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ISBA Meeting Pune March 18, 2012

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1 ISBA Meeting Pune March 18, 2012
Bio-Incubators Ravi Dhar, Ph.D. BIRAC (previously DBT_BIRAP) ISBA Meeting Pune March 18, 2012 17-19, March 2012 ISBA_RD_BIRAC 2012

2 Acknowledgements ISBA, Dr. R. Jagdale Secretary, Prof. M. K. Bhan, DBT
Dr. Renu Swarup, DBT & BIRAP Mr. Rajneesh Kumar, BIRAP Colleagues at DBT, BIRAP, IITs Various Expert Committee Members Various stakeholders 17-19, March 2012 ISBA_RD_BIRAC 2012

3 Definition as Perceived
“A Bioincubator is a building designed for housing R&D driven companies active in Life sciences. It is mostly closely related to a neighbouring university. A Bioincubator is a Business incubator targeted towards Life Sciences helping start-up companies. Entrepreneurs with feasible projects in Life Sciences are selected and admitted into the incubators, where they are offered a specialized menu of support resources and services, including mentoring” 17-19, March 2012 ISBA_RD_BIRAC 2012

4 Bio-incubator Scenario in India
Life science (mixed) incubators: 52 N: 10 S: 27 E: 5 W: 8 Exact Classification not clear 17-19, March 2012 ISBA_RD_BIRAC 2012

5 Basic Research/Discovery
Evolution of DBT over years Basic Research/Discovery Innovation Enterprise 17-19, March 2012 ISBA_RD_BIRAC 2012

6 Basic Research/Discovery
Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Funding Support 17-19, March 2012 ISBA_RD_BIRAC 2012

7 Basic Research/Discovery
Phase-I: Basic Infrastructure/Capacity Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Funding Support 17-19, March 2012 ISBA_RD_BIRAC 2012

8 Basic Research/Discovery Incubator Space or SMEs
Phase-I: Basic Infrastructure/Capacity Phase-II: Product Development I Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Funding Support Public or Private Incubator Space or SMEs II 17-19, March 2012 ISBA_RD_BIRAC 2012

9 We need to get out of this syndrome
Phase I to II Syndrome ? We need to get out of this syndrome 17-19, March 2012 ISBA_RD_BIRAC 2012

10 Parks & Incubators DBT initiated several Parks & incubators
sometime back Definitions: Science Parks: An area usually linked with a university where scientific research and commercial development are carried on in cooperation Bio-incubators: Incubators specifically are meant to allow young incubatees / start-up companies to initiate and dabble into entrepreneurship 17-19, March 2012 ISBA_RD_BIRAC 2012

11 DBT Mandate Bio-Incubators BIRAP
Funding of various Research & Technology schemes by DBT National Biotech Policy (1997) mandated 30% funding for PPP BIRAP (=BIRAC) funded schemes: SBIRI BIPP Bio-Incubators CRS BIG Capacity Building + Training BIRAP 17-19, March 2012 ISBA_RD_BIRAC 2012

12 BIRAC Mandate Trigger, Transform & Tend- Biotech Start-ups to convert innovative research in Public and Private sector Support & Strengthen SME’s, facilitates high risk research, innovation and product development Financial, Infrastructural, Institutional & Mentoring support for budding entrepreneurs Encourage Knowledge Networking among biotech entrepreneurs at National & International Level Policy and Institutional Support for all Stakeholders in Biotech Conceptualize and Support development of affordable, novel, deployable products and technologies in Healthcare, Agriculture, Environment Bio- energy involved in PPP Promote Secondary Agriculture for providing opportunity in entrepreneurship & employment. 17-19, March 2012 ISBA_RD_BIRAC 2012

13 BIRAC Evolution It is linked to Evolution of DBT over years
17-19, March 2012 ISBA_RD_BIRAC 2012

14 National Biotechnology Development Strategy Sept., 2007
How we moved ….. National Biotechnology Development Strategy Sept., 2007 Pilot BIRAP Sept., 2008 Stakeholder Consultations, innovation support programmes, skill augmentation Approval for BIRAC Stakeholder Consultations, Future blue-print for formalization & action Section 25 Company Not-for-profit/ for public good/ Private Company Company Registered on 17-19, March 2012 ISBA_RD_BIRAC 2012

