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Bibliography of hypertrophy - Scalrovsky. 1 Fijensen en la izquierda muestra las presiones desarrolladas en ela ratas con hipertrofia, la hipertrofia.

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Presentation on theme: "Bibliography of hypertrophy - Scalrovsky. 1 Fijensen en la izquierda muestra las presiones desarrolladas en ela ratas con hipertrofia, la hipertrofia."— Presentation transcript:

1 Bibliography of hypertrophy - Scalrovsky

2 1

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4 Fijensen en la izquierda muestra las presiones desarrolladas en ela ratas con hipertrofia, la hipertrofia disminuye la tension intramural,mientras Que no dessarrollan hipertension hay una alta tension intramural

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6 Ley de Laplace

7 Kel Kelly SHJ et al clonocall exp phasrmacilogy physiology 33.642;2006 Prepado de Langerdof en un raton, registra los potenciales de epicardio y endocardio y un globo intracavitaio r Note que que el potencial de accion del endocardio se acorta cion el aumento de la pre4sion intracavitaria,pero no hay cambios en el potencial de accion del epicardio end epi

8 Molecular biology could explain the pattern of high voltage and fast conduction of R waves in left ventricle hypertrophy The high R wave in v4-5 in apical remodeling indicates the addition of sarcomeres in the longitudinal axis

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10 2004

11 Conclusions androgen receptors In cardiac myocytes from multiple species, including normal men and women,in a context that permits the cardiac phenotype and produce hypertrophy by direct receptors- specific mechanism for therapeutical or ilicit use of androgen in men

12 REModelacion tioca de un hipertenso Con remodelacion fibrotica sin hypertrofia muscular de alto riego para arritmias atriales y ventricularesל a)Una tipica remodelacionhypertrofia ventricular musculat

13 Spinale F, Physiol Rev 2007 Spinal;e G Physiological Review 2007

14 Metalloproteinases(MMP) regulate collagen I concentration in extra cellular matrix. The collagen turnover is about 90 days. Tissue Inhibitor Metalloproteinase (TIMP) regulates the concentration of MMP Lombardi R et al, Circulation 2003

15 Physiol. Rev. 87: 1285-1342, 2007; doi:10.1152/physrev.00012.2007 0031-9333/07 $18.00 Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function Francis G. Spinale Division of Cardiothoracic Surgery, Medical This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (25) Citing Articles via Google Scholar Google Scholar Articles by Spinale, F. G. Search for Related Content PubMed PubMed Citation Articles by Spinale, F. G. Physiol. Rev. 87: 1285-1342, 2007; doi:10.1152/physrev.00012.2007 0031-9333/07 $18.00 Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function Francis G. Spinale Division of Cardiothoracic Surgery, Medical This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (25) Citing Articles via Google Scholar Google Scholar Articles by Spinale, F. G. Search for Related Content PubMed PubMed Citation Articles by Spinale, F. G. Physiol. Rev. 87: 1285-1342, 2007; doi:10.1152/physrev.00012.2007 0031-9333/07 $18.00 Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function Francis G. Spinale Physiol. Rev. 87: 1285-1342, 2007; doi:10.1152/physrev.00012.2007 0031-9333/07 $18.00

16 . Part I: signal transduction and basic electrophysiological mechanisms Andreas GoetteAndreas Goette eurpace1,* and1* Uwe Lendeckel2 ++ Author Affiliations 1Division of Cardiology, University Hospital Magdeburg, Leipzigerstr. 44, Magdeburg 39120, Germany 2Institute of Experimental Internal Medicine, University Hospital Magdeburg, Magdeburg 39120, Germany *Corresponding author. Tel: +49 391 6713225; fax: +49 391 671 3202.E-mail address: andreas.goette@medizin.uni-magdeburg.deandreas.goette@medizin.uni-magdeburg.de Received October 17, 2007. Accepted November 28, 2007. Next Section Abstract In the recent years, a tremendous amount has been learned about the pathophysiology and molecular biology of the cardiac angiotensin II system. Interestingly, the angiotensin II appears to have several effects on cardiac electrophysiology, which have not been fully appreciated so far. Therefore, this review will highlight on the basic knowledge of signal transduction and electrophysiological effects of angiotensin II, which may have an impact on the occurrence of cardiac arrhythmia. Key words Angiotensin Arrhythmias Fibrillati


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