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Unit 5: Reproduction Male Reproductive System Female Reproductive System.

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Presentation on theme: "Unit 5: Reproduction Male Reproductive System Female Reproductive System."— Presentation transcript:

1 Unit 5: Reproduction Male Reproductive System Female Reproductive System

2 Epididymis Scrotum Testis Vas deferens Cowper’s gland Seminal Vesicle Prostate gland Ejaculatory duct Urethra Penis Bladder The scrotum regulates the temperature of the testes. Sperm form best at 35 o C. Label the following diagram Glans Prepuce (Foreskin) Rectum

3 Label the following diagram Vas deferens Vasa (ductus) deferentia Cowper’s gland Seminal Vesicle Prostate gland Urethra Bladder Link with pictures Ureter (carries urine from kidney to bladder) Epididymis Testes

4 Test Yourself 1.Vas Deferens 2.Seminal Vesicles 3.Prostate gland 4.Cowper’s gland 5.Epididymis 6.Testis 7.Scrotum 8.Penis 9.Pubic Bone 10.Bladder 11.Urethra

5 Male Testes Sertoli Cell Sperm Nourishes sperm, secretes inhibin, spermatogenesis, stimulated by FSH and testosterone Vas deferens epididymis Seminiferous Tubules Follicle (2n) Wall of Seminiferous tubule sperm Developing Follicles (n) Interstitial Cells In between seminiferous tubules. Produce testosterone Where sperm are made

6 Testes- sperm formation Follicle

7 Contain: 1.Sertoli Cells (in seminiferous tubules) Secrete chemicals required for the nourishment and development of sperm cells Responsible for spermatogenesis. Protection from man’s immune system Produce inhibin hormone to slow sperm production Influenced by FSH (follicle stimulating hormone) from pituitary and by testosterone from interstitial cells. 2. Interstitial Cells (b/w seminiferous tubules) Produce testosterone Influenced by LH (leutinizing hormone) from the pituitary Testes Sertoli cells in Seminiferous tubules Interstitial cells

8 3. sperm 2. follicles 1. Interstitial cells 4. Sertoli cell Meiosis Diagram from Diploma Exam

9 Sperm Head Acrosome and nucleus (23 chromosomes) Middle Mitochondria for energy Tail Flagellum for swimming Contains an enzyme to penetrate layers surrounding the ovum Watch sperm swim Life span of a sperm cell: In the epididymis - many years In semen – at body temperature, 1-5 days Stored at -100 o C - many years

10 Pathway of Sperm The Great Sperm Race The Great Sperm Race Vas deferens Ejaculatory duct Testes Epididymis Vas deferens Ejaculatory Duct Urethra Epididymis

11 Scrotum and Epididymis Epididymis - storage and maturation of sperm - the immune system destroys the “bad” sperm - develop a flagellum to swim. Scrotum - Skin and muscle covering the testes - Allows sperm to develop at optimal temperature (35 o C) Scrotum

12 Vas Deferens and Ejaculatory Duct Vas deferens Ejaculatory duct Ductus (Vas) Deferens – carries sperm from epididimus-> ejaculatory duct Ejaculatory Duct -regulates the movement of semen into the urethra. (A sphincter regulates the removal of urine from the bladder.)

13 Penis and Urethra Urethra - carries semen (reproductive system) and urine (excretory system).

14 Seminal Fluid Secreted by Accessory Glands: Cowper’s gland Seminal Vesicle Prostate gland Student Price Card an acronym to remember the order

15 Seminal Fluid (Semen) Cowper’s gland Seminal Vesicle Prostate gland 1) Seminal vesicles - 60% of total fluid Contains fructose for energy and Prostaglandins which cause rhythmic contractions of the smooth muscles in female, which help sperm move up the uterus.

16 Seminal Fluid (Semen) Cowper’s gland Seminal Vesicle Prostate gland 2) Prostate gland : -alkaline buffer and mucus that protects sperm against acidic environments in the urethra and the vagina. -Increases mobility of sperm

17 Prostate Cancer Prostate gland Prostate cancer – Due to genetics, diet and lifestyle. Symptoms: Difficulty urinating, blood in urine, erectile dysfunction. Diagnose with a rectal exam. (Start testing at ~age 40.)

