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Biography Mr. Sarfraz Ahmad is working at Aberdeen Royal Infirmary Hospital, NHS Grampian, Aberdeen, UK. He did his medical graduation (MBBS) from Nishtar Medical College Multan, Pakistan. For his work on ‘DNA vaccination for Prostate cancer’ he was awarded with PhD from National University of Ireland in 2010. He holds a prestigious clinical fellowship from Focused Ultrasound Surgery Foundation, Virgina USA. Additionally, he also had a Membership (MRCS) & a Fellowship of Royal College of Surgeons of Edinburgh in Urology (FRCS Urol). His main clinical inters include, Uro-oncology, minimal invasive/ Robotic Urology, investigating new methods for Urological cancer detection, Focused Ultrasound and cancer immunotherapy.
Biography He has presented his research work in numerous scientific /clinical meetings around the world. His published work is highly appreciation from experts peers and it is cited extensively in international literature. He received prestigious awards from the European Association of Urology in 2010 and from Irish Journal of Medical Science in 2009. Additionally, he received “Young Investigator award” from Focused Ultrasound Surgery Foundation, Washington, USA.
Main Research Interests Development of DNA vaccination for Prostate cancer Quantitative Shear Wave Elastography for prostate cancer Bladder cancer Diagnosis using Raman Spectroscopy Focused Ultrasound for bony metastases Photodynamic Diagnosis of upper and lower urinary tract transitional cell carcinoma (TCC)
Scientific Awards 2009 - Irish journal of medical Science (IJMS) Doctors Award for best paper published from Ireland in all surgical specialities (between 2007 - 2009)
Scientific Awards 2010 - European Association of Urology award for best paper published on fundamental research in Urological literature in 2009
Scientific Awards 2012 - Young Investigator Travel Award, 3 rd International Symposium on Focused Ultrasound, Washington, USA The prestigious award was given for following work; “Localisation of Prostate Cancer Foci with Transrectal Quantitative Shear Wave Elastography – A Step Towards Focal Therapy for Prostate Cancer”
Main Publications Significance of MUC1 in bladder cancer, S. Ahmad, TB. Lam, J. N' Dow, BJUI – Feb 2014 PMID: 24593053 Editorial – Fusion of MRI and TRUS images for targeted biopsy of prostate, S. Ahmad, J Med Diagn Meth Feb 2014 Training model for transurethral resection of prostate using human cadavers embalmed by Thiel's method, S. Ahmad, D. Byrne, G. Nabi, Journal of Endourology, Part B: Videourology, Sept 2013 Transrectal Quantitative Shear Wave Elastography in the Detection and Characterisation of Prostate Cancer, S. Ahmad, R. Cao, T. Varghese, L. Bidaut, G. Nabi, Surgical Endoscopy, Sept 2013, PMID: 23525883 Mitomycin C instillation following ureterorenoscopic laser ablation of upper urinary tract carcinoma, O. Aboumarzouk, B. Somani, S. Ahmad, G. Nabi, N. Townell, S. G. Kata, Urology Annalas, July 2013, PMID 24049383 DNA vaccination for Prostate cancer, from preclinical to clinical trials – where we stand? S. Ahmad, P. Sweeney, G. C. O’Sullivan, M. Tangney, Genetic Vaccines and Therapy Oct. 2012, PMID: 23046944
