Presentation on theme: "HAART Highly Active Antiretroviral Therapy"— Presentation transcript:
1 HAART Highly Active Antiretroviral Therapy Randi PuffenbergerShey VeditzGeorge ParishAmy KeisterMatt Lake
2 What is HAART? Triple Therapy Two nucleoside analogsOne protease inhibitorMulti drug regimens useful because many times one drug fails to block viral replication
3 Drawbacks of HAARTRequires at least 8-24 pills a day, with specific dose requirements for eachCan cost $10,000 -$12,000 per yearMemory t-cells all but disappear causing immune system to ‘forget’ how to handle the virusSide effects include: rash, nausea, diarrhea, anemia, neuropathy, hepatitis, diabetes, and headache
4 Treatment Strategy Most appropriate for: People in acute stage of diseaseRare that disease is caught at this stagePeople who already have symptoms or low CD4 t-cell countSymptom less patients with relatively low CD4 t-cell count
5 How HAART Treatment Works Prevents enzyme function by binding to active site of protease enzymePrevents virus replicationUse multiple drugs to counter mutations that cause drug resistance
6 ConclusionPatients using HAART do not develop resistance and with hope can continue on it indefinitelyClinical studies show HAART to be the most effective treatment method for maximum viral suppression
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