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19 Seminal Fluid (Semen) Cowper’s gland Seminal Vesicle Prostate gland 3) Cowper’s gland : -Secretes a mucus and alkaline buffer prior to ejaculation -protects against acid in urine and increases mobility. -May contain sperm (reason for high failure rate of withdrawal method) Sperm + seminal fluids = semen

20 Semen Cowper’s gland Seminal Vesicle Prostate gland In one ejaculate there is about 3 – 4 mL of fluid and about 40 – 100 million sperm cells per mL (Note: at least a few dozen must reach the egg to ensure fertilization!)

21 Penis Dilation of the arteries (erection) of the penis is under the influence of the parasympathetic nervous system. Delivers semen to female vagina Arterioles dilate  increase blood flow  Fills with blood to become erect Compresses veins that carry blood away from penis  pressure builds  erection

22 Ejaculation is accomplished by the contraction of the vas deferens, the prostate and the muscles at the base of the penis, under the influence of the sympathetic nervous system. Ejaculation : the release of semen through the urethra Refractory period: period of time that must pass prior to a second erection. The Great Sperm Race

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25 Because for both you just Point and Shoot... PP P oint = P arasympathetic… controls erections SS S hoot = S ympathetic controls ejaculations How is a penis like a camera?

26 Impotency Impotency: inability to produce or maintain an erection. Possible causes: - hormone imbalance - problem with parasympathetic nerves (damage) -drugs / alcohol / smoking -Stress

27 Puberty in boys Puberty is when the reproductive system completes its development and becomes fully functional Puberty begins when the hypothalamus begins releasing gonadotropin releasing hormone (GnRH) GnRH acts on the anterior pituitary to produce FSH and LH Puberty begins

28 Hormonal Control Testosterone - stimulates: spermatogenesis primary characteristics (reproductive organs) secondary characteristics (deepening of voice, facial and pubic hair, muscle growth) Inhibin – produced by the Sertoli cells to inhibit FSH production which slows sperm production Brain Master Gland

29 Hypothalamus (GnRH) Anterior pituitary FSHLH Sertoli cells Interstitial Cells Testosterone Sperm production inhibin _ _ Testis Draw it!

30 Andropause Decline in testosterone production in men –Happens around age 40 Results in depression, fatigue, drop in sperm production, and loss of muscle and bone mass Treatment: testosterone supplements, exercise

31 Male Reproductive System Mini-Review 1. Arrange the following structures in the order that sperm passes through them: 1. vas deferens 2. urethra 3. epididymis 4. seminiferous tubules 5. ejaculatory duct 3. epididymis 4. seminiferous tubules (within testes – not visible here) 1. vas deferens 5. ejaculatory duct 2. urethra 4, 3, 1, 5, 2

32 Male Reproductive System Mini-Review 2. What is the significance of the acrosome of the sperm? A: The acrosome contains enzymes needed to help the sperm penetrate through the protective layer surrounding a female egg

33 Male Reproductive System Mini-Review 3. What is the difference between interstitial cells and Sertoli cells? Interstitial cells: -Located between seminiferous tubules -Secrete testosterone Sertoli cells: -Located inside seminiferous tubules -Nourish and support developing sperm -Responsible for spermatogenesis -Release inhibin

34 Male Reproductive System Mini-Review 3. Where are sperm made? Seminiferous Tubules -Follicle cells are stimulated by the sertoli cells to undergo meiosis.

35 Label the following diagram ovary fallopian tube (oviduct) fimbriae uterus cervix ureter vagina urethra labium minora bladder clitoris labium majora

36 Label the following diagram Cervix (opening of uterus) Endometrium (uterine lining) fallopian tube (usual site of fertilization) Ovary (oogenesis, estrogen and progesterone) Fimbriae (catches the egg) Vagina (birth canal) Uterus (usual site of implantation)

37 Ovaries – site of oogenesis Females have 2 ovaries, which alternate each month to produce an egg/ovum (oogenesis). ovary Fallopian tube Follicles: ovum (egg) (female gametes) & accessory cells (“Granulosa cells”), secrete estrogen Corpus luteum: secretes hormones (Estrogen & Progesterone). Ovaries contain ~ 400,000 egg cells, but only ~ 400 actually mature between the ages of 12 – 50.

