Presentation on theme: "Recombinant DNA Sea slugs. What would you do? One day your brother or sister or friend is peeing a lot. They’re also really thirsty. What would you say?"— Presentation transcript:
What would you do? One day your brother or sister or friend is peeing a lot. They’re also really thirsty. What would you say? Okay so then they’re still peeing and drinking a lot of water all week and then they complain of blurred vision and they’re breath starts to smell like acetone (nail polish remover). What do you do? The doctor tells you they have diabetes.
Diabetes If you have diabetes your body doesn’t make insulin. Insulin tells cells to absorb sugar and burn it for energy. Without sugar to burn your body uses fat while the sugar lies around in the blood causing problems.
Where does the insulin come from? We used to get it from animals but animal insulin isn’t exactly human insulin and side effects like rashes would happen. In 1978 a company started using E. Coli Bacteria that has recombinant DNA in it that makes it make insulin for us like a little insulin factory.
Where’s the money? One major supplier of insulin isEli Lilly Fortune 500 corporation, revenues of $14.6 billion in 2005, 148th largest company in the U. S. prozac, cialis, and were the first to distribute methadone as an alternative for heroin users trying to quit.
Who else makes Insulin Other major distributor is Novo Nordisk H.Q. in Denmark, production facilities in six countrieswith affiliates or offices in 68 countries. Employs 22500 people globally (as of 2005) and had a turnover of 33.8 billion Danish kroner in 2005 (EUR 4.5 billion). They made 920 mil in 2004.
Recombinant DNA an artificial DNA sequence resulting from the combining of two other DNA sequences in a plasmid. Plasmids are little chunks of DNA that copy themselves. Recombinant proteins are proteins that are produced by different genetically modified organisms following insertion of the relevant DNA into their genome. As this recombines the DNA of two different organisms, the word recombinant is used to refer to this process.
What are sea slugs? Molluscs without the shell Interesting defense ability: to eject their sticky intestines out onto predators which grosses them out. Also have stigners Some of the most colorful creatures on earth
Recently the people who make insulin were trying to use recombinant DNA in other animals and they found that these Krotecus Snails could remove human waste from water in a matter of weeks.
If you work at Eli Lilly as a scientist what will you have to do before you can go to someone and convince them to spend money on this? Use the scientific method. –Observe, form a hypothesis with a prediction as to how your experiment will credit or discredit your hypothesis, experiment, collect data, analyze data, accept or reject your hypothesis and let people know about it.
How do we know they’re alive? Students will make a list of the properties that all living things share. Students will share the list and the instructor will write what they suggest on the board.
Properties of living things Organization & Cells, Respond to stimuli in environment, Homeostasis, Metabolism, Growth & Development, Reproduce. Change over time or evolve.
How do you know you can trust this claim? Critical thinking Use baloney detection