Presentation on theme: "Remnants of the Tuskegee Syphilis Study Effects on University Freshmen: Yet a Possible Barrier to Research Participation? Crystal B. Spivey, MPH, DrPH."— Presentation transcript:
Remnants of the Tuskegee Syphilis Study Effects on University Freshmen: Yet a Possible Barrier to Research Participation? Crystal B. Spivey, MPH, DrPH March 9, 2004 Supported by: R24MD00151 NCMHD
Co- Authors Tina Simpson, MD 1 Tina Vazin, PhD 2 M. Kim Oh, MD 1 Karyn Gunn, PhD 2 1 University of Alabama at Birmingham, AL 2 AL State University, Montgomery, AL
Introduction African Americans lag behind the overall population on virtually all health status indicators African Americans’ decision to participate in research is a difficult one Tuskegee Syphilis Study (1932-1972)?
Purpose of the Study Identify clinical research interest of young college students Identify perceived barriers to research participation
Methods: Setting Historically Black College University in the Southeastern U.S.
Methods Cross-sectional survey Conducted Fall 2003 (Sept-Oct) Chi-square method of analysis
Survey Instrument Participant Demographics (race, gender, and age) Level of interest in STD/HIV and pregnancy prevention clinical trials Perception of barriers
Study Population Characteristics N = 691 95% African Americans (less than 1% White, 3% more than one race, and 1% did not categorize ) 57% Females 16-24 years of age Mean age 18
Interest in participation in clinical trials Level of Interest
Impact of the Unethical Aspects of the Tuskegee Syphilis Study
Impact of the Tuskegee Syphilis Study P-value =.020 Level of Impact
Gender Differences P-value <.001 Level of Impact
Association between Tuskegee Syphilis Study and other study barriers Lack of Interestp-value <.001 Confidentiality p-value<.001 Mistrust p-value<.001
Conclusions Tuskegee Syphilis Study continues to influence African Americans willingness to participate in clinical research Confidentiality Issues very important Must build a foundation to develop trust