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Bio-Incubators ISBA Meeting Pune March 18, 2012 17-19, March 2012ISBA_RD_BIRAC 20121 Ravi Dhar, Ph.D. BIRAC (previously DBT_BIRAP)

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Presentation on theme: "Bio-Incubators ISBA Meeting Pune March 18, 2012 17-19, March 2012ISBA_RD_BIRAC 20121 Ravi Dhar, Ph.D. BIRAC (previously DBT_BIRAP)"— Presentation transcript:

1 Bio-Incubators ISBA Meeting Pune March 18, , March 2012ISBA_RD_BIRAC Ravi Dhar, Ph.D. BIRAC (previously DBT_BIRAP)

2 Acknowledgements ISBA, Dr. R. Jagdale Secretary, Prof. M. K. Bhan, DBT Dr. Renu Swarup, DBT & BIRAP Mr. Rajneesh Kumar, BIRAP Colleagues at DBT, BIRAP, IITs Various Expert Committee Members Various stakeholders 17-19, March 2012ISBA_RD_BIRAC 20122

3 Definition as Perceived “A Bioincubator is a building designed for housing R&D driven companies active in Life sciences. It is mostly closely related to a neighbouring university. A Bioincubator is a Business incubator targeted towards Life Sciences helping start-up companies. Entrepreneurs with feasible projects in Life Sciences are selected and admitted into the incubators, where they are offered a specialized menu of support resources and services, including mentoring”Life sciencesuniversity Business incubatorstart-up companies 17-19, March 2012ISBA_RD_BIRAC 20123

4 Bio-incubator Scenario in India Life science (mixed) incubators: 52 N: 10 S: 27 E: 5 W: 8 Exact Classification not clear 17-19, March 2012ISBA_RD_BIRAC 20124

5 17-19, March 2012ISBA_RD_BIRAC Evolution of DBT over years Basic Research/Discovery Innovation Enterprise

6 17-19, March 2012ISBA_RD_BIRAC Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Funding Support

7 17-19, March 2012ISBA_RD_BIRAC Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Phase-I: Basic Infrastructure/Capacity Funding Support

8 17-19, March 2012ISBA_RD_BIRAC Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Phase-I : Basic Infrastructure/Capacity Phase-II: Product Development Public or Private Incubator Space or SMEs F unding Support I II

9 17-19, March 2012ISBA_RD_BIRAC Phase I to II Syndrome ? We need to get out of this syndrome

10 Parks & Incubators DBT initiated several Parks & incubators sometime back Definitions: Science Parks: An area usually linked with a university where scientific research and commercial development are carried on in cooperation Bio-incubators: Incubators specifically are meant to allow young incubatees / start-up companies to initiate and dabble into entrepreneurship 17-19, March 2012ISBA_RD_BIRAC

11 DBT Mandate Funding of various Research & Technology schemes by DBT National Biotech Policy (1997) mandated 30% funding for PPP BIRAP (=BIRAC) funded schemes: SBIRI BIPP Bio-Incubators CRS BIG Capacity Building + Training 17-19, March 2012ISBA_RD_BIRAC BIRAP

12 BIRAC Mandate 17-19, March 2012ISBA_RD_BIRAC Trigger, Transform & Tend- Biotech Start-ups to convert innovative research in Public and Private sector Support & Strengthen SME’s, facilitates high risk research, innovation and product development Financial, Infrastructural, Institutional & Mentoring support for budding entrepreneurs Encourage Knowledge Networking among biotech entrepreneurs at National & International Level Policy and Institutional Support for all Stakeholders in Biotech Conceptualize and Support development of affordable, novel, deployable products and technologies in Healthcare, Agriculture, Environment Bio- energy involved in PPP Promote Secondary Agriculture for providing opportunity in entrepreneurship & employment.

