Presentation on theme: "Procedural Sedation for Clinicians"— Presentation transcript:
1 Procedural Sedation for Clinicians Barnes-Jewish HospitalInitial AppointmentDeveloped 5/2008
2 Learner Outcomes: * State the definitions of sedation according to JCAHO * Describe what patient response is expected for each degree of sedation * List appropriate pre-procedural patient assessments. * List the ongoing assessments, which should be monitored during the procedure. * List the common complications of Procedural Sedation * Discuss the management of the common complications. * Explain what is included in the post-procedural care. * Explain the evaluation for patient discharge from the interventional area/hospital. * Describe components of an airway assessment. * Identify appropriate medications for Procedural Sedation, considering patient-specific characteristics. * Outline the role for reversal agents used to reverse sedatives and describe the required monitoring parameters.
3 What is Procedural Sedation? Procedure (n) A series of steps taken to accomplish an end. Examples: EGD, bronchoscopy, fracture/dislocation reduction, cardiac catheterizationSedation (n) Reduction of anxiety, stress, irritability, or excitement by administration of a sedative agent or drug.Procedural Sedation (n) Reducing anxiety or stress with medications in order to perform a procedure. These medications may include, but are not limited to Opiates (e.g., morphine, fentanyl) and Benzodiazepines (e.g., midazolam, lorazepam).
4 Definitions: Four Levels of Sedation and Anesthesia (per JCAHO) Minimal sedation (anxiolysis) A drug‑induced state during which patients respond normally to verbal commands. Although cognitive function and coordination may be impaired, ventilatory and cardiovascular functions are unaffected; Patient is fully responsive. Description per Richmond Agitation-Sedation Scale: Briefly awakens with eye-contact to voice, >10 seconds
5 Moderate sedation A drug‑induced depression of consciousness during which patients respond purposefully to verbal commands, either alone or accompanied by light tactile stimulation. No interventions are required to maintain a patent airway, and spontaneous ventilation is adequate. Cardiovascular function is usually maintained; * Stable vital signs, intact airway. * Patient responds to verbal stimulation - may utilize light touch to support verbal stimulation. * Patient follows simple commands Description per Richmond Agitation-Sedation Scale: Movement or eye-opening to voice, (but no eye contact) < 10 seconds
6 Deep sedation. A drug‑induced depression of consciousness during which Deep sedation A drug‑induced depression of consciousness during which patients cannot be easily aroused but respond purposefully following repeated or painful stimulation. The ability to independently maintain ventilatory function maybe impaired. Patients may require assistance in maintaining a patent airway and spontaneous ventilation may be inadequate. Cardiovascular function is usually maintained; * Patient only responds to repeated or painful stimulation. * Patient does not follow commands, but may move spontaneously. * Respiratory depression is possible: may include decreased respiratory rate and/or difficulty maintaining an open airway. * BP / pulse remain stable. Description per Richmond Agitation-Sedation Scale: No response to voice, but movement or eye opening to physical stimulation
7 Anesthesia Consists of general anesthesia and spinal or major regional anesthesia. It does not include local anesthesia. General anesthesia is a drug‑induced loss of consciousness during which patients are not arousable, even by painful stimulation. The ability to independently maintain ventilatory function is often impaired. Patients often require assistance in maintaining a patent airway, and positive pressure ventilation may be required because of depressed spontaneous ventilation or drug‑induced depression of neuromuscular function. Cardiovascular function may be impaired. * Depression of life sustaining functions (may include respiratory depression and/or change in BP and pulse) * No patient response to stimulation, even painful stimulation. Description per Richmond Agitation-Sedation Scale: No response to voice or physical stimulation
8 Sedation Continuum Moving from one state of conscious to another is a dose-related continuum that depends on patient response NOT type, dose or route of medication, or any other external factors..