38 Ovum (egg) The ovum lives for 24 hours after ovulation. The egg is larger than sperm because the cytoplasm in the egg has to provide enough nutrients for 5 days if the egg is fertilized. Ovary sperm NOVA: The Egg’s Journey

39 Ovulation - When a follicle matures, it ruptures, releasing the ovum Fimbrae - picks up ovum from ovary (finger-like extensions of fallopian tube) Fallopian tube (Oviducts) passage from ovary to uterus; site of fertilization ovary Fallopian tube Fimbriae

40 Uterus Uterus – site of embryo development, two layers: –endometrium – nourishes embryo; shed during menstruation; blood vessel rich –Myometrium – muscular layer Cervix – muscular opening to uterus –cells constantly shed and replaced Vagina – entrance for the penis as well as birth canal Uterus vagina cervix Endometrium A pap smear checks for changes in the cells of the cervix. Changes may indicate infection, unhealthy cervical cells, or cervical cancer (can be caused by HPV(genital warts).

41 Fertilization and Implantation Pathway for sperm: 1.vagina 2.cervix 3.uterus 4.Fallopian tube Fallopian tube Uterus cervix vagina Fertilization usually occurs in the fallopian tubes and implantation occurs in the uterus.

42 Puberty in Girls At puberty, the hypothalamus releases gonadotropin releasing hormone (GnRH) GnRH activates the anterior pituitary to release FSH and LH FSH secretions are carried by the blood to the ovary where follicle development is stimulated. The follicles within the ovary secrete estrogen into the blood which stimulates the development of the secondary female characteristics: breasts, hair, wider hips.

43 Female Reproductive Goals 1.Develop follicle (egg) 2.Develop Endometrium 3.Ovulate 4.Fertilize and Implant 5.Maintain Corpus Luteum and Endometrium –(or shed to reset for next month) This is all accomplished via horomonal control!!!!!!!!

44 Oogenesis: female meiosis! Begins before birth in ovaries… 1 oogonia (2n)  differentiates into 1 primary oocyte (2n)  Meiosis I stops at Prophase I until puberty After puberty… Each month, 1 primary oocyte finishes Meiosis I  1 secondary oocyte (1n) & 1 polar body (1n)  Ovulation: secondary oocyte to fallopian tubes IF fertilized… secondary oocyte (1n)  Meiosis II  1 Ovum (1n) & 1 polar body

45 follicles Ovum (n) Ovum released – ovulation (day 14) Corpus luteum LH Progesterone and estrogen FSH Menstrual Cycle Immature follicles (2n) Estrogen From pituitary: ~28 days long Meiosis II occurs in fallopian tube if fertilized Order of hormones: FELP

46 Hormones of the Menstrual Cycle GnRH: stimulated by high levels of E, inhibited by high E & P, causes FSH/LH release FSH: promotes follicle growth LH: promotes ovulation, corpus luteum formation  E & P production

47 Hormones of the Menstrual Cycle High E & P: promotes growth of endometrium, inhibits menstruation, inhibits GnRH  inhibits FSH/LH  inhibits follicle growth & ovulation decrease of E & P triggers menstruation

48 Hormones of the Menstrual Cycle hCG (“human chorionic gonadotropin hormone”): hormone secreted by embryo; prevents corpus luteum breakdown  allows E & P to stay high pregnancy test: checks hCG in urine

49 Hypothalamus (GnRH) Anterior pituitary FSHLH Follicle Corpus luteum Progesterone and estrogen Estrogen (-) For FSH Ovary Draw it! (+) For LH (-) For FSH & LH

50 Menstrual Cycle: ~28 days 1. Flow phase (Day 1-5) endometrium is shed; follicle growth in ovary Estrogen and progesterone levels are low Flow Phase

51 Menstrual Cycle: ~28 days 2. Follicular phase (Days 6-13): follicles grow and mature  secrete Estrogen endometrium thickens Stimulates GnRH & LH Follicular Phase

52 Menstrual Cycle: ~28 days 3. Ovulation (Day 14): LH peaks causing secondary oocyte to burst from the follicle in the ovary into oviduct Ovulation

