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Mutant PrP Suppresses Glutamatergic Neurotransmission in Cerebellar Granule Neurons by Impairing Membrane Delivery of VGCC α2δ-1 Subunit Assunta Senatore,

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Presentation on theme: "Mutant PrP Suppresses Glutamatergic Neurotransmission in Cerebellar Granule Neurons by Impairing Membrane Delivery of VGCC α2δ-1 Subunit Assunta Senatore,"— Presentation transcript:

1 Mutant PrP Suppresses Glutamatergic Neurotransmission in Cerebellar Granule Neurons by Impairing Membrane Delivery of VGCC α2δ-1 Subunit Assunta Senatore, Simona Colleoni, Claudia Verderio, Elena Restelli, Raffaella Morini, Steven B. Condliffe, Ilaria Bertani, Susanna Mantovani, Mara Canovi, Edoardo Micotti, Gianluigi Forloni, Annette C. Dolphin, Michela Matteoli, Marco Gobbi, Roberto Chiesa Neuron Volume 74, Issue 2, Pages 300-313 (April 2012) DOI: 10.1016/j.neuron.2012.02.027 Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

7 Figure 6 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

8 Figure 7 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

9 Figure 8 Neuron 2012 74, 300-313DOI: (10.1016/j.neuron.2012.02.027) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions


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