9 The person monitoring the patient and/or the person performing the procedure must be prepared and competent to treat one level lower than the anticipated sedation level. The most common indication patient may be beyond moderate sedation into deep sedation is respiratory depression. If the patient develops significant respiratory depression, the clinician and assistant must be prepared to support the paitent’s airway through oral/nasal airways and bag-mask ventilation. In addition, the clinician must be prepared for insertion of a definitive airway: for example, endotracheal intubation or laryngeal mask airway.
10 Which of the following notation by the Assistant would best indicate your patient’s sedation is maintained at a moderate sedation level? A. Opens eyes to sternal rub B. BP 128/68 C. Follows simple commands D. RR remains 14-16Question 1Answer: C
11 Within 5 minutes of the end of the procedure, your patient is snoring loudly and occasionally appears to have sleep apnea. When you vigorously shake his shoulder and call his name loudly, he arouses and takes a deep breath. This description most accurately describes which of the following? A. Anxiolysis B. Moderate sedation C. Deep sedation D. General anesthesiaQuestion 2Answer: C
12 Question 3You have given Ms Gray Midazolam 3 mg IVP and Morphine 2mg IVP. She remains alert but states she feels more relaxed. Select the level of sedation this patient has received. A. No sedation B. Light sedation (Anxiolysis) C. Moderate sedation D. Deep sedationAnswer: B
13 What is an indication your patient may be dropping from moderate sedation to deep sedation? A. BP drops from 128/62 to 118/56 B. SpO2 drops from 99% to 90% C. Apnea develops D. The patient squeezes your hand on commandQuestion 4Answer: B
14 Oral Intake Guidelines Age does not matter – what they took orally is the issue.Ingested Material Minimum Fasting PeriodClear Liquids hoursBreast Milk hoursInfant Formula hoursNon-clear Liquids hoursLight Meal hoursOptions for the patient not within these guidelines:Cancel the ProcedurePostpone the Procedure
15 Emergent ProceduresEmergent Procedures are life- or organ (i.e., CNS) saving procedures (consult anesthesiology)Urgent procedure are those which need to be done in 2-4 hrsDocument why it is urgent;Assess the need for sedation and preferably administer none;Consider postponing, or consult anesthesiologyMonitor the patient's airway closely, andLook for active or silent regurgitation and aspiration.
16 Risk AssessmentRisk Assessment: ASA PS (physical status) classificationASA PS correlates with overall riskNeeds to be used as a tool along with other factors such as type of procedure, medications, clinician comfort / skills“E” is added to the ASA PS number when the procedure is done on an emergency basis This indicates there is an increased risk due to the emergence of the patient’s condition, preparation or required procedure.
18 ASA PS (physical status) classification continued
19 ASA PS (physical status) classification continued
20 Informed Consent * The person performing the procedure (clinician) is to review objectives, risks, benefits and alternatives of Procedural Sedation (informed consent) * This can be done at the same time as the procedure is explained * Informed consent for the sedation does not require a patient signature. Rather there is a check box on the Pre-Procedure/Pre-Sedation Assessment form. If paper forms are not available, it is the responsibility of the clinician to document this in the pre- procedure note. * If the person who will monitor the patient (assistant) finds that the patient has additional questions, the person performing the procedure (clinician) will be contacted to answer these questions before sedation is given.
21 Responsible Individual for discharge planning The person who will provide the patient’s ride home and be available to the patient after the procedure will be identified before the procedure begins.This person may be an adult, or someone in their late teens that the patient feels comfortable with.If the patient is an outpatient, this person frequently accompanies the patient to the hospitalIf the responsible individual is not present, hospital staff need to verify the individual by telephone.If the patient is an inpatient, it may not be necessary to identify this individual pre-procedure.If the inpatient is discharged within 24 hours of the procedure, the patient must be discharged to a responsible individual.
22 Responsible individual? For outpatients: If either the clinician (person performing the procedure) or the assistant (person monitoring the patient) feels the individual present would not be appropriate in this role, or the patient has no one identified, the clinician needs to determine:Can the procedure be cancelled (or postponed) until a responsible individual is available?Should the procedure be completed and the patient kept an additional 4 hours after discharge criteria are reached, then released with appropriate transportation?
