Presentation is loading. Please wait.

Presentation is loading. Please wait.

RESITRA Red de EStudio de la Infección en el TRAsplante Research network for the study of infection in transplantation Dr Jordi Carratala Hospital de Bellvitge.

Similar presentations


Presentation on theme: "RESITRA Red de EStudio de la Infección en el TRAsplante Research network for the study of infection in transplantation Dr Jordi Carratala Hospital de Bellvitge."— Presentation transcript:

1 RESITRA Red de EStudio de la Infección en el TRAsplante Research network for the study of infection in transplantation Dr Jordi Carratala Hospital de Bellvitge. Barcelona

2 DEFINITION AND OBJECTIVES

3 RESITRA Network of specialists in different fields of transplantation medicine, belonging to the main hospitals that perform SOT and BMT in Spain. Sponsored by Spanish Ministry of Health 16 participating centers and 3 reference laboratories Surveillance began September 2003 All transplant recipients were recorded in the database

4 HVH Clinic Bellvitge Sant Pau Tries i Pujol Doce Octubre Ramón y Cajal Gregorio Marañón Puerta de Hierro Princesa JUAN CANALEJO CRUCES LA FE SON DURETA VIRGEN DEL ROCÍO REINA SOFIA 16 centers 50% BMT

5 OBJECTIVES 1. Infection knowledge in the transplant setting 2. Use of new immunological and molecular tools for the diagnosis and treatment of infection in transplant recipients 3. High-level training in biomedical research for physicians, nursing staff and technicians 4. Network for clinical trials 5. Contact with other european groups or networks

6 RESITRA

7 METHODS

8 Tools for developping the network DATABASE BANK Serum Plasma DNA Microorganisms Tissues Levels of Information Basic : Registry Advanced: formulate new hypothesis Dissemination knowledge Interconnection basic research Teaching European groups Clinical trials

9 DATABASE PRETRANSPLANT PERITRANSPLANT FOLLOW -UP to 2 y Bacterial Infection Viral Infection Fungal Infection Other Infection REJECTION Other medical-surgical complications Sample Bank DATABASE

10 INFORMATIC TOOL Web Web

11 INFORMATIC TOOL Applicative

12 HERRAMIENTA INFORMATICA Applicative on-line

13

14 INFORMATIC TOOL Databases Forms

15

16 1-09-03//1-03-05 * 30-04-05//15-01-06

17 1330 979 167 283 944 PANCREAS 53 RESITRA. 1-09-03 // 01-03-05

18 RESULTS

19 RESITRA San-Juan R, Aguado JM, Lumbreras C, Fortun J, Len O, Muñoz P, Montejo M, Moreno A, Cordero E, Blanes M, Ramos A, de la Torre-Cisneros J, Lopez-Medrano F, Carratala J, Moreno E; RESITRA-REIPI Network, Spain. Universal Prophylaxis With Fluconazole for the Prevention of Early Invasive Fungal Infection in Low-Risk Liver Transplant Recipients. Transplantation. 2011 Aug 15;92(3):346-350. Fortun J, Martin-Davila P, Pascual J, Cervera C, Moreno A, Gavalda J, Aguado JM, Pereira P, Gurguí M, Carratala J, Fogueda M, Montejo M, Blasco F, Bou G, Torre-Cisneros J; RESITRA Transplant Network. Immunosuppressive therapy and infection after kidney transplantation. Transpl Infect Dis. 2010 Oct;12(5):397-405. Torre-Cisneros J, Doblas A, Aguado JM, San Juan R, Blanes M, Montejo M, Cervera C, Len O, Carratala J, Cisneros JM, Bou G, Muñoz P, Ramos A, Gurgui M,Borrell N, Fortún J, Moreno A, Gavalda J; Spanish Network for Research in Infectious Diseases. Tuberculosis after solid-organ transplant: incidence, risk factors, and clinical characteristics in the RESITRA (Spanish Network of Infection in Transplantation) cohort. Clin Infect Dis. 2009 Jun 15;48(12):1657-65.

