Presentation on theme: "The ideal binder for MYCOTOXIN"— Presentation transcript:
1 The ideal binder for MYCOTOXIN SintocheckThe ideal binder for MYCOTOXIN
2 During the time between harvesting and drying , and in storage DEFINITIONMycotoxins are metabolites of molds growing on feedstuffs (Aspergillus, Fusarium, Penicillum).They are spread everywhere and are able to bring about poisoning in the animals that assume contaminated feedMany mycotoxins can contaminate crops before harvest under certain circumstances of humidity and temperature . FIELD MYCOTOXINSDuring the time between harvesting and drying , and in storage STOCK MYCOTOXINS
4 TOXIC EFFECT OF THE MYCOTOXINS Common is the presence of various mycotoxins, even though presentin small amounts,they add their effects,determining a synergistic effect..…. are more dangerous at low levels of different mycotoxins than high levels of single mycotoxinMycotoxins are resistant to all technological treatments.
5 MYCOTOXIN LEGISLATION Directive 2002/32/EC on undesirable substances in animal feed (2006/02/24)0,020,0050,01All feed materialsComplete feedingstuffs for cattle,sheep and goats with the exception of:-complete feedingstuffs for dairy animals-complete feedingstuffs for calves and lambsComplete feedingstuffs for pigs and poultry (except young animals)Other complete feedingstuffsComplementary feedingstuffs for cattle, sheep and goats (except complementary feedingstuffs for dairyanimals, calves and lambs)Complementary feedingstuffs for pigs and poultry (except young animals)Other complementary feedingstuffsAFLATOXIN B1Maximum content in ppm relativeto a feedingstuff with a moisture content of 12 %Products intended for animal feedUndesirable substance(with the new normative may not be mixed for dilution!!)
6 MYCOTOXIN LEGISLATION COMMISSION RECOMMENDATION of 17 August 20060,250,050,1605102050Feed materials-cereals and cereal productsComplementary and complete feedingstuffs-complementary and complete feedingstuffs for pigs-complementary and complete feedingstuffs for poultry-maize and maize productsComplementary and complete feedingstuffs for::-pigs, horses , rabbits and pet animals-fish-poultry, calves (< 4 months), lambs and kids-adult ruminants (> 4 months) and minkiOCHRATOXIN AMaximum content in ppm relativeto a feedingstuff with a moisture content of 12 %Products intended for animal feedUndesirable substanceFUMONISINEB1 + B2FUMONISINB1+B2
7 MYCOTOXIN LEGISLATION COMMISSION RECOMMENDATION of 17 August 200681250,9230,10,250,5Feed materials-cereals and cereal products with the exception of maize by-products- maize by-productsComplementary and complete feedingstuffs with the exception of:-complementary and complete feedingstuffs for pigs-complementary and complete feedingstuffs for calves (< 4 months), lambsand, kidsComplementary and complete feedingstuffs-complementary and complete feedingstuffs for piglets and gilts (young sows)-complementary and complete feedingstuffs for sows and fattening pigs-complementary and complete feedingstuffs for calves, dairy cattle, sheep and goatsDEOXYNIVALENOLMaximum content in ppm relativeto a feedingstuff with a moisture content of 12 %Products intended for animal feedUndesirable substanceZEARALENONE
10 EFFECTS ON SWINE 25-100 ppb of Zearalenone 500-1000 ppb of Fumonisina (less fertility)Less heat during 5 days after weaningMore anaoestrusLess pigglets live births more abortion; litters less uniformRectal and uterus prolapsisppb of Fumonisina( reproduction and respiratory problems)Increase incidence of :PRRS, APP; CRVPulmunary oedemaUnexpected deathLess immune activityIncrease of E.Coli in the intestinal tract