15 17-19, March 2012 ISBA_RD_BIRAC 2012

16 Basic Research/Discovery Incubator Space or SMEs
Phase-I: Basic Infrastructure/Capacity Phase-II: Product Development Evolution of DBT over years Basic Research/Discovery Innovation Enterprise Funding Support Public or Private Incubator Space or SMEs BIG Grant 17-19, March 2012 ISBA_RD_BIRAC 2012

17 An Ideal BIRAC Incubator
Building designed for housing incubatees or start-up entrepreneurs active in Life Science Presence of neighbouring academic organizations or universities or hospitals or R&D Industrial units. It therefore is a like a Business Incubator targeted towards Life Sciences helping start-ups. Entrepreneurs with feasible projects in Life Sciences are selected and admitted into the incubators as tenants, where they are offered a specialized menu of support resources and services, including mentoring. 17-19, March 2012 ISBA_RD_BIRAC 2012

18 Office Cubicles for Incubatees
Wet Lab space & Equipment Office Cubicles for Incubatees Admin/IT/ Security/ services/Library Reagents & Chemical Store Food Court/ Canteen Resting space 17-19, March 2012 ISBA_RD_BIRAC 2012

19 Who Occupies the Bio-incubator
Incubatees (fresh M.Tech/Ph.D./M.B.B.S/ etc) Parties going to be SMEs 17-19, March 2012 ISBA_RD_BIRAC 2012

20 Benefits of Incubators
Creating jobs • Building or accelerating growth of local academic and industry clusters Fostering a community's entrepreneurial climate • Technology commercialization • Diversifying local economies • • Business creation and retention • Encouraging women or minority entrepreneurship • Identifying potential spin-in or spin-out business opportunities • Community revitalization 17-19, March 2012 ISBA_RD_BIRAC 2012

21 Issues in India Seed Funding Long term Sustainability
Business Models in mind: Incubatees : generally bereft SMEs: have a strategy Technology Platform Model: (Start-ups that rent/sell their technology/product to pharma/biotech companies) (?) RIPCO Model: (Start-ups that research and develop a new product to finally license it to a big pharma/biotech company in exchange for a royalty on sales) FIPCO Model: (Start-ups that launch their own Product) NRDO model: (Start-ups that buy a “discarded” promising drug from big pharma and use their technology to bring it to market) 17-19, March 2012 ISBA_RD_BIRAC 2012

22 LOI on BIRAP Bio-Incubator
Department of Biotechnology Ministry of Science and Technology Government of India Call for Letters of Intent (LOI) For DBT-BIRAP Support for Establishing and Strengthening Bio-Incubators/Innovation Centers for Research, Innovation and Technopreneurship. Biotechnology Industry Research Assistance Programme, (BIRAP) is a programme of the Department of Biotechnology, Govt. of India, with an objective to assist and promote emerging biotech entrepreneurs and facilitate innovative research and development in existing small, medium as well as large industries. Biotech incubator acts as a catalyst that would stimulate research & develop and for creating of new biotechnology ventures/startups. In order to give thrust to the biotechnology industry in the country, DBT-BIRAP aims to provide financial support in form of soft loans and grants for Strengthening the already existing Bio-incubators and also for establishing new generation Biotechnology Incubators with an objective to create knowledge and develop entrepreneurship in biotechnology. The focus could be on the following areas in the biotechnology sectors: Biopharma, Bioagri, Industrial Biotechnology, Bioenergy and other areas of life sciences. The Bio-incubators for SMEs and start-ups/Innovation Centre only for start-ups could be as a standalone facility or as a part of an existing University/ Institute or Park. They would cater to the requirements of start-up’s and SMEs. BIRAP invites Letters of Intent (LOI) from interested public and private academic institutions (Universities, Research Institutes) / SEZs / etc for the development of Biotechnology Incubator Projects/s. Interested Parties may download the “Project Information Memorandum”, LOI format and other required detailed information from Short listing of the LOIs would be done in two weeks based on the listed criteria and the selected participants will be informed. Subsequently a detailed proposal will have to be submitted. The last date for submission of LOI documents is 15th July, LOIs are to be submitted by with all the documents and attachments in a single file to / For further details contact: Dr. Ravi Dhar, Consultant IP cell, BIRAP ; Mr. Rajneesh Kumar, Programme Manager, Technology Transfer, BIRAP Phone Number: 17-19, March 2012 ISBA_RD_BIRAC 2012

