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Commercial awareness of bioscience industry Dr. Daria Olijnyk Sistemic Ltd.

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Presentation on theme: "Commercial awareness of bioscience industry Dr. Daria Olijnyk Sistemic Ltd."— Presentation transcript:

1 Commercial awareness of bioscience industry Dr. Daria Olijnyk Sistemic Ltd.

2 Sistemic Ltd. - Corporate overview robust microRNA profiling customised multilayered statistical and contextual analysis Venture capital-funded (2009) Product development and service company HQ and Labs - Glasgow (UK); North American Sales Office – Boston (US) broad IP portfolio of miRNA-based products Designed to identify the key miRNAs (kmiRs™) – biomarkers of phenotype, together with their underlying biological interpretation to study changes in biological systems

3 About miRNAs Non-coding RNAs Short (17-24nt), endogenous Single stranded Regulate gene expression by transcriptional silencing and/or mRNA degradation 1898 human miRNAs (miRBase v.18) Target ~60% of human genes miRNA signature is: - Reproducible - Highly conserved between species - Tissue/cell type/biological process specific - Discriminative of healthy and diseased tissue - Analytically robust - Potent in delivery of reliable biomarkers Joshi S. R., et al. MicroRNAs-control of essential genes : implications for pulmonary vascular disease. Pulmonary Circulation. 1 (3) 357-364 2011

4 Stem Cell Research Cell Therapy Bio processing SistemQC™ SistemRNA™ Drug Development About Sistemic Ltd. Methodology

5 The utility of Sistemic Methodology Cell Characterisation/Cell QC Identity markers Potency assays Purity assessment Differentiation staging optimisation/monitoring Benchmarking cell models QC of batch-to-batch consistency SistemQC™SistemRNA™ Novel, Potent and Broadly Applicable Drug Discovery Positioning/Repurposing Predictive and Investigative Toxicology Discover robust companion biomarkers

6 The utility of Sistemic Methodology Cell Characterisation/Cell QC Identity markers Potency assays Purity assessment Differentiation staging optimisation/monitoring Benchmarking cell models QC of batch-to-batch consistency SistemQC™SistemRNA™ Novel, Potent and Broadly Applicable Drug Discovery Positioning/Repurposing Predictive and Investigative Toxicology Discover robust companion biomarkers

7 About SistemQC™ Cell identity and cell model evaluation Private and confidential

8 The utility of Sistemic Methodology Cell Characterisation/Cell QC Identity markers Potency assays Purity assessment Differentiation staging optimisation/monitoring Benchmarking cell models QC of batch-to-batch consistency SistemQC™SistemRNA™ Novel, Potent and Broadly Applicable Drug Discovery Positioning/Repurposing Predictive and Investigative Toxicology Discover robust companion biomarkers

9 About SistemQC™ Adult mesenchymal stem cell discrimination Private and confidential

10 Rapid growth at Sistemic continues Commercial Sector Sales continue to grow Customer base expanded over 3 continents

11 Customer base

12 Customer Base Private and confidential

13 Rapid growth at Sistemic continues Commercial Sector Sales continue to grow Customer base expanded over 3 continents Research and Development Academic collaborations Industrial collaborations Internal R&D

14 Industrial Collaborations

15 Rapid growth at Sistemic continues Commercial Sector Sales continue to grow Customer base expanded over 3 continents Research and Development Academic collaborations Industrial collaborations Internal R&D Teaching Joined PhD studentship BSc student placements Company profile Plan to increase the number of staff Plan to move to new premises

16 Career progression FROM ACADEMIA TO INDUSTRY Becoming aware and able to identify transferable skills that you gain throughout your academic career and life experiences

17 You will be surprised... COMMUNICATION, MANAGMENT AND LEADERSHIP SKILLS Erasmus-Socrates placement proactive determination BSc in Biotechnology MRes in Biomedical and Life Sciences time management skills familiar with immunological techniques used in drug development ability to work under stress ability to meet deadlines team working skills communication skills good customer care reliability and punctuality Bar supervisor at Blanket night club Research Technician for MD Biosciences Inflammation Discovery Sciences PhD in Pubertal Mouse Mammary Gland Development Postgraduate Teaching Assistant and Tutor Mentoring Charity work broad set of project/time management skills broad set of written and oral communication skills organisation skills leadership skills team working skills and ability to work unsupervised

18 Career progression FROM ACADEMIA TO INDUSTRY Becoming aware and able to identify transferable skills that you gain throughout your academic career and life experiences Be enthusiastic, flexible and prepared to spend time learning and polishing a new set of skills needed to adapt a different way of working/carrying out research

19 I still learn every day... The way you talk about your research and results Higher level of documentation - lab book – evidence for patenting (very accurate, signed off by another person every day, be aware not to put any personal observations that may prove incorrect but may jeopardise patent application) - client sample/analysis – standardised way of recording information Experiments are carried out according to accepted/standard protocols proprietary to the company (SSOP) Another layer of communication skills – speaking to customers, company representatives, company marketing Small-medium company allows interactions with multidisciplinary team - often you will be involved in a variety of different tasks

20 Career progression FROM ACADEMIA TO INDUSTRY Becoming aware and able to identify transferable skills that you gain throughout your academic career and life experiences Be enthusiastic, flexible and prepared to spend time learning and polishing a new set of skills needed to adapt a different way of working/carrying out research Be open minded and versatile and not afraid to step out of your comfort zone “ To progress your carrier in industry you have to think about science from a broader, more managerial, business-like perspective” Jim Reid Chairman/CEO at Sistemic

21 o There is hope! Life Sciences has been identified by Government and Scottish Enterprise as a key sector for Scottish economy A lot of financial support for Life Sciences sector in Scotland Scotland - one of the largest Life Sciences clusters in Europe (560 companies) The number of jobs in Life Sciences sector are sill growing

22 Good luck! daria.olijnyk@sistemic.co.uk


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