Presentation on theme: "Fate of Cells The developing embryo undergoes morphogenesis in order to create different tissues and organs through cleavage, gastrulation, and organogenesis."— Presentation transcript:
1 Fate of CellsThe developing embryo undergoes morphogenesis in order to create different tissues and organs through cleavage, gastrulation, and organogenesisMorphogenesis… changing of form, shape, or functionCleavage… pinching off to form 2 structures or a division within a structureGastrulation… forming a cavityOrganogenesis… specialization of tissue for a function
2 Cell DifferentiationCells are totipotent in the first 16 cells of the of the blastocystPotency is reduced with each cell specialization there afterInitial differentiation due largely to uneven distribution of cytoplasmic determinants in the yolk of the eggEgg is polarized creating heterogeneous cytoplasmCleavage creates uneven distribution of mRNA and asymmetrical cell divisionProcess of induction causes the specialization of most cellsCreated through contact via diffusible chemical signals
3 Fate MappingManipulation of embryonic cells to determine the lineage of cells from the first cleavage event
4 Cellular Asymmetries Axes of body plan Anterior-posterior, ventral-dorsal, right-leftEstablishes bilateral symmetry1st step in morphogenesis and tissue/organ formationBicoid region of fliesDetermined by melanin in the yolk during oogenesisGravity helps determine anterior/posterior axis in chickspH determines ventral/dorsal…marked by the gray crescent in many embryos
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