23 Method Advertisement Stakeholders meet to get their inputs
Screen/Shortlist : Parameters TSC meet/Shortlist Presentations Selection Site visit & Financial Due Diligence Apex committee Approval Disbursement of funds Issue : Paper work etc/permission 17-19, March 2012 ISBA_RD_BIRAC 2012

24 Selection Criteria The proposals selected for evaluation based on the following criteria: Technical merit of the proposal Target Beneficiaries Services/facilities to be provided Respondent’s qualification in the field of the assignment. Respondent’s technical and managerial capabilities. Respondent’s core business and years in business, if any Qualifications of the respondent’s key staff that would work on this assignment specifically. Respondent’s experience in supporting businesses, notably entrepreneurs in at the national and international level. 17-19, March 2012 ISBA_RD_BIRAC 2012

25 Office Cubicles for Incubatees Admin/IT/ Security/Services/Library
Wet Lab space & Equipment Office Cubicles for Incubatees Admin/IT/ Security/Services/Library Reagents & Chemical Store Food Court/ Canteen Resting space 17-19, March 2012 ISBA_RD_BIRAC 2012

26 Issues during Project Implementation
Concept not well understood – think as funding instrument only? Weak project writing skills Incomplete Paper work, Approvals Incomplete information given in proposal Resistance of host organization to address queries raised by BIRAC Regulatory issues 17-19, March 2012 ISBA_RD_BIRAC 2012

27 Funding - India The existing system of public incubators:
Duration: 2-5 years Funding per project: varies; based on milestones; Funding varies Government participation: 50%-85% Ownership: Joint governance during funding; subsequently could belong to host organization! 17-19, March 2012 ISBA_RD_BIRAC 2012

28 Where India stands? No of Life science incubators, India : 52 mixed
International Scenario: 1100 nos. U.S.A. : 12% functional France : 4% functional Germany : 32% functional India : Relatively new – growing 17-19, March 2012 ISBA_RD_BIRAC 2012

29 BIRAC National Incubators
C-CAMP, Bangalore (Protein Characterization under GLP conditions for Industry) DBT_BIRAC Incubator at Alexandria, Genome Valley, Hyderabad (BTIC) NABI, Agri Bioincubator, Mohali RCB Biotech Science Cluster, Faridabad 17-19, March 2012 ISBA_RD_BIRAC 2012

30 Regulatory Compliance Issues – Infrastructure Building G-2/G-3 issues
related to building Regulatory Approvals from Pollution Board Safety norms for incubators 17-19, March 2012 ISBA_RD_BIRAC 2012

31 International Models Alexandria : Private Israel : Entrepreneur driven
Germany : Entrepreneur driven Nottingham : Private + Public 17-19, March 2012 ISBA_RD_BIRAC 2012

32 Bio-incubators in Israel
The existing system of public incubators: Duration: up to 2 years Funding per project: up to $350,000 Government participation: 85% Ownership: Entrepreneur - 50% Private investors - 20% Incubator - 20% Other staff members - 10% 17-19, March 2012 ISBA_RD_BIRAC 2012

33 Bio-incubation is a Time Consuming Process
Biotech requires more time Biotech requires more funding Importance of shared infrastructure Specialized management is crucial Special mentors for incubatees 17-19, March 2012 ISBA_RD_BIRAC 2012

34 Our website: www. birapdbt. nic. in Questions. (swarup@dbt. nic
Our website: Questions? or Or 17-19, March 2012 ISBA_RD_BIRAC 2012

35 Thank You 17-19, March 2012 ISBA_RD_BIRAC 2012

36 17-19, March 2012 ISBA_RD_BIRAC 2012


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