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Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins Marco Pirazzini,

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Presentation on theme: "Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins Marco Pirazzini,"— Presentation transcript:

1 Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins Marco Pirazzini, Domenico Azarnia Tehran, Giulia Zanetti, Aram Megighian, Michele Scorzeto, Silvia Fillo, Clifford C. Shone, Thomas Binz, Ornella Rossetto, Florigio Lista, Cesare Montecucco Cell Reports Volume 8, Issue 6, Pages (September 2014) DOI: /j.celrep Copyright © 2014 The Authors Terms and Conditions Terms and Conditions

2 Figure 1 Cell Reports , DOI: ( /j.celrep ) Copyright © 2014 The Authors Terms and Conditions Terms and Conditions

3 Figure 2 Cell Reports , DOI: ( /j.celrep ) Copyright © 2014 The Authors Terms and Conditions Terms and Conditions

4 Figure 3 Cell Reports , DOI: ( /j.celrep ) Copyright © 2014 The Authors Terms and Conditions Terms and Conditions

5 Figure 4 Cell Reports , DOI: ( /j.celrep ) Copyright © 2014 The Authors Terms and Conditions Terms and Conditions

6 Cell Reports , DOI: ( /j.celrep ) Copyright © 2014 The Authors Terms and Conditions Terms and Conditions


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