23 Discharge to Responsible Person Guidelines:Best Practice: Patient accompanied by Responsible AdultIf no responsible adult present at patient admission, staff shouldVerify via phone the responsible adult who will be present at dischargeOrIdentify a responsible individual to whom the patient can be reasonably transported after the procedureCancel the Procedure!How do I know the person is responsible?Use your professional judgment.If no responsible adult present after the procedure is completed, observe the patient for 4 hours after completion of the recovery period, then discharge (patient must not drive for 24 hours after sedation).
24 Pre-Procedure/Pre-Sedation Assessment form (required for all procedural sedation) includes documentation of the following: Review of Systems: * Can be completed by nursing or medical staff. If completed by nursing, must be reviewed by the clinician completing the pre-procedure assessment. Focused Assessment: * Must be completed by a licensed independent practitioner according to Medical Staff Bylaws. It includes procedure-specific parameters, and addresses any new or pertinent data seen on the Review of Systems. Airway Assessment: * Aim is to plan for airway management if that would be necessary. * Assessment parameters may include * Assessing dentures, loose teeth, partials, etc. * When the patient opens his/her mouth, how easily can the cords and pharynx be visualized should intubation be necessary. * Are there physical limitations, which would impede proper positioning should intubation be necessary, such as kyphosis, short neck, etc.
25 Pre-Procedure/Pre-Sedation Assessment form (required for all procedural sedation) includes documentation of the following: Risk Assessment (ASA PS Score) * To be completed by clinician, even if you’re not Anesthesia personnel Risks/Benefits/Alternatives for Sedation * Required discussion with patient should be documented either on outpatient forms, or in procedure note Risks/Benefits/Alternatives for Procedure * As above, with the addition of signature on procedural consent Sedation Plan: * The level of sedation that was presented to, and accepted by the patient. This must be documented before initiation of the procedure.
26 Prevent wrong site / wrong patient / wrong limb / wrong equipment Site Verification / Marking “YES” on the procedure siteMust be completed before the procedure startsIs the responsibility of the person performing the procedure (clinician)Should be a process which includes patient input / verification / understandingTIME OUT!To be completed immediately before the first dose of sedation / start of the procedure.Is the responsibility of the clinician, although may be documented by the assistantShould be a group interaction (clinician, assistant, others present in the room)Includes four questions: Is this the Correct Patient? Is this the Correct Procedure? Is this the Correct Site?4. Is this the Correct Equipment?
27 Intra-procedure Monitoring requirements Intra-procedure Monitoring requirements * BP, Pulse, Respiratory Rate, SpO2 required immediately before the procedure / first dose of sedation, monitored frequently and documented every 10 minutes throughout the procedure and recovery period. * Mechanical noninvasive blood pressure is preferred, however may use manual (cuff) method. * Continuous Pulse Oximetry * Sedation * Assessed and documented with vital signs * RASS Sedation Scale
28 Richmond Agitation Sedation Scale (RASS) ScoreTerm (not included on documentation forms)Description+4CombativeOvertly combative, violent, immediate danger to staff+3Very agitatedPulls or removes tube(s) or catheter(s), aggressive+2AgitatedFrequent, non-purposeful movement. Fights ventilator+1RestlessAnxious, but movements not aggressive, vigorousAlert and Calm-1DrowsyNot fully alert, but has sustained awakening(Eye-opening/eye-contact) to voice, ≥ 10 seconds-2Light sedationBriefly awakens with eye-contact to voice, <10 seconds-3Moderate sedationMovement or eye-opening to voice, (but no eye contact)-4Deep sedationNo response to voice, but movement or eye opening to physical stimulation-5UnarousableNo response to voice or physical stimulation
