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Sponge: Set up Cornell Notes on pg. 85 Topic: 14.2 Components of Blood Essential Questions: 1.How does a red blood cell change as it matures 2.How do WBCs.

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Presentation on theme: "Sponge: Set up Cornell Notes on pg. 85 Topic: 14.2 Components of Blood Essential Questions: 1.How does a red blood cell change as it matures 2.How do WBCs."— Presentation transcript:

1 Sponge: Set up Cornell Notes on pg. 85 Topic: 14.2 Components of Blood Essential Questions: 1.How does a red blood cell change as it matures 2.How do WBCs reach microorganisms that are outside blood vessels? 2.1 Atoms, Ions, and Molecules 14.2 Components of Blood

2 Red Blood Cell Production (1m31s) EM 2

3 Blood Cells PowerPoint Directions: Please create a 1-3 slide Powerpoint Presentation on the type of cell you are assigned. Mrs. McCobb will then grade/edit (as needed) the compilation PPT to present to the class on Thursday for notes.  Save/Export as a PowerPoint Presentation o File  Export  PPT  Next  Save as: (Title of PPT)  Where: Desktop  Export  Submit to Edmodo. Please include all group members’ names in the comment section.

4 4 Characteristics of Red Blood Cells Red Blood Cells aka erythorocytes (e-ryth-ro-cytes) biconcave discs (thinner in center). This shape: allows them to transport gases places the cell membrane closer to the O2 carrying hemoglobin allows them to squeeze through capillaries lack nuclei and mitochondria

5 5 Hemoglobin: Oxygen carrying molecule Responsible for the color of blood When O2 combines with hemoglobin, the resulting oxyhemoglobin is bright red Deoxyhemoglobin is darker Blood rich in this may appear bluish when viewed through blood vessel walls

6 RBCs and Oxygen (1m8s) 4AwpU 6

7 7 Cyanosis: A person experiencing prolonged oxygen deficiency (hypoxia) may become cyanotic The skin and mucous membranes appear bluish due to an abnormally high amount of deoxyhemoglobin Exposure to low temps may also result in cyanosis

8 8 Red Blood Cell Counts (RBCC) number of RBCs in a cubic millimeter (mm 3 )of blood 4,600,000 – 6,200,000 in males 4,200,000 – 5,400,000 in adult females 4,500,000 – 5,100,000 in children reflects blood’s oxygen carrying capacity

9 9 Red Blood Cell Production Life span: approx 120 days Will travel through the body about 75,000 times low blood oxygen causes kidneys and liver to release erythropoietin which stimulates RBC production

10 10 Green box: Erythrocytosis: a condition where an individual produces about 25% more red blood cells than normal The result… GREAT physical endurance Can be mocked by “blood doping” Eero Mäntyranta 3 Olympic gold metals Two world championships in cross country skiing

11 11 Dietary Factors Affecting Red Blood Cell Production The availability of vitamin B and folic acid significantly influences red blood cell production

12 12 Life Cycle of Red Blood Cell circulate for about 120 days macrophages in spleen and liver destroy worn out RBCs hemoglobin is broken down into heme and globin iron from heme returns to red bone marrow bilirubin and biliverdin excreted in bile

13 13 Types of Anemia

14 14 Anemia Normal RBCs RBCs of person with hypochromic anemia

15 15 White Blood Cells White blood Cells (WBC) aka Leukocytes Protect against disease Blood transports WBCs to sites of infection They can leave the bloodstream

16 16 Neutrophils first to arrive at infections phagocytic 54% - 62% of leukocytes elevated in bacterial infections

17 Neurtophils (2m14s) AaQ 17

18 18 Eosinophils moderate allergic reactions defend against parasitic worm infestations 1% - 3% of leukocytes elevated in parasitic worm infestations and allergic reactions

19 19 Basophils Migrate to damaged tissue release histamine which promotes inflammation release heparin which inhibits blood clotting (increasing blood flow to injured tissue) less than 1% of leukocytes

20 20 Monocytes largest blood cell leave bloodstream to become macrophages 3% - 9% of leukocytes phagocytize bacteria, dead cells, and other debris

21 21 Lymphocytes Two types: T cells directly attack microorganisms B cells produce antibodies which will attack foreign molecules 25% - 33% of leukocytes

22 Types of WBCs and Their Functions (4m38s) U8S6ZMk 22

23 23 Diapadesis Diapadesis: leukocytes squeeze between the cells of a capillary wall and enter the tissue space outside the blood vessel (leave circulation) Functions of WBC: to protect against infection in various ways

24 24 Positive Chemotaxis movement of leukocytes toward the damaged tissue region because of the chemicals that were released by damaged cells

25 Diapedesis and Chemotaxis KzKs 25

26 26 White Blood Cell Counts Normal: 5,000 – 10,000 per cubic millimeter of blood leukopenia low WBC count (below 5,000) typhoid fever, flu, measles, mumps, chicken pox, AIDS, may come from anemia, lead, arsenic, or mercury poisoning. leukocytosis high WBC count (above 10,000) acute infections, appendicitis May follow vigorous exercise, emotional disturbances, great loss of body fluids Differential WBC count may indicate infections: lists percentages of types of leukocytes may change in particular diseases

27 27 White Blood Cell Counts

28 28 Blood Platelets aka thrombocytes They are not complete cells (cell fragments of megakaryocytes) 130,000 – 360,000 per cubic millimeter of blood helps control blood loss from broken vessels

29 29 Blood Plasma straw colored liquid portion of blood makes up 55% of blood plasma is 92% water

30 The Blood Typing Game icine/bloodtypinggame/ Or Google: Nobel Prize Blood Typing Game 30


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