20 RESITRA Len O, Gavaldà J, Blanes M, Montejo M, San Juan R, Moreno A, Carratalà J, de la Torre-Cisneros J, Bou G, Cordero E, Muñoz P, Cuervas-Mons V, Alvarez MT, Borrell N, Fortun J, Pahissa A; Spanish Research Network for the Study of Infection in Transplantation. Donor infection and transmission to the recipient of a solid allograft. Am J Transplant. 2008 Nov;8(11):2420-5. San Juan R, Aguado JM, Lumbreras C, Fortun J, Muñoz P, Gavalda J, Lopez- Medrano F, Montejo M, Bou G, Blanes M, Ramos A, Moreno A, Torre-Cisneros J, Carratalá J; RESITRA Network of the Spanish Study Group of Infection in Transplantation. Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation. Clin Infect Dis. 2008 Oct 1;47(7):875-82.. Ramos A, Asensio A, Muñez E, Torre-Cisneros J, Blanes M, Carratalá J, Segovia J, Munoz P, Cisneros JM, Bou G, Aguado JM, Cervera C, Gurgui MM. Incisional surgical infection in heart transplantation. Transpl Infect Dis. 2008 Jul;10(4):298-302. Ramos A, Asensio A, Muñez E, Torre-Cisneros J, Montejo M, Aguado JM, Cofán F, Carratalá J, Len O, Cisneros JM. Incisional surgical site infection in kidney transplantation. Urology. 2008 Jul;72(1):119-23.

21 RESITRA Len O, Gavaldà J, Aguado JM, Borrell N, Cervera C, Cisneros JM, Cuervas-Mons V, Gurguí M, Martin-Dávila P, Montejo M, Muñoz P, Bou G, Carratalà J, Torre- Cisneros J, Pahissa A; RESITRA. Valganciclovir as treatment for cytomegalovirus disease in solid organ transplant recipients. Clin Infect Dis. 2008 Jan 1;46(1):20-7. Moreno A, Cervera C, Gavaldá J, Rovira M, de la Cámara R, Jarque I, Montejo M, de la Torre-Cisneros J, Miguel Cisneros J, Fortún J, López-Medrano F, Gurguí M, Muñoz P, Ramos A, Carratalá J. Bloodstream infections among transplant recipients: results of a nationwide surveillance in Spain. Am J Transplant. 2007 Nov;7(11):2579-86. Len O, Gavaldà J, Blanes M, Montejo M, San Juan R, Moreno A, Carratalà J, de la Torre-Cisneros J, Bou G, Cordero E, Muñoz P, Cuervas-Mons V, Alvarez MT, Borrell N, Fortun J, Pahissa A; Spanish Research Network for the Study of Infection in Transplantation. Donor infection and transmission to the recipient of a solid allograft. Am J Transplant. 2008 Nov;8(11):2420-5. San Juan R, Aguado JM, Lumbreras C, Fortun J, Muñoz P, Gavalda J, Lopez- Medrano F, Montejo M, Bou G, Blanes M, Ramos A, Moreno A, Torre-Cisneros J, Carratalá J; RESITRA Network of the Spanish Study Group of Infection in Transplantation. Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation. Clin Infect Dis. 2008 Oct 1;47(7):875-82.

22 RESITRA Aguilar-Guisado M, Givaldá J, Ussetti P, Ramos A, Morales P, Blanes M, Bou G, de la Torre-Cisneros J, Román A, Borro JM, Lama R, Cisneros JM; RESITRA cohort. Pneumonia after lung transplantation in the RESITRA Cohort: a multicenter prospective study. Am J Transplant. 2007 Aug;7(8):1989-96. San Juan R, Aguado JM, Lumbreras C, Díaz-Pedroche C, López-Medrano F, Lizasoain M, Gavalda J, Montejo M, Moreno A, Gurguí M, Torre-Cisneros J; RESITRA Network, Spain,. Incidence, clinical characteristics and risk factors of late infection in solid organ transplant recipients: data from the RESITRA study group. Am J Transplant. 2007 Apr;7(4):964-71. Garrido RS, Aguado JM, Díaz-Pedroche C, Len O, Montejo M, Moreno A, Gurguí M, Torre-Cisneros J, Pareja F, Segovia J, Garcia M, Lumbreras C. A review of critical periods for opportunistic infection in the new transplantation era. Transplantation. 2006 Dec 15;82(11):1457-62. Gavalda J, Len O, San Juan R, Aguado JM, Fortun J, Lumbreras C, Moreno A, Munoz P, Blanes M, Ramos A, Rufi G, Gurgui M, Torre-Cisneros J, Montejo M, Cuenca-Estrella M, Rodriguez-Tudela JL, Pahissa A; RESITRA (Spanish Network for Research on Infection in Transplantation). Risk factors for invasive aspergillosis in solid-organ transplant recipients: a case-control study. Clin Infect Dis. 2005 Jul 1;41(1):52-9.


Download ppt "RESITRA Red de EStudio de la Infección en el TRAsplante Research network for the study of infection in transplantation Dr Jordi Carratala Hospital de Bellvitge."

Similar presentations


Ads by Google