29 Intra-procedure Monitoring requirements EKG monitor is applied * Assistants may not be able to perform rhythm interpretation * Is used by the assistant as a tool to identify when more in depth patient assessment is required 1). For example: heart rate drops, assistant may stimulate patient, check BP, or other 2). Another example: heart rate accelerates, assistant may ask patient about comfort level. * Assistants should notify the clinician for any noticeable changes in rhythm, rate, or other concerns noted on monitor for further medicaldirection.* Capnography? * Although not essential this indicates if patient is ventilating adequately. * This will indicate hypoventilation before pulse oximetry. * Currently available to intubated patients only
30 Question 5A 55-year-old woman has a history of adult onset diabetes mellitus. She also has a history of hypertension. Both diseases are controlled by diet alone. This patient is an ASA PS classification of: A. ASA I B. ASA II C. ASA III D. ASA IV E. ASA VAnswer: B
31 Question 6A 71-year-old woman has a history of diabetes and CHF. She is on multiple medications from her physician including nitropaste, atenolol, lasix, and micronase. She lives a very sedentary life. She presents for an EGD for a work-up of her “guiaiac positive stools. On physical exam you hear rales ¼ of the way up on both lung fields. This patient is an ASA PS classification of: A. ASA I B. ASA II C. ASA III D. ASA IV E. ASA VAnswer: D
32 A 55-year-old man is to have a closed reduction of a fractured wrist A 55-year-old man is to have a closed reduction of a fractured wrist. He has a history of ASCVD and had a MI a few years ago. He underwent a carotid endarterectomy last year. He reports that he does get a little tired after walking one block and has to rest after 1 flight of stairs. This patient is an ASA PS classification of: A. ASA I E B. ASA II C. ASA III E D. ASA IV E. ASA V EQuestion 7Answer: C
33 Required monitoring parameters during the procedure include:. A Required monitoring parameters during the procedure include: A. Heart rate, blood pressure, and oxygen saturation B. Heart rate, rhythm interpretation, blood pressure, respirations, oxygen saturation and level of sedation. C. Heart rate, rhythm interpretation, blood pressure, oxygen saturation, capnography and respirations D. Heart rate, blood pressure, respirations, oxygen saturation and level of sedationQuestion 8Answer: D
34 Informed consent needs to be obtained before conscious sedation is administered. Which of the following need not be included in Mr. Brown’s informed consent? A. Medications planned for Moderate Sedation B. Benefits of Moderate Sedation C. Alternatives to Moderate Sedation D. Risks of Moderate SedationQuestion 9Answer: A
35 The clinician is responsible for:. A. Sedation plan. B The clinician is responsible for: A. Sedation plan B. Initiating the “Time Out” C. Completing the history and physical D. All of the aboveQuestion 10Answer: D
36 Which of the following is required for all outpatients prior to the procedure? A. Consent for sedation B. Airway assessment C. Presence of responsible adult D. All of the aboveQuestion 11Answer: D
37 Emergency equipment. Oxygen with nasal cannula / mask Emergency equipment * Oxygen with nasal cannula / mask * Ambu Bag with mask * Suction * Crash Cart * Airway box * Reversal Agents Complications * Usually related to medications / patient response * Respiratory Depression - Patient stimulation may be all that’s needed - Consider use of above emergency equipment * Aspiration - Suction - May be silent. Watch skin color and SpO2 * Hemodynamic instability - Consider fluid bolus * For any complication, consider ACLS guidelines / calling a code (2-4700)
38 If respiratory depression and/or hemodynamic instability occurs, consider use of reversal agents.
39 Assistant Responsibilities Patient assessment and appropriate documentation throughout the procedureReassure patient and monitor patient awareness.Provide comfort measures as neededNotify clinician of changes / concerns.Documentation of required parameters.The Assistant is not to leave patient bedside for any reason during the procedure (although may assist the clinician with short, interruptible tasks) The assistant must be able to drop those tasks if the patient needs attention)
40 Choosing appropriate medications Agents should be chosen based on the desired pharmacological response. Depending on the particular agent one, two or all three of these below effects can be achieved: * Anxiolysis * Analgesia * Amnesia Adverse effects - The potential side effects of any medication in a particular patient must by considered. Many sedative agents can produce cardiac or respiratory depression.