13 BIRAC Evolution 17-19, March 2012ISBA_RD_BIRAC It is linked to Evolution of DBT over years

14 How we moved ….. National Biotechnology Development Strategy Sept., 2007 Pilot BIRAP Sept., 2008 Stakeholder Consultations, innovation support programmes, skill augmentation Approval for BIRAC Stakeholder Consultations, Future blue-print for formalization & action Section 25 Company Not-for-profit/ for public good/ Private Company Company Registered on , March 2012ISBA_RD_BIRAC

15 17-19, March 2012ISBA_RD_BIRAC

16 17-19, March 2012ISBA_RD_BIRAC Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Phase-I: Basic Infrastructure/Capacity Phase-II: Product Development Public or Private Incubator Space or SMEs Funding Support BIG Grant

17 An Ideal BIRAC Incubator Building designed for housing incubatees or start-up entrepreneurs active in Life Science Presence of neighbouring academic organizations or universities or hospitals or R&D Industrial units. It therefore is a like a Business Incubator targeted towards Life Sciences helping start-ups. Entrepreneurs with feasible projects in Life Sciences are selected and admitted into the incubators as tenants, where they are offered a specialized menu of support resources and services, including mentoring , March 2012ISBA_RD_BIRAC

18 17-19, March 2012ISBA_RD_BIRAC Wet Lab space & Equipment Office Cubicles for Incubatees Admin/IT/ Security/ services/Library Food Court/ Canteen Resting space Reagents & Chemical Store

19 Who Occupies the Bio-incubator Incubatees (fresh M.Tech/Ph.D./M.B.B.S/ etc) Parties going to be SMEs 17-19, March 2012ISBA_RD_BIRAC

20 17-19, March 2012ISBA_RD_BIRAC Benefits of Incubators Creating jobs Building or accelerating growth of local academic and industry clusters Fostering a community's entrepreneurial climate Technology commercialization Diversifying local economies Business creation and retention Encouraging women or minority entrepreneurship Identifying potential spin-in or spin-out business opportunities Community revitalization

21 Issues in India Seed Funding Long term Sustainability Business Models in mind: – Incubatees : generally bereft – SMEs: have a strategy Technology Platform Model: (Start-ups that rent/sell their technology/product to pharma/biotech companies) (?) RIPCO Model: (Start-ups that research and develop a new product to finally license it to a big pharma/biotech company in exchange for a royalty on sales) FIPCO Model: (Start-ups that launch their own Product) NRDO model: (Start-ups that buy a “discarded” promising drug from big pharma and use their technology to bring it to market) 17-19, March 2012ISBA_RD_BIRAC

22 LOI on BIRAP Bio-Incubator 17-19, March 2012ISBA_RD_BIRAC Department of Biotechnology Ministry of Science and Technology Government of India Call for Letters of Intent (LOI) For DBT-BIRAP Support for Establishing and Strengthening Bio-Incubators/Innovation Centers for Research, Innovation and Technopreneurship. Biotechnology Industry Research Assistance Programme, (BIRAP) is a programme of the Department of Biotechnology, Govt. of India, with an objective to assist and promote emerging biotech entrepreneurs and facilitate innovative research and development in existing small, medium as well as large industries. Biotech incubator acts as a catalyst that would stimulate research & develop and for creating of new biotechnology ventures/startups. In order to give thrust to the biotechnology industry in the country, DBT-BIRAP aims to provide financial support in form of soft loans and grants for Strengthening the already existing Bio-incubators and also for establishing new generation Biotechnology Incubators with an objective to create knowledge and develop entrepreneurship in biotechnology. The focus could be on the following areas in the biotechnology sectors: Biopharma, Bioagri, Industrial Biotechnology, Bioenergy and other areas of life sciences. The Bio-incubators for SMEs and start-ups/Innovation Centre only for start-ups could be as a standalone facility or as a part of an existing University/ Institute or Park. They would cater to the requirements of start-up’s and SMEs. BIRAP invites Letters of Intent (LOI) from interested public and private academic institutions (Universities, Research Institutes) / SEZs / etc for the development of Biotechnology Incubator Projects/s. Interested Parties may download the “Project Information Memorandum”, LOI format and other required detailed information from Short listing of the LOIs would be done in two weeks based on the listed criteria and the selected participants will be informed. Subsequently a detailed proposal will have to be submitted. The last date for submission of LOI documents is 15th July, LOIs are to be submitted by with all the documents and attachments in a single file to / For further details contact: Dr. Ravi Dhar, Consultant IP cell, BIRAP ; Mr. Rajneesh Kumar, Programme Manager, Technology Transfer, BIRAP Phone Number:

