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The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges Singapore December 2013 Bijan Dorri.

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Presentation on theme: "The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges Singapore December 2013 Bijan Dorri."— Presentation transcript:

1 The two Valleys of Death in Technology Commercialization IEEE Life Sciences Grand Challenges Singapore December 2013 Bijan Dorri

2 Outline Product Development StepsProduct Development Steps Two Valleys of DeathTwo Valleys of Death Real Life ExamplesReal Life Examples GuidelinesGuidelines

3 Step 1 - Technology Development : Retiring Technical Risks Basic Research Discovery Invention Doing it Once! – Prototype

4 Step 2- Product Development : Retiring Produciblity & Regulatory Risks Detail Design Manufacturing & Supplier Development Clinical Trials Regulatory Approvals Can Make Many & Has Permission to Market

5 Step 3- Commercialization: Retiring Market Risks Market Validation Market Creation Re-imbursement Profitable Product

6 Basic Research Discovery Patenting Valley of Death 1 Product Design Clinical Trials Product Development Regulatory Valley of Death 2 Technology Development Market Creation Re-imbursement Technology Development Product Development Commercialization Two Valleys of Death

7 5 Real Life Examples MR Surgery Breast Tomosynthesis Limb MRI 64 Slice CT Cardiac CT Unmet Clinical Need Immediate Market No DV1 or 2 Replacing Existing Product 10 Years in DV2 Replacing Existing Product 20 Years in DV2 Changing Clinical Practice Died in DV2 Pocket Ultrasound New Clinical Utilization of Existing Product Tech Died in DV1 Going through DV

8 Technology Portfolio Management Market Risk Technology Risk Pocket Size Ultrasound New Detector for CT New SW for Clinical Decision Affordable Accessible ECG

9 Investment Guidelines Innovation Type Solves Unmet Clinical Need Under the hood of existing product Replaces Existing Product Changes Clinical Practice DV1 $ $$ DV2 $ 0 $$ $$$


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