41 Pharmacokinetic Considerations - When selecting a sedative, the following pharmacokinetic parameters should be considered to optimize response in a given situation. * Onset and Duration * Elimination Route * Accumulation * Drug interactions / potentiations * Cross-Tolerance (e.g. patients with prior opiate use may require higher doses of opiates; those with prior ethanol exposure may require larger doses or benzodiazepines, etc.)
42 During the procedure Mr During the procedure Mr.... Green’s vital signs should be documented at least: A. Every 5 minutes B. Every 10 minutes C. Every 15 minutes D. Beginning and end of the procedureQuestion 12Answer: B
43 The assistant’s responsibilities DO NOT include:. A The assistant’s responsibilities DO NOT include: A. Documentation of vital signs B. Patient comfort C. Leaving the room to get supplies D. Assisting with short interruptible tasks during the procedure.Question 13Answer: C
44 Question 14Jane Smith is a 79-year-old female otherwise healthy female who is to have a closed reduction of a right colles fracture under moderate Sedation. Pre-procedure assessment includes BP 142/74, P82, R18, T37.4, Sat 96% room air. Immediately after administration of the medications, Mrs. Smith’s BP drops to 108/56 and her heart rate rises to 98. What should be the first intervention you provide? A. Fluid Bolus B. Romazicon 0.4 mg IVP C. Page for Anesthesia D. Cancel the procedure and reevaluate Mrs. SmithAnswer: A
45 Question 15You have planned moderate sedation. You anticipate the patient will achieve a RASS score of: A. -1 B. -2 C. -3 D. -4Answer: C
46 During a painful procedure, you order morphine 4 mg IV During a painful procedure, you order morphine 4 mg IV. Within a few minutes of the morphine administration the patient’s oxygen saturation is 92%. You should immediately: A. Insert an oropharyngeal airway B. Stimulate the patient C. Apply non-rebreather mask at 12 L/min D. Give a fluid bolusQuestion 16Answer: B
47 Post-procedure Requirements Procedural orders Post-procedure Requirements Procedural orders * Given orally throughout procedure * Written orders required * If assistant is utilizing handwritten documentation, sign, time and date the bottom of monitoring form * If assistant is utilizing computer documentation, write orders for medications etc. in patient chart when writing post-procedure orders and notes. Monitoring requirements * BP / P / RR / SpO2 documented every 10 minutes * Aldrete Score completed with each vital sign documentation
48 Baseline must be done before sedation initiated Baseline must be done before sedation initiated. This is what post-procedure Aldretes are compared to.Post Procedure is done at the end of the procedure, then every 10 minutes until patient meets recovery criteria. A minimum of 3 aldrete scores must be completed before the patient can be identified as “recovered” When recovery criteria are met, the last (frequently the third) Aldrete can be the D/C score.
49 Recovery criteria * A minimum of two consecutive Aldrete scores are baseline minus one with stable vital signs * The patient’s room air oxygen saturation must be back to baseline * Sufficient time (i.e., a minimum of 1 hour) should have elapsed after the last administration of reversal agents (naloxone, flumazenil) to ensure that the patient does not become resedated after reversal effects have abated. * Patients who will be discharged to home and receive IV medications for relief of pain, nausea, vomiting etc. must be observed no less than two consecutive Aldrete / vital sign assessments following administration of such medication
50 Discharge criteria * Vital signs stable (Vital signs include BP, HR, R,& O2 Sat. The VS are determined to be stable if they are consistent with the patient’s age and with the patient’s pre-operative VS) * Swallow, cough present (patient demonstrates ability to swallow fluids and is able to cough * Able to ambulate (patient demonstrates ability to ambulate at pre- procedure level) * Nausea, vomiting, dizziness is minimal * Absence of respiratory distress (patient’s respiratory effort consistent with pre-procedure status) * State of consciousness (patient is alert, oriented to time, place and person consistent with pre-procedure level of consciousness). * Level of comfort (Pain controlled as per BJH pain policy) * Post-procedure (oral and written) discharge instructions are given to the patient and/or significant other regarding the following: purpose and expected effects of sedation, patient’s care, emergency phone number, medications, dietary or activity restrictions, and necessary precautions (e.g., no driving for 24 hours, avoid alcohol and use of power tools, etc.).