23 Method Advertisement Stakeholders meet to get their inputs Screen/Shortlist : Parameters TSC meet/Shortlist Presentations Selection Site visit & Financial Due Diligence Apex committee Approval Disbursement of funds – Issue : Paper work etc/permission 17-19, March 2012ISBA_RD_BIRAC

24 Selection Criteria The proposals selected for evaluation based on the following criteria: Technical merit of the proposal Target Beneficiaries Services/facilities to be provided Respondent’s qualification in the field of the assignment. Respondent’s technical and managerial capabilities. Respondent’s core business and years in business, if any Qualifications of the respondent’s key staff that would work on this assignment specifically. Respondent’s experience in supporting businesses, notably entrepreneurs in at the national and international level , March 2012ISBA_RD_BIRAC

25 17-19, March 2012ISBA_RD_BIRAC Wet Lab space & Equipment Office Cubicles for Incubatees Admin/IT/ Security/Services /Library Food Court/ Canteen Resting space Reagents & Chemical Store

26 Issues during Project Implementation  Concept not well understood – think as funding instrument only?  Weak project writing skills  Incomplete Paper work, Approvals  Incomplete information given in proposal  Resistance of host organization to address queries raised by BIRAC  Regulatory issues 17-19, March 2012ISBA_RD_BIRAC

27 Funding - India 17-19, March 2012ISBA_RD_BIRAC The existing system of public incubators: Duration: 2-5 years Funding per project: varies; based on milestones; Funding varies Government participation: 50%-85% Ownership: Joint governance during funding; subsequently could belong to host organization!

28 Where India stands? No of Life science incubators, India : 52 mixed International Scenario: 1100 nos. U.S.A. : 12% functional France : 4% functional Germany: 32% functional India : Relatively new – growing 17-19, March 2012ISBA_RD_BIRAC

29 BIRAC National Incubators C-CAMP, Bangalore (Protein Characterization under GLP conditions for Industry) DBT_BIRAC Incubator at Alexandria, Genome Valley, Hyderabad (BTIC) NABI, Agri Bioincubator, Mohali RCB Biotech Science Cluster, Faridabad 17-19, March 2012ISBA_RD_BIRAC

30 17-19, March 2012ISBA_RD_BIRAC Regulatory Compliance Issues – Infrastructure Building G-2/G-3 issues related to building Regulatory Approvals from Pollution Board Safety norms for incubators

31 International Models Alexandria: Private Israel: Entrepreneur driven Germany: Entrepreneur driven Nottingham: Private + Public 17-19, March 2012ISBA_RD_BIRAC

32 Bio-incubators in Israel 17-19, March 2012ISBA_RD_BIRAC The existing system of public incubators: Duration: up to 2 years Funding per project: up to $350,000 Government participation: 85% Ownership: Entrepreneur - 50% Private investors - 20% Incubator - 20% Other staff members - 10%

33 Bio-incubation is a Time Consuming Process Biotech requires more time Biotech requires more funding Importance of shared infrastructure Specialized management is crucial Special mentors for incubatees 17-19, March 2012ISBA_RD_BIRAC

34 Our website: Questions? or Or 17-19, March 2012ISBA_RD_BIRAC

35 17-19, March 2012ISBA_RD_BIRAC Thank You

36 17-19, March 2012ISBA_RD_BIRAC


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