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Lab Animal Clinical Management. Extra Credit Please explain your position on biomedical research and the use of animals in this field the more effort.

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Presentation on theme: "Lab Animal Clinical Management. Extra Credit Please explain your position on biomedical research and the use of animals in this field the more effort."— Presentation transcript:

1 Lab Animal Clinical Management

2 Extra Credit Please explain your position on biomedical research and the use of animals in this field the more effort you put into this, the more credit will be awarded THERE IS ABSOLUTELY NO PENALTY FOR HAVING A SEPARATE OPINION than my own. Please Please explain how you feel and why. written form is due Wednesday 3/5/14

3 research - careful, patient, systematic, diligent inquiry or examination in a field of knowledge. undertaken to establish facts or principles human life expectancy yrs

4 Disease (USA) in millions 61.8 cardiovascular 50 hypertension 24 hearing disorders 20.5 cataracts 17 diabetes 0.7 leukemia 0.7 lymphoma 14 alcoholism 40.5 arthritis 4 Alzheimer’s 2 schizophrenia 0.4 MS SIDS

5 Biomedical Research area of science to investigate a biologic process or disease comparative anatomy this information is used to discover or advance any area of medicine (including medications, surgical procedures, treatments/therapy) Prevent/Treat/Cure Disease in Animals and Humans

6 Polio by 1960 BMR had developed a vaccine and nearly irradiated the disease Antibiotics, Small Pox, Measles, Bone Marrow Transplants, Open-Heart Sx, pet meds/vax, human OTC, Rabies to name only a few - current research is moving toward improved treatments and cures for cancer, Avian Flu, Ebola, AIDS children outside of Third World Countries receive a polio vaccine in addition to typhus, diphtheria, whooping cough, smallpox, and tetanus Diabetes

7 canine population was struck suddenly with worldwide outbreak of severe vomiting, diarrhea (dehydration) and frequent death

8 Parvo (similar to feline panleukopenia) - canine vaccine tested, approved, and produced within 1 year also FeLv, FIV

9 table 1.1 pg 3 biomedical breakthroughs

10 husbandry nutrition behavior health reproduction herd health we must understand how to identify and treat stress and discomfort in the scope of the protocol

11 biotechnological advancement genetic-engineering FDA EPA Consumer Product Safety Commission (CPSC) OSHA cruelty-free products - either indirectly tested or just plain untested - blindness, a med with a heinous side-effect

12 Where Universities Hospitals Pharmaceuticals Farms VTI

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21 AALAS Myth Slides 5-12

22 AALAS Jobs 28-38

23 Independent Study Regulations - very straight forward, no room for interpretation. You will be responsible for the following information come test time Animal Welfare Act Animal Welfare Information Center GLP pg 18 Public Health Service The Guide IACUC AVMA OLAW

24 despite all my rage…

25 Euthanasia

26 95% of studies end in euthanasia AVMA Guideline for Humane Euthanasia VTI

27 The protocol dictates which animals will be euthanized and at what point. This protocol is approved by the IACUC long before an animal is ever involved. It also details how euthanasia is to take place and who is responsible for this procedure (depending on samples that may need to be taken following euthanasia)

28 methods CO 2, Euthanex chamber Injectable YOU MUST BE TRAINED TO DO THIS

29 Adoption Sanctuary - Chimp Haven, Bastrop, Retirement Sanctuary for Laboratory Animals

30 Enrichment/Stress absolutely paramount on the part of the animal care staff. at minimum it affects research the effects of stress must be controlled or the data is useless parturition, breeding, serum chems, eating, enrichment, training, and the list goes on

31 enrichment

32 Animal Rights vs Animal Welfare

33 cruel - VTI? dispassionate - proof? PETA - importance? animal rights vs animal welfare Sarah McLachlan

34 Replace Reduce Refine

35 the stereotypical rights activists does not believe in kenneling dogs zoos/aquariums food animals abstain from Western medicine broken hand, OTC meds, x-rays, sx, prosthetics Sarah McLachlan - distortion of facts

36 Kill vs Euthanize Pets? Welfare - the physical and psychological needs of the animals are paramount - the welfare of a biomedical research animal are directly proportional to the welfare of mankind

37 there is a perspective that paints BMR as painful and torturous. the vast majority of procedures are non-painful for the animals and the other are treated appropriately by the veterinary team with analgesia and swift euthanasia PRN these animals may experience disease in an effort to prevent or cure human disease

38 PETA vs AMA - funding, public opinion always remember the 3 Rs

39 extremists violent threats to doctors and staff at better- publicized institutions. labs are broken into, animals are stolen, equipment and data is destroyed worst case scenarios have involved violence and bombings


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