51 Question 17After the procedure is completed, your patient’s saturation drops , and Romazicon is given. She is able to support her own airway and her saturations return to normal. The minimal time she needs to be monitored after the romazicon is given before returning her to the nursing unit is: A. 30 minutes B. 1 hour C. 2 hours D. No more monitoring is necessary, the benzodiazepine is reversed.Answer: B
52 After the procedure, your patient states she’s ready to go home After the procedure, your patient states she’s ready to go home. Which of the following would indicate that she would need to stay a little longer? A. Dizziness when first sitting up. B. Systolic BP for the past hour C. Wrist pain, reported 3/10 D. Aldrete score 2 below pre-procedure score. .Question 18Answer: D
53 Question 19Mr. Brown’s mother has not arrived to driver her son home yet. What should the nurse do? A. Send Mr. Brown home in a cab B. Wait another 30 minutes then allow Mr. Brown to take a bus home. C. Allow Mr. Brown to drive home D. Release Mr. Brown only after a responsible individual is present to driveAnswer: D
54 Which of the following information should be included in the discharge instructions when a patient is discharged within 24 hours of receiving procedural sedation? A. Return to your normal activities B. Avoid alcoholic beverages for the next 2 hours C. Do not drive for 24 hours. D. Clear liquid diet for 24 hours.Question 20Answer: C
56 Case #1A 76 year old male with a significant history of COPD, hypertension, diabetes mellitus type 2, chronic renal insufficiency and alcohol-induced liver failure presents for X procedure. The decision is made to sedate the patient with midazolam. An initial bolus dose of 5mg IV push is given and 10 minutes later, the patient remains at his baseline level of consciousness.
57 Pharmacokinetics Onset time (Single bolus dose) DrugOnset Time (minutes)Diazepam1-2Midazolam3-5Lorazepam10-20FentanylMeperidineMorphine5-10
58 What is the usual Midazolam onset time and what is the Question 21What is the usual Midazolam onset time and what is thetime interval that should elapse before a seconddose should be administered?30 seconds, 5 minutes1 minute, 1 minute3-5 minutes, 5 minutes10 minutes, 20 minutesAnswer: C
59 Case #2A 44-year-old male with a significant history of HIV, Chronic renal insufficiency, and diabetes mellitus type 2 presents for X procedure. His current medicationRegimen that includes ritonavir, lamuvidine, zidovudine, pravastatin, and metformin. The patient is sedated with midazolam without apparent complication. A 2 mg IV bolus x 1 is given with an observed Ramsey score of 3 within 5 minutes. The level of sedation is maintained throughout the procedure that is performed without complication. 45 minutes into recovery (150 minutes from last drug dose) the patient is observed to have difficulty walking without assistance.
62 Drug Interactions CYP3A4 Inhibitors Drug affected azole antifungals diltiazemverapamilprotease inhibitorsmacrolidesnefazadonequinupristin-dalfopristinDrug affectedmidazolam
63 What is the expected duration of effect of a Question 22What is the expected duration of effect of asingle bolus of midazolam?20 minutes1 to 2 hours4 hours6 hoursAnswer: B
64 What is the explanation for the prolonged effect? Question 23What is the explanation for the prolongedeffect?Drug-drug interactionChronic renal insufficiencyToo high of doseNone of the aboveAnswer: A
65 Case #3A 28-year-old female with a significant medical history of bilateral lung transplant secondary to cystic fibrosis presents for X procedure. The patient is ordered to receive meperidine 75mg IV x 1, and midazolam 1 mg x 1. When obtaining the pre-procedure history and physical the patient reports she is allergic to meperidine. She received this drug during a previous procedure and was observed to have visual hallucinations.