53 Menstrual Cycle 4. Luteal Phase (Day 15-28) LH causes corpus luteum to develop from follicle  corpus luteum secretes E&P Endometrium thickens and is maintained (progesterone prevents contractions) Inhibits GnRH, LH & FSH (negative-feedback) Luteal Phase

54 Menstrual Cycle: ~28 days Label the hormones: FELP LH 4.

55 M ENSTRUAL C YCLE A NIMATIONS 1)http://wps.prenhall.com/wps/media/obj ects/1115/ /36_1_7a_plain.htmlhttp://wps.prenhall.com/wps/media/obj ects/1115/ /36_1_7a_plain.html 2)http://wps.prenhall.com/wps/media/obj ects/1115/ /36_2_1a_plain.htmlhttp://wps.prenhall.com/wps/media/obj ects/1115/ /36_2_1a_plain.html

56 Hormone Review 1. FSH Target: follicles in the ovary Effect: Egg and estrogen 2. Estrogen Target: various cells, endometrium, hypothalamus Effect: development of 1 o (reproductive organs) and 2 o sexual characteristics (higher voice, larger hips); neg. feedback to decrease FSH; positive feedback to increase LH production; growth of endometrium (+) LH(-)

57 Hormone Review 3. LH Target: follicle (ovulation) corpus luteum Effect: ovulation and progesterone and estrogen production 4. Progesterone Target: endometrium and hypothalamus Effect: thicken and maintain endometrium (inhibit contractions); negative feedback to stop FSH and LH (+) LH (-)

58 Ovary Estrogen LH from pituitary Progesterone and estrogen FSH From Pituitary Corpus luteum Follicles Ovulation 2n n Ovum

59 X = _______ W = ______ Z = _______ Y = _______ Hormones Controlling Menstruation FSH Estrogen LH Progesterone

60 Degernating corpus luteum

61 1. The loss of the endometrium (a monthly occurrence during the reproductive phase of a female’s life) is termed ___________ and occurs over approximately ____ days. menstruation The endometrium is shed on a monthly basis but the immediate reason is because of : Low estrogen and progesterone.

62 Progesterone & estrogen drop 3 times stimulating 3 menstruations

63 The numbered blocks represent hormones. Which hormone corresponds to each number? 1.______ 2.______ 3.______ 4.______ LH Progesterone Estrogen FSH

64 Which color represents which hormones? Estrogen Progesterone LH FSH Blood Concentrat ion of Menstrual Hormones

65 Answer the questions in your workbook using the following picture Which phase is dominated by estrogen?______________ Which phase is dominated by progesterone? _____________ The sharp rise in temperature signals what event?______________ follicular luteal ovulation

66 Draw the ovary and label it

67 Menstrual Cycle: If pregnancy does not occur Estrogen and Progesterone levels drop Endometrium lining is shed Bleeding occurs - menstruation

68 1. Predict, with a sketch, what each diagram/graph should look like if a woman were to become pregnant at around day 21. Day 45 For the first 3 months stimulated by hCG Estrogen and Prog. cause growth of the endometrium Progesterone prevents contractions Endometrium forms part of placenta

69 Menopause Occurs at around ~50 Ova are no longer produced This changes hormone production as well Symptoms: hot flashes, high cholesterol and decreasing bone mass Hormone replacement therapy – women are given low doses of estrogen (some progesterone) –But this has many side effects. Complete the Menstrual Cycle Assignment

70 Meiosis in Males and Females Males - Spermatogenesis Location : testes Females - Oogenesis Location: ovaries 2N NN NNN 4 equal sperm Meiosis 1 Meiosis 2 Follicle N 2N N N N NNN Follicle Meiosis 1 1 egg and 3 polar bodies Egg (ovum) gets most of the cytoplasm. Polar bodies die and are absorbed by body. Meiosis 2

71 150 – 300 million sperm travel though the cervix to the uterus. 100 – 500 sperm reach the oviducts Recall - egg has large cytoplasm, sperm very little cytoplasm. The cytoplasm of the egg has to nourish the zygote for approximately ________ 5 days

72 n n 2n fertilization Meiosis II In the Fallopian Tube


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