Main Publications Response of Thiel-embalmed Human Liver and Kidney to MR- guided Focused Ultrasound Surgery, I. Karakitsios, T. Saliev, H. McLeod, S. Ahmad, R. Eisma, A. Melzer, Biomed Tech (Berl), August 2012 –PMID: 22944917 An 11-year of the prevalent uropathogens and the changing pattern of Escherichia coli antibiotic resistance in 38,530 community urinary tract infections, Dublin 1999–2009, Cullen IM, Manecksha RP, McCullagh E, Ahmad S, Flynn, R, McDermott TED, Murphy P, Grainger R, Fennell JP, Thornhill JA, Ir J Med Sci, June 2012 – PMID: 22669684 Oral 5 - aminolevulinic acid in simultaneous photodynamic diagnosis of upper and lower urinary tract transitional cell carcinoma – a prospective audit, S. Ahmad, O. Aboumarzouk, B. Somani, G. Nabi, S. G. Kata, BJUI, March 2012 – PMID 22758907 Estimation of clincally significant prostate volumes by digital rectal examination - a comparative prospective study, S. Ahmad, R.P. Manecksha, I.M. Cullen, T.E.D. McDermott, R. Flynn, R. Grainger, J.A. Thornhill, Can J Urol, 2011 Dec: PMID: 22166330 A minimal invasive temporary cavernoso-saphenous shunt in the management of priapism, M. Edward, O. Aboumarzouk, S. Ahmad, G. Nabi, Minimally invasive Therapy & Allied Tech 2011 Dec. PMID: 22142185
Prospective randomized controlled trial comparing trigonal versus trigone-sparing intradetrusor injection of botulinum toxin A for refractory idiopathic detrusor overactivity Manecksha, R.P., Cullen, I.M., Ahmad, S., McNeill, G.J., McDermott, T.E.D., Flynn, R.J., Grainger, R., Thornhill, J.A., Eur Urol, 2011 Nov 7. PMID: 22078337 Survival after incidental prostate cancer diagnosis at transurethral resection of prostate – 10 year outcomes, S. Ahmad, F. O’Kelly, R.P. Manecksha, I.M. Cullen, R. Flynn, T.E.D. McDermott, R. Grainger, J. A. Thornhill, Ir J Med Sci, 2011 Sept. PMID: 21910023 The changing pattern of antimicrobial resistance within 42033 Escherichia coli isolates from nosocomial, community and urology patient-specific urinary tract Infections, Dublin, 199 -2009, Cullen IM, Manecksha RP, McCullagh E, Ahmad S, O'Kelly F, Flynn RJ, McDermott T, Murphy P, Grainger R, Fennell JP, Thornhill JA, BJU Int. 2011 Aug 24. PMID: 21883861 Induction of effective anti-tumour responses following mucosal bacterial vector mediated DNA vaccination with an endogenous prostate cancer specific antigen, S. Ahmad, G. Casey, M. Cronin, S. Rajendran, P. Sweeney, M. Tangney, G. C. O'Sullivan, J Urol. 2011 Aug; 186(2): 687-93 PMID: 21683415 Case report of a symptomatic giant renal oncocytoma, S. Ahmad, R. Manecksha, B. D. Hayes, R. Grainger, Int J Surg Case Rep 2011 March, PMID 22096690 Main Publications
Gene therapy for prostate cancer, M. Tangney, S. Ahmad, S. A. Collins, G. C. O’Sullivan, Postgrad Med. 2010 May; 122(3):166-80, PMID: 20463426 Optimise electroporation mediated DNA vaccination for prostate cancer, S. Ahmad, G. Casey, P. Sweeney, M. Tangney, G. C. O'Sullivan, Genetic Vaccines and Therapy 8:1 2010 Feb, PMID: 20181099 VHL genetic alteration in CCRC does not determine deregulation of HIF, CAIX, hnRNPA2/B1 and osteopontin, Nyhan MJ, EL Mashad SM, O’Donovan TB, Ahmad S, Collins C, Sweeney P, Rogers E, O'Sullivan GC, McKenna SL Anal Cell Pathol 2010 Jan 1; 33 (3):121-32. PMID: 20978319 Prostate stem cell antigen DNA vaccination breaks tolerance to self-antigen and inhibits prostate cancer growth, S. Ahmad, G. Casey, P. Sweeney, M. Tangney, G. C. O'Sullivan Molecular Therapy 17, 1101-1108, 2009 Jun PMID: 19337234 Retroperitoneal paraganglioma, a rare but important diagnosis, S. Ahmad, C. Dewhurst, M. Sheikh, P. Sweeney, Ir J Med Sci 178 (2), 211- 4, 2009 Jun PMID: 18183473
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