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OMICS Group Contact us at: OMICS Group International through its Open Access Initiative is committed to make genuine and.

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Presentation on theme: "OMICS Group Contact us at: OMICS Group International through its Open Access Initiative is committed to make genuine and."— Presentation transcript:

1 OMICS Group Contact us at: OMICS Group International through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community. OMICS Group hosts over 400 leading-edge peer reviewed Open Access Journals and organizes over 300 International Conferences annually all over the world. OMICS Publishing Group journals have over 3 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over eminent personalities that ensure a rapid, quality and quick review process. OMICS Group signed an agreement with more than 1000 International Societies to make healthcare information Open Access.

2 OMICS Group welcomes submissions that are original and technically so as to serve both the developing world and developed countries in the best possible way. OMICS Journals are poised in excellence by publishing high quality research. OMICS Group follows an Editorial Manager® System peer review process and boasts of a strong and active editorial board. Editors and reviewers are experts in their field and provide anonymous, unbiased and detailed reviews of all submissions. The journal gives the options of multiple language translations for all the articles and all archived articles are available in HTML, XML, PDF and audio formats. Also, all the published articles are archived in repositories and indexing services like DOAJ, CAS, Google Scholar, Scientific Commons, Index Copernicus, EBSCO, HINARI and GALE. For more details please visit our website: OMICS Journals are welcoming Submissions

3 Editor Journal of Aging Science

4 Suresh Rattan PhD, DSc Laboratory of Cellular Ageing Department of Molecular Biology and Genetics Aarhus University - DENMARK Suresh Rattan PhD, DSc Laboratory of Cellular Ageing Department of Molecular Biology and Genetics Aarhus University - DENMARK Healthy Ageing, but What is Health and How to Maintain it?

5 Health is a state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity. What is health…?

6 Idealistic definition ABSOLUTE physical and mental independence in ADL. Pragmatic and realistic definition ADEQUATE physical and mental independence in ADL. Health in terms of Activities of Daily Living (ADL)…. Nobody has it….

7 Average lifespan Maximum lifespan Biologically, at what point in lifespan ageing begins? Essential lifespan (ELS)

8 Biologically, ageing happens after essential lifespan (ELS) of the species Psychologically, human ageing “stops” after ELS of about years.

9 Ageing occurs at all levels of biological organisation, but differently…

10 we are not programmed to age and die There are no gerontogenes whose sole function is to cause ageing and eventual death Genes determine essential lifespan of a species (longevity-assurance genes; vitagenes)

11 Not homeostasis, but HOMEODYNAMICS

12 Ageing is the shrinkage of the homeodynamic space

13 Anti-ageing or healthy ageing?

14 Ageing interventions: 1.Wishful thinking and miracles 2.Piecemeal remedies / replacements 3.Replenishments – hormones, anti-oxidants 4.Wholistic interventions.

15 Wholistic interventions for maintaining health

16 Three types of dose response curves… HORMESIS Biphasic dose response U-shaped response Inverted-U shape response Adaptive response Compensatory response HORMESIS Biphasic dose response U-shaped response Inverted-U shape response Adaptive response Compensatory response

17 Challenging of homeodynamics stimulates compensatory, adaptive, and reparative processes. Strengthening the homeodynamics by mild stress-induced HORMESIS

18 Some examples from our labs Repeated mild heat shock slows down ageing, improves angiogenesis, wound healing and healthspan

19 A condition that causes hormesis is: HORMETIN The science of hormesis is HORMETICS A condition that causes hormesis is: HORMETIN The science of hormesis is HORMETICS Physical hormetins exercise, heat, cold, radiation… Psychological hormetins Social and mental engagement, focussed attention (meditation) Nutritional hormetins spices, micronutrients, fasting

20 Hormesis for humans – Health beneficial effects of stress of choice….

21 What we need for maintaining health…. Biological level – food, shelter, biomedical technology Sociological level – identity, contact, communication Psychological level – attitude, ethics, connection

22 Aging Science Related Journals  Anaplastology  Journal of clinical & experimental Dermatology Reasearch  Anaplastology  Journal of clinical & experimental Dermatology Reasearch

23  5th International Conference on Clinical & Experimental Dermatology Aging Science Related Conferences

24 OMICS Group Open Access Membership OMICS publishing Group Open Access Membership enables academic and research institutions, funders and corporations to actively encourage open access in scholarly communication and the dissemination of research published by their authors. For more details and benefits, click on the link below: OMICS publishing Group Open Access Membership enables academic and research institutions, funders and corporations to actively encourage open access in scholarly communication and the dissemination of research published by their authors. For more details and benefits, click on the link below:


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