11 100-500 ppb Tricoteceni: A: T-2 e DAS; EFFECTS ON SWINEppb Tricoteceni: A: T-2 e DAS;B: DON ( digestion problems )AnorexiaVomiting (12 ppm)ImmunodepressionDelayed growthSkin and mucous necrosisDAS: Deacetoxiscirpenolo; DON: Deossivalenoloppb AFLATOXIN(hepatic problem)AnorexiaUnexpected death (1000 ppb)Hepatic damage (necrosy, icterus, lipidosy, hemorrages)Delayed growthImmunodepression
12 EFFECTS ON POULTRY kidneys mucous membrane Bood- vessels Sistema emopoieticoedorgani linfoidiBood- vesselskidneysReproductive organteratogenicitàarti
14 EFFECTS ON POULTRY Necrosis Immunodepression Less answer to vaccines Increase cost of therapyMore mortalityLess yieldTOXIC LIMITAflatoxin: 1000 pbbT-2, DAS: 2000 ppbDON: 1000 ppmOchratoxin A: 2000 ppbNecrosis
15 EFFECTS ON RUMINANTS Vulvovaginitis Gastro enteritis Prolepsis Embryo mortalityGastro enteritisIntestinal haemorrhageImmunodepressionCystic ovarianFeed refusalvomitingMilk contaminationDecline in milk productionIncrease in somatic cells
16 EFFECTS ON RUMINANTS Legislative decree n° 149 of 10 May 2004 ZEARALENONE/DONCistic ovarianMiscarriagesMore anaoestrusLess heatTRICOTECENI AND OTHER MYCOTOXINImmunodepressionLess ingestionDecline in milk productionAFLATOXIN B1 AND M1:they are a problem for the health of the consumerLegislative decree n° 149 of 10 May 2004
17 POSSIBLE STRATEGIES IN ORDER TO PREVENT AND TO MANAGE THE MYCOTOXIN PROBLEMS 1 Establish an adequate quality control of feedstuffs 2 Use of mould inhibitor during storage 3 Use mycotoxins binder
18 They do not have effect on the mycotoxins produced on the field ANTIMOULD ADDITIVESThey do not have to be considered the exclusive method of controlCombinations of organic acids (propyonic, sorbic, benzoic and acetic) or salts of organic acids (calcium propionate and potasium sorbate)They must be distributed uniform on all the feedBUT ABOVE ALLThey do not have effect on the mycotoxins produced on the field
19 ADDITIVES ADSORBENT MYCOTOXINS SintocheckNatural Mycotoxin BinderComposition: Hydrated Sodium Calcium Aluminosilicate (HSCAS)New concept:BY USING A WELL BALANCED,COMBINATION OF DIFFERENT HSCASTHAT ARE ACTIVED BY A HEAT DRYING PROCESS ,WE WELL OBTAIN A SYNERGIC EFFECT,INCREASING THE CAPACITY ANDSPECTRUM OF MYCOTOXIN BINDER.
20 WHY CLAYS ARE DIFFERENT? HOW TO COMPARE THEM? CEC: Cation Exchange Capacity (MEQ)< 19 MEQ is considered a saturation point,which makes the clay have a neutralcharge,it's adsorption capacity is minimal>60 MEQ is considered a high CEC,which can interfere inthe adsorption of nutrients,especially minerals.Sintocheck (mixture of illites and chlorites) MEQ
21 WHY CLAYS ARE DIFFERENT? HOW TO COMPARE THEM? EXPANDABLE: Hight cation exchange,more than 60MEQ. Absorb water. Absorb nutrients. NON EXPANDABLE: Lower than 60 MEQ cation exchange capacity Very small to almost no water absorption Very little to no absorption of nutrients.Sintocheck is not expandableDIPOLAR – POLARDipolar clays have a wide spectrum of adsorption of mycotoxins.Polar clays (such as Bentionites) have a negative charge and can only adsorb mycotoxinswith a strong positive chargeSintocheck is dipolar
