Presentation is loading. Please wait.

Presentation is loading. Please wait.

Antiviral for Influenza. Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada Percent Bowles et al. J Amer Geriatric.

Similar presentations


Presentation on theme: "Antiviral for Influenza. Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada Percent Bowles et al. J Amer Geriatric."— Presentation transcript:

1 Antiviral for Influenza

2 Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada Percent Bowles et al. J Amer Geriatric Society 50: 608, 2002

3 Use of the Selective Oral Neuraminidase Inhibitor Oseltamivir to Prevent Influenza

4 Clade 1 H5N1 viruses: All Resistant Clade 2 H5N1 viruses: Sensitive - in most recent isolates Resistant – in some isolates from Indonesia The incidence of Adamantane and Neuraminidase Inhibitor Resistance among Clade 1 and Clade 2 Clade 1 H5N1 viruses: Sensitive to oseltamivir & Zanamivir Several mutants resistant to oseltamivir Clade 2 H5N1 viruses All sensitive to oseltamivir & Zanamivir Adamantane : Amantadine/Rimantadine NA inhibitor : Oseltamivir/Zanamivir

5 INFLUENZA BERBEDA DENGAN SARS INLUENZA INLUENZA TERMASUK PENYAKIT YANG MEMILIKI PROPORSI PENULARAN INFEKSI SEBELUM MUNCUL SIMTOM ATAU PENULARAN OLEH INFEKSI YANG ASIMTOMATIK TINGGI (40- 50%) TERMASUK PENYAKIT YANG MEMILIKI PROPORSI PENULARAN INFEKSI SEBELUM MUNCUL SIMTOM ATAU PENULARAN OLEH INFEKSI YANG ASIMTOMATIK TINGGI (40- 50%) Reproductive rate (Ro = 3) Reproductive rate (Ro = 3) INFLUENZA TERMASUK INFLUENZA TERMASUK TIDAK AKAN MUDAH DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING TIDAK AKAN MUDAH DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING SARS SARS SARS TIDAK MENULAR PADA MASA INKUBASI SARS TIDAK MENULAR PADA MASA INKUBASI Reproductive rate (Ro=1,7) Reproductive rate (Ro=1,7) TERMASUK PENYAKIT YANG POTENSIAL DAPAT DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING TERMASUK PENYAKIT YANG POTENSIAL DAPAT DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING Factors that make an infectious diseases outbreak controllable. Proc.of Nat. Acad.Sci. 2004,101;


Download ppt "Antiviral for Influenza. Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada Percent Bowles et al. J Amer Geriatric."

Similar presentations


Ads by Google