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DNA What are your chances?. DNA Damage Inactive section of DNA strand Gene damage which is reparable Gene damage causing malignancy Gene damage causing.

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Presentation on theme: "DNA What are your chances?. DNA Damage Inactive section of DNA strand Gene damage which is reparable Gene damage causing malignancy Gene damage causing."— Presentation transcript:

1 DNA What are your chances?

2 DNA Damage Inactive section of DNA strand Gene damage which is reparable Gene damage causing malignancy Gene damage causing cell mutation (non reproductive cells) Gene damage causing cell mutation in reproductive cells Gene damage causing cell death Damage to inactive genes Inconsequential gene damage Not all of these are harmful

3 DNA Damage Inactive section of DNA strand Gene damage which is reparable Gene damage causing malignancy Gene damage causing cell mutation (non reproductive cells) Gene damage causing cell mutation in reproductive cells Gene damage causing cell death Damage to inactive genes Inconsequential gene damage

4 The impact if ionizing radiation on DNA can have diverse consequences –None at all –Inconsequential –Serious DNA damage by ionizing radiation is a matter of chance

5 Chances of DNA damage Estimates of the chance of serious DNA damage derived from survivors of Hiroshima and Nagasaki Limited amount of data is open to interpretation –0.08% of population per rem. –0.04% of population per rem. –No damage at low levels –Low levels of radiation might be benefitial

6 Estimate of US cancer deaths from all forms of ionizing radiation 0.04 % of population per rem Annual dose = 350 mrem/yr = 0.35 rem/yr US population = 305 million Estimated number of cancer deaths (per year) from radiation =

7 In Context Current statistics show that approximately 20% of the US population will die of cancer from all causes. This is about 60 million people. Taking the average lifespan to be about 80 years, at 43,000 per year radiation will account for about 43,000 * 80 = 3.4 million of these deaths. That is about 6 % of the total. The remaining cancer deaths are either caused by other types of mutagens (eg chemicals), or from no identifiable cause.

8 Estimate of US cancer deaths from nuclear fuel cycle 0.04 % of population per rem Annual dose = 0.1 mrem/yr = rem/yr US population = 305 million Estimated number of cancer deaths (per year) from the nuclear fuel cycle =

9 Some other US death statistics CauseDeathsYear Driving42, Drowning Bee/wasp stings Sky diving Bungee jumping51992 Firearms (total)28,663 Firearms (accidental)776 Falls13,322 Smoking435,000


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