22 WHY CLAYS ARE DIFFERENT? HOW TO COMPARE THEM? PORE SIZE AND SURFACE AREABentonite = Hight CEC = Smaller surface area = less binding sitesBentonite = Pore size of 1,5 to 1,8 AIllites and chlorites (silicates) = Smaller CEC = Larger surface activity =more binding sites.Illites and chlorites (silicates) = Larger pore size, in range of 2,5 APARTICLE SIZEThe size of particle is very critical:less than 300 mesh reduces the surface area- the best size is between 300 and 400 mesh-at 400 mesh or higher ,particles are too small and could represent hazardousproblems to workes.Sintocheck has a particle size , which is the best for a superior adsorbent
23 WHY CLAYS ARE DIFFERENT? HOW TO COMPARE THEM? PHThere is an interrelationship between the pH of the clay and where the binding is performed in the GI tract of the animal.Clays with an acid pH tend to work better in the large intestine.Clays with an alkaline pH perform their binding in the lower intestine.Many scientists and nutritionists believe it is better for a clay to work in the lower intestine.SINTOCHECK HAS A PH OF 7,8 TO 8,THEREFORE IT PERFORMS BINDING IN THE LOWER INTESTINE
24 WHY CLAYS ARE DIFFERENT? HOW TO COMPARE THEM? TEMPERATURE WHICH THE CLAYS ARE SUBMITTED TO DURING PROCESSINGTemperature may have an effect on the cation exchange due to solubility and temperature reationship.Many clays are extracted from the ground ,then ground into finer particles with no heat being applied for drying.Drying clays at normal temperatures of 200 to 300 F°(95-150°C) can make the clay more active and have a better cation interchange.If excess temperature is used in drying,for example,900 F°(480°C),the components crystallize or fragment,rendering the clay ineffective as a single component or as a unit for mycotoxin adsorbtion.SINTOCHECK is dried at temperature of 100 and 105 °Cwhich is the range of temperature which can make the clay more active andhave better cationic exchange,therefore a must better binder.
25 SINTOCHECK It is different because… Hydrated Sodium Calcium Aluminosilicate (HSCAS) naturalBig binding capacity and large spectrum of mycotoxin binderIrriversible bond with mycotoxinsThe small particle size allows an optimal homogenization with the other feed ingredients contributing to solve also the problems of fluidity and caking.
26 BINDING CAPACITY OF SINTOCHECK SINTOCHECK is tested using 5ppm mycotoxin at inclusion level of 2,5 Kg/TON99% Aflatoxin M197% Citrinin95% Aflatoxin B194% T284% Vomitoxin84% Don72% Fumonisin B172% Ochratoxin A43% ZearalenoneM1 CIT B1 T2 VOM DO F.B1 0CR ZEA
27 A CONCEPT OF HOW SINTOCHECK WORKS MAGNETIC ATTRACTION: A difference in electrical charge between Sintocheck and mycotoxins.Sintocheck works like a magnetmycotoxin2. PARTICLE SIZE: The particle size of Sintocheck provides a larger surface area that maximizes the binding of mycotoxins.SintocheckOTHER PRODUCTMYCOTOXINMYCOTOXIN
28 A CONCEPT OF HOW SINTOCHECK WORKS 3.PORE VOLUME: SINTOCHECKhas an ideal pore volume to bind a large percentage of mycotoxins. Using SINTOCHECK is like having a number of magnets in one.SINTOCHECK with bound mycotoxinsMICOTOXINMICRO-BONDMICOTOXINMICOTOXINBINDING MYCOTOXINS CAUSES A LARGER COMBINED PARTICLE OR MOLECULAR SIZE WHICH IS NOT ADSORBED BY THE DIGESTIVE TRACT IT IS PASSED IN THE FECES,CAUSING NO HARM TO THE ANIMAL'S PERFORMANCE.
29 SINTOCHECK Dosage: 2,5 Kg/ton SINTOCHECK does not affect,nor is affected by other ingredients such as:antibiotics/medicinalriboflavinvitamin A- zinc - manganesephosphorusDosage: 2,5 Kg/ton
30 SINTOCHECK Pigs, poultry,fishes, horses, pets Ruminants 1,0-1,5 Kg Prevention of risk2,0-2,5 KgPresence of mycotoxin1,5-2,0 KgSospect of mycotoxinPer ton of feedPigs, poultry,fishes, horses, pets50 g/head /dabeef cattle60 g/head /daydairy cowsRuminants