Presentation on theme: "Emcure’s Initiatives in Anemia Management"— Presentation transcript:
1Emcure’s Initiatives in Anemia Management Dr. P. Bhandari, M.D.
2We bring difference in lives EmcureResearch driven pharmaceutical companyResponsible corporate citizengiving back to society from which it profitsTherapeutic areasAnemiaAIDSCardiologyNephrologyOncologyGynecologyDiabetesNeurologyOrthopedicsGastroenterologyWe bring difference in lives
3Anemia – a global problem According to a survey conducted by NFHS, the prevalence of anaemia in young girls aged between years is 56% with higher rates in rural than in urban India.
4Anemia affects all Mother Child Pre-term delivery Fetal and maternal mortalityLow birth weigh babyChildImpaired mental functionIncreased infectionsFrequent diarrhea
5Anemia – signs/symptoms Fatigue (very common)Weakness (very common)DizzinessShortness of breathIrritabilityLack of concentrationPale skin and tongueBrittle nailsLow hemoglobinIron deficiency anaemia with depapillated tongue, depigmentation of the upper lip and epithelial erosion of the lower lip
6Emcure in Anaemia management Innovative oral iron products:Ferrous ascorbate tablets, suspension, etc.State of the art parenteral iron products:Iron sucrose injectionFerric carboxymaltose injectionBiotechnology products:Erythropoietin
7Ferrous Ascorbate Leaders in the ferrous ascorbate market Offering own R&D ferrous ascorbateGranted Indian PatentThe best oral iron so far:Maximum bioavailability of up to 43%Excellent tolerabilityPrevents inhibitory action of dietary phytates etcProven safety and efficacyDose: 100 mg elemental iron daily for adults
8Why Ferrous Ascorbate?InhibitorsFacilitatorsThe absorption of iron from ordinary iron supplements is approximately 10% or lessThis is due to presence of inhibitory ligands like phytates, tannins, phosphates etc in foodThe presence of ascorbate facilitates absorption by preventing the action of these inhibitory ligandsThis increase absorption of iron from ferrous ascorbate up to 43%
9When oral iron may not be sufficient? In severe anemia that will require very long time to correctVery low iron stores that need quick replenishmentIn renal failure patients who do not respond to oral ironIn menorrhagia-associated severe iron-deficiency anemiaIn anemia associated with cancer Parenteral (IV) iron
10Iron Sucrose Injection The dominant IV iron for anaemia managementDoes not have risk of dextran-induced hypersensitivityUsed by both nephrologists and obstetriciansDose: 100 mg by slow IV bolus x max thrice weekly, or mg IV infusion x max thrice weekly, to replenish cumulative deficit
11Ferric Carboxymaltose Injection The latest IV ironIntroduced first in India by EmcureOffers feasibility of total dose infusion of 1g in 15 minNo dextran-type hypersensitivitySafe & effective in different indications
12ErythropoietinManufactured in Gennova Biopharmaceuticals facility of EmcureMatching European Pharmacopoeia standardsUsed by nephrologists in renal anemiaUsed by obstetricians in EPO-deficient IDA in pregnancy