68 What alternative opioid agent should be Question 24What alternative opioid agent should beconsidered for moderate sedation?FentanylMorphineHydromorphoneB or CAnswer: D
69 Case #4A 56-year-old female undergoing X procedure is complaining of pain. 25 mcg of fentanyl is given in addition to the already administered 2 mg of midazolam. 10 minutes after the dose of fentanyl the patient is still complaining of pain. Another 25 mcg of fentanyl is given, followed by another 25 mcg 5 minutes later (total dose = 75 mcg in 25 minutes). Shortly after the third dose of fentanyl, the patients breathing is observed to be extremely labored and the pulse oximeter reveals an SaO2 of 89%. The patient is placed on 4L/min O2 by nasal cannula with no improvement in SaO2. The decision is made to administer naloxone. 0.4 mg IV x 1. Within minutes the patient recovers respiratory rate and function.
70 Naloxone (Narcan®) Opioid antagonist Dosing: 0.4–2 mg q 2-3 min, up to 10 mgOnset time: 1-2 minDuration of effect: minAdverse effects: precipitate withdrawal, pulmonary edema
71 Flumazenil (Romazicon®) benzodiazepine antagonistDosing: 0.2 mg q 1 min, up to 1 mgOnset time: 1-2 minDuration of effect: minAdverse effects: seizuresReversing BZD-induced hypoventilation has not been established
72 What is the duration of effect of naloxone Question 25What is the duration of effect of naloxoneand what is the minimum amount of timeafter the dose that the patient should bemonitored?30 min-1 hour, 30 minutes30 min- 1 hour, 1 hour1-2 hours, 1 hour1-2 hours, 2 hoursAnswer: B
73 Case #6A 65 year old female presents to the emergency department with a separated shoulder after a fall in her bathroom. She rates her pain as 9/10. Meperidine 75 mg IV q 30 minutes is ordered prior to the moderate sedation procedure to correct the separation. What important history should be obtained prior to meperidine administration?
74 Meperidine (Demerol®) Contraindicated in patients on MAOIs in previous 14 daysPhenelzine (Nardil®)Tranylcypromine (Parnate®)Effects of meperidine/MAOI combinationRespiratory depressionHypotensionComaOther drugs w/ MAOI properties
75 BJH IV Medication Guidelines Drugs with Level 1 MD Coverage Level 1 Coverage: RN may initiate drug therapy with a physician order, provided a physician is available in person to the patient care area within 5 minutes of being contacted.FentanylMidazolam (Versed®)Naloxone (Narcan®)Flumazenil (Romazicon®)
76 What important history should be obtained Question 26What important history should be obtainedprior to meperidine administration?Allergy historySeizure historyMedication historyAll of the aboveAnswer: D
77 What is the usual fentanyl onset time and what is the Question 27What is the usual fentanyl onset time and what is thetime interval that should elapse before a seconddose should be administered?30 seconds, 1 minute1-2 minutes, 2 minutes8-10 minutes, 10 minutes15 minutes, 15 minutesAnswer: B
78 Please note:BJH residents must have an attending in the room to provide procedural sedation.If unsure of drug dosage, please look them up.Please be familiar with the BJH IV Medication Policy, and ask staff nurses if specific medications are allowed to be given in that area.Thank you.
79 ReferencesASA (2002) Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists. Anesthesiology. 96:Lin, DM & Wightman, MA. (2005). Sedation, Anesthesia, and the JCAHO (3rd ed.). HCPro Inc. Marblehead, MA.Sedation by Non-Anesthesia Personnel for Procedures. (2007) BJH Policy/Procedure/GuidelineUniversal Protocol for Preventing Wrong Site, Wrong Procedure and Wrong Person Surgery. (2007) BJH Policy/ProcedureSessler CN, Gosnell M, Grap MJ, Brophy GT, O’Neal PV, Keane KA et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care patients. Am J Respir Crit Care Med 2002; 166:Ely EW, Truman B, Shintani A, Thomason JWW, Wheeler AP, Gordon S et al. Monitoring sedation status over time in ICU patients: the reliability and validity of the Richmond Agitation Sedation Scale (RASS). JAMA 2003; 289: