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Copyright © 2015 Cengage Learning® Chapter 13 Autonomic Nervous System Drugs
Copyright © 2015 Cengage Learning® Introduction Autonomic nervous system (ANS) –Automatic, self-governing, or involuntary No conscious control –Divided into sympathetic (alert system) and parasympathetic nervous system (resting and digesting system) Neurotransmitters: chemical substances released at nerve endings within these systems to transmit nerve impulses 2
Copyright © 2015 Cengage Learning® Introduction (cont’d.) Drugs that affect function of the autonomic nervous system –Adrenergics –Adrenergic blockers –Cholinergics –Cholinergic blockers 3
Copyright © 2015 Cengage Learning® Introduction (cont’d.) The following slides discuss various autonomic nervous system drugs –Refer to the chapter for specific actions, uses, side effects, contraindications, cautions, and interactions of each 4
Copyright © 2015 Cengage Learning® Adrenergics Sympathetic nervous system –Emergency system used to mobilize the body for quick response and action –Key words: fright, fight, or flight What are adrenergics? –Drugs that mimic the action of the sympathetic nervous system 5
Copyright © 2015 Cengage Learning® Adrenergic Blockers Drugs that block the action of the sympathetic nervous system –Most commonly used drugs in this category are the alpha- and beta-adrenergic blockers, or alpha-blockers and beta-blockers Alpha-adrenergic blockers are discussed in Chapters 15 and 25 Prototype of the beta-adrenergic blockers is propranolol (Inderal) 6
Copyright © 2015 Cengage Learning® Cholinergics What do parasympathetic nerve fibers do? –Synthesize and liberate acetylcholine as the mediator What are cholinergics? –Drugs that mimic the action of the parasympathetic nervous system 7
Copyright © 2015 Cengage Learning® Cholinergic Blockers What are cholinergic blockers? –Drugs that block the action of the parasympathetic nervous system Also called parasympatholytic –Common use of anticholinergics is scopolamine transdermal patches Treat or prevent sea-sickness by decreasing gastric secretions and motility 8
Copyright © 2015 Cengage Learning® Cholinergic Blockers (cont’d.) Anticholinergics are most commonly used as preoperative medications –Atropine and glycopyrrolate (Robinul) Reduce secretions of the mouth, pharynx, bronchi, and GI tract and reduce gastric activity –Used to prevent cholinergic effects during surgery, such as hypotension or bradycardia and some cardiac arrhythmias associated with general anesthetics or vagal stimulation 9
Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Chapter 13 Autonomic Nervous System Drugs.
Slide 1 Copyright © 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. Chapter 13 Drugs Affecting the Autonomic Nervous System.
Chapter 33 Agents Affecting the Autonomic Nervous System.
Lecture 3 Autonomic Nervous System. Chapter 20 Autonomic Nervous System n n Central Nervous System (CNS) - Brain and spinal cord n n Peripheral Nervous.
Chapter 34 The Autonomic Nervous System. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved Autonomic.
AUTONOMIC NERVOUS SYSTEM LECTURE 6 PHARMACOLOGY. Autonomic Pharmacology Autonomic Nervous System – This system is divided into two separate systems. –
Autonomic Nervous System Sympathetic (Adrenergic) Parasympathetic (Cholinergic) Have a balancing effect.
Autonomic Nervous System. Homeostasis Integration Receptors Effectors Feed-back.
DRUGS AFFECTING THE AUTONOMIC NERVOUS SYSTEM 10/8/2015Winter
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc. Chapter 5 Autonomic Drugs.
Drugs Affecting Peripheral Nervous System #2. Fight or Flight versus the Parasympathetic Pig.
PowerPoint ® Lecture Slides prepared by Leslie Hendon, University of Alabama, Birmingham HUMAN ANATOMY fifth edition MARIEB | MALLATT | WILHELM 15 Copyright.
PHARMACOLOGY REVIEW. What is Pharmacology ? Pharmacology Pharmacokinetics Pharmacodynamics What the body does to drug What the drug does to body Pharmacotherapeutics.
Drugs of the Peripheral Nervous System. The Nervous System Review.
HEART CONTROL DR. HANA OMER. CONTROL OF CARDIAC OUTPUT The control of cardiac output is essential for adjustments of the blood pressure and blood flow.
MCMP 441 DOR 101 Pharmacology Abdelkader Ashour, Ph.D. 3 rd Lecture.
Copyright © 2005 Pearson Education, Inc., publishing as Benjamin Cummings The Autonomic Nervous System and Visceral Sensory Neurons The Autonomic Nervous.
Chapter 14. Nervous System Central Nervous System (CNS) Brain Spinal Cord Peripheral Nervous System (PNS) Motor (efferent) Autonomic (involuntary) Sympathetic.
THE AUTONOMIC NERVOUS SYSTEM Chapter 14. Divisions of the Nervous System.
1 A N S NERVOUS SYSTEM PNS CNS EFFERENT AFFERENT ANS SOMATIC ENTERIC PARASYMPATHETIC SYMPATHETIC.
The Autonomic Nervous System Nervous System Nervous System Central Peripheral Somatic Control out Autonomic Control inside.
Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 14 Muscarinic Agonists and Antagonists.
LECTUR (2) The neurotransmitters & receptors of Autonomic NS.
Lecture The Autonomic Nervous System The Autonomic Reflex: It is a system that designate both Visceral and Somatic neurons that serve as afferent pathways,
Drugs Affecting the Autonomic Nervous System Adrenergic and Cholinergic Agents and Blockers.
Copyright (c) 2004 Elsevier Inc. All rights reserved. Physiology of the Peripheral Nervous System Chapter 13.
Nervous System The ANS and Simple Behaviour Patterns.
Chapter 11 Peripheral Nervous System. Peripheral Nervous SystemOutline Introductory Comments 1. Autonomic Nervous System Parasympathetic versus sympathetic.
Lecture 14 & 15 Dr. Zahoor Ali Shaikh 1. Central Nervous System (CNS) – brain and spinal cord. Peripheral Nervous System (PNS) – afferent and efferent.
THE AUTONOMIC NERVOUS SYSTEM (ANS). What is the autonomic nervous system? The autonomic nervous system (ANS) is the motor division of the peripheral.
Autonomic Nervous System Dr Dileep Verma Associate Professor Deptt of Physiology KGMU.
The digestive tract plays a role of bringing life sustaining elements into the body and taking waste products out of it.
Chapter 14 - The Autonomic Nervous System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction ANS Anatomy Receptors Effects of the ANS.
Chapter 21 Cholinergic-Blocking Drugs Copyright © 2014 by Mosby, an imprint of Elsevier Inc.
The autonomic nervous system Anatomic organization of the nervous system Nervous system Central nervous system Enclosed in bony cavities (skull, vertebral.
Pharmacology PHL 211 Ninth Lecture By Abdelkader Ashour, Ph.D. Phone:
Mosby items and derived items © 2008, 2002 by Mosby, Inc., an affiliate of Elsevier Inc. Chapter 5 The Central and Peripheral Nervous Systems.
AUTONOMIC NERVOUS SYSTEM Mohammed Alzoghaibi, Ph.D
Peripheral Nervous System. Area outside of CNS Consists of: – Nerves – Scattered ganglia.
SAMUEL AGUAZIM (MD) AUTONOMIC NERVOUS SYSTEM PHARMACOLOGY.
CHAPTER 4 Pharmacology. WHAT IS THE DIFFERENCE BETWEEN CNS AND PNS?
Autonomic Nervous System. Fig General functions Control and Adaptation of body systems to internal and/or external changes.
The Autonomic nervous system. Aims: The aim of this session is to provide you with a short talk about the Autonomic Nervous System Objective: By the end.
Cholinergic agonists & Cholinergic antagonists Adrenergic agonists & Adrenergic antagonists.
Notes pg 71 Title: Nervous System How does information get from one place in your body to another?
1 PHL. 313 Dr. Khairy Zoheir. Lab.1 INTRODUCTION TO NS PHARMACOLOGY and DOSE- RESPONSE CURVE.
The Autonomic Nervous System BIO 137 Anatomy & Physiology.
AUTONOMIC NERVOUS SYSTEM The ANS is part of the efferent portion of the peripheral nervous system.
The Structure of the Nervous System. Divisions of the Nervous System.
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