERLOAD VS. PROLONGED BURNOUT HANS SELYE'S GENERAL ADAPTATION SYNDROME “THE STRESS OF LIFE”

8 CENTRAL REALIZATION OF THREAT OR STRAIN LHPA AXIS (HYPOTHALAMUS /PITUITARY) CRH & ACTH LHPA AXIS (ADRENALS) CORTISOL ALARM, MOTIVATION & RECRUITMENT MESSAGE DISTRIBUTED PERIPHERAL SYMPATHETIC GANGLIA & ADERNALS EPINEPHRINE CENTRAL SYMPATHETIC (LOCUS CERULEUS) NOREPINEPHRINE HYPO- CRETINS ? HYPO- CRETINS ? COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

9 HIGH MOOD LOW MOOD NEGATIVE MOOD POSITIVE MOOD SENSITIVE INSENSITIVE Neg hi mood: irritable, creative Neg lo mood: thought synthesis Pos hi mood: Enron exec. Pos lo mood: follower COPYRIGHT SOVEREIGN RESEARCH, LLC 2011

10 ChangeEffect 1- Increase hypothalamic CRH production Increase stress reactivity and anxiety 2- Increase amygdala CRH production Increase stress reactivity and fear learning 3- Decrease cortisol receptors in hippocampus and hypothalamus Increase difficulty terminating stress response 4- Decrease GABAA receptors in hippocampus Increase difficulty terminating the stress response 5- Increase brain noradrenalin activity Increase reactivity to stress and irritability 6- Increase serotonin availability and utilization Difficulty gaining dominance over personal life All these effects cumulatively result in limiting the baby’s potential later in life. These effects often result in a life marred by desperation, perpetual failure and loss of self- esteem.

11 Target tissue or systemBiologic effectFunctional/clinical correlate LiverIncreased glucose synthesisIncrease blood sugar levels LiverDecrease HDL productionIncrease cholesterol in blood Muscle and fat Glycogen and protein breakdown to form glucose Increase blood sugar levels Muscle and fat Fat breakdown and mobilization to blood Enhanced reliance on fatty acids for fuel – facilitator of obesity and aging Muscle and fatDecrease sensitivity to insulin actions Facilitate insulin resistance – a precursor to diabetes Heart and blood vessels Increase heart rate and blood vessel tone Increase blood pressure, blood vessel wall thickening and risk of blood clots Growth axis Decrease GH release*, tissue sensitivity to GH, IGF1 and IGF2 Delay in growth and development in children; bony frame; reduced tissue regeneration Reproductive system Inhibition of reproductive hormones including LH, progesterone and testosterone; render target tissues resistant Sexual maturity problems at puberty, cycle irregularities, premenstrual cramping, reduced fertility, hot flashes, low libido Thyroid axis Decrease triiodothyronine, the active thyroid hormone; Inhibition of TSH, short-term only Delay in growth and development in children; decrease metabolic rate SkeletonReduced new bone formation Osteopenia and osteoporosis – both genders equally Gastrointestinal Inhibit stomach acid; reduce movement of food along; Bloating, food fermentation, loose stools, constipation, irritable bowel, pain, Gastrointestinal weaken gut immune defenses; increase permeability (leaky gut); weaken friendly bacteria in colon free access of ingested toxins and food additives to rest of body; succumbing to microbes including yeast and parasites. Childhood stressFurther sensitizes stress pathwaysIncrease likelihood of anxiety and depression for the rest of life

12 SOY All soy containing foods (including soy milk) facilitate the disposition of thyroid hormone from the body CRUCIFEROUS VEGETABLES Broccoli, Cauliflower, Brussels, kholrabi… All crucifers contain a chemical (isothiocyanate) which is a toxin for the thyroid gland GLUTEN CONTAINING GRAINS RYE, BARLEY, WHEAT… Gluten sensitive individuals of all ages show a deterioration in thyroid function while consuming grains; and an improvement on gluten-free diet CORTAID CREAM & OTHER OVER THE COUNTER STEROID CREAMS Cortisol (hydrocortisone), a naturally occurring steroid, in excess amounts may lower active thyroid hormone in the body ASTHMA INHALERS & OTHER PHARMACEUTICAL STEROIDS Synthetic variants of cortisol show a more accentuated effect compared to cortisol LEMON BALM (Melissa Officinalis) an herb commonly used to help with sleep may reduce thyroid function Melatonin supplements Melatonin and other sleep aids also may lower levels of active thyroid hormone Low carbohydrate dietsMay lower levels of active thyroid hormone in body

13 MALES BETTERFEMALES BETTER Spatial abilities including mental rotations, route learning, and visualization of spatial relationships Verbal skills including fluency, rate of speech acquisition, spelling, and grammar Mathematical reasoning and problem solving Computational accuracy and procedural knowledge of arithmetic and mathematics Gross motor skills that involve strength Fine motor skills and finger dexterity Short term memory including memory for object locations


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