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Gout Review 2009 Pathophysiology, Diagnosis, and Treatment Robert E. Hiltz, MD Rheumatology Group Health Associates Cincinnati, Ohio.

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Presentation on theme: "Gout Review 2009 Pathophysiology, Diagnosis, and Treatment Robert E. Hiltz, MD Rheumatology Group Health Associates Cincinnati, Ohio."— Presentation transcript:

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2 Gout Review 2009 Pathophysiology, Diagnosis, and Treatment Robert E. Hiltz, MD Rheumatology Group Health Associates Cincinnati, Ohio

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4 Choi, H. K. et. al. Ann Intern Med 2005;143: Mechanisms of monosodium urate crystal formation and induction of crystal- induced inflammation

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7 TXF-00099

8 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: foot

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10 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: knee (arthroscopy)

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12 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, ear

13 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi of the pinna, ear

14 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: olecranon bursitis

15 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hands

16 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, hand

17 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophus, hand

18 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, hands

19 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophus, finger

20 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout of distal interphalangeal joints simulating osteoarthritis

21 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hand (radiograph)

22 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hand (radiograph)

23 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Choi, H. K. et. al. Ann Intern Med 2005;143: Putative mechanisms for chronic monosodium urate-induced inflammation and cartilage and bone destruction Modified from IL-1

24 Choi, H. K. et. al. Ann Intern Med 2005;143: Putative mechanisms for chronic monosodium urate-induced inflammation and cartilage and bone destruction Modified from IL-1

25 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: foot (radiograph)

26 Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: advanced disease, foot (radiograph)


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