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NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert.

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Presentation on theme: "NIGMS Award: 1U54GM104944-01A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert."— Presentation transcript:

1 NIGMS Award: 1U54GM A1 Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN Robert D. Langer, MD, MPH Principal Investigator Research Professor of Allied Health Sciences, UNLV Associate Dean for Clinical and Translational Research and Professor of Family Medicine-Las Vegas, UNSOM

2 What is it?  $20 million 5 year NIH Grant under the IDeA Program  Involving 13 universities across the 7 IDeA states in the Mountain West Research Consortium

3 What are the 7 Mountain West states? Alaska Hawaii Idaho Montana Nevada New Mexico Wyoming

4 Support: to foster Clinical and Translational Research (CTR) according to NIH Definitions for Core Resources to facilitate the development of researchers moving into CTR BOOTSTRAP CTR ACROSS THE MOUNTAIN WEST

5 “a rising tide that … … lifts all ships.” We will sink or swim based on the increase in “R-level” translational and clinical research that we achieve across the region over the next 4 years

6 Who is in it?  UNLV [host]  UNR/UNSOM  U. Alaska – Anchorage  U. Alaska – Fairbanks  U. Hawaii – Manoa  Boise State U.  Idaho State U.  U. Idaho  Montana State U.  U. Montana  New Mexico State U.  U. New Mexico  U. Wyoming

7 What will it do?  Provide Pilot Grants of $40,000-$75,000/yr  Support Mini-Sabbatical and Visiting Scholar awards to build collaborations  Provide Mini-Grants for a variety of activities that can help build independent research  Provide infrastructure and services through Key Component Activities

8 Funding preference  Promising Early Career or New Investigators developing clinical or translational research programs  Established Investigators moving from bench to translational or clinical  Projects focused on health issues relevant to the region, including those in rural and vulnerable populations

9 What will it do?  Use an NIH-style approach to applications and funding  Model the processes that clinical and translational investigators need to master to compete successfully for NIH support

10 Key Component Activities (KCAs)  Education, Mentoring & Career Development KCA  Study Design & Biostatistics KCA  Pilot Grant KCA  Administrative KCA, including editorial support, award management, Annual Meeting

11  Education  Mentoring  Study Design  Biostat  Annual Meeting ALL AVAILABLE regardless of whether you’ve received a competitive award from the CTR-IN

12 What will it do? Hold an Annual Meeting to share science, motivate, build collaborations, & conduct study business that will:  rotate across the 13 partner institutions  feature an annual research theme relevant to health in the region  bring together supported investigators, interested researchers from the region, key administrators from partners, external scientists, the regional biostat team, and senior project staff Second Annual Meeting at UNLV June 7 – 11, 2015 free registration, hotel rate ~ $100/night

13 What’s the current status?  Round 1 Pilot Grants:  24 applications, 6 awarded  Round 1A Pilot Grants:  63 applications, 14 awarded  Round 2 Pilot Grants  97 applications, 15 awarded

14 Year 1 (Rounds 1+1A) Pilot Grants Round 1Round 1ATotal Boise State033 Idaho State011 Montana State213 New Mexico State011 U Alaska - Anchorage011 U Alaska - Fairbanks011 U Idaho011 U Montana202 U Nevada Las Vegas134 U Nevada Reno112 U Wyoming

15 What’s the current status?  Round 2 Pilot Grant RFA for 7/1/14 – 6/30/15:  Process moved entirely online  Letters of Intent with Abstacts were due 3/7/14  124 LOIs with Abstracts received  Invitations to submit were provided 3/14/14  Applications were due 4/25/14  Awards were announced 6/26/14^ via the Pilot Grant Application Portal

16 InstitutionLOIsAppsAwards U. Alaska Anchorage841 U. Alaska Fairbanks552 Boise State U.441 Idaho State U.14 2 U. Idaho841 Montana State U.881 U. Montana541 New Mexico State U.982 UNR23172 UNLV30211 U. Wyoming Year 2 Pilot Grant Summary

17 Visiting Scholars  Call for 02 Year open through 11/26/14  Early Career or New Investigator status  $8,000 to $10,000 including 10% indirect  Investigator salary NOT allowed  Earliest start date 03/01/15  Funds must be expended by 06/30/15  Applications submitted online  Total funds available for all awards in 02 Year: $40,000  Anticipate up to 5 Awards  Dependent on quality and budgets of applications received  5 Applications and 5 Awards in the 01 Year  U Montana – to PG Awardee, U Hawaii, UNLV [3] – one to PG Awardee

18 Mini-Sabbaticals  One call for 02 Year -- open through 11/26/14  Mid-Career or Established Investigator status  Up to $20,000 including 10% indirect  Earliest start date 03/01/15  Funds must be expended by 06/30/15  Applications submitted online  Total funds available for all awards in 02 Year: $80,000  Anticipate up to 4 Awards  Dependent on quality of applications received  First offered in the 02 Year

19 Mini-Grants  Two calls for 02 Year – first open through 10/06/14  Preferred uses:  acquisition of pilot data  analysis of existing data with a specific plan to publish  development of an intervention  development of a community-based collaboration  development of a new research collaboration between investigators at two or more institutions within the CTR- IN

20 Mini-Grants  Up to $10,000 direct costs, plus 10% indirect  Investigator salary NOT allowed  Earliest start date 12/01/14  Second call deadline for 02 Year: 01/14/15  Funds must be expended by 06/30/15  Applications submitted online  Total funds available for all awards in 02 Year: $200,000  Anticipate up to 20 Awards  Dependent on quality of applications received  First offered in the 02 Year

21 Round 3 Pilot Grants  One call for 03 Year – RFA end of January 2015  Earliest start date 07/01/15  Funds must be expended by 06/30/16  Applications submitted online

22 PEOPLE!

23 Your First Call … Your Local Concierge

24 Your First Call Once You Decide to Submit a Proposal … Your Local Biostatistician

25 Senior Leadership Administrative Core Bob Langer, UNLV, PI Jim Kenyon, UNR, Proj Coord John Foreyt, UNSOM, Eval Dir Pilot Grants Curtis Noonan, UMT, Director Bill Shuttleworth, UNM, Assoc Dir Education & Mentoring Jillian Inouye, UNLV, Director Bruce Shiramizu, UH, Mentoring Pope Moseley, UNM, Mentoring Pat Alpert, UNLV, Assoc Dir, Educ Merle Kataoki-Yahiro, UH, Educ Craig Molgaard, UMT, Educ Design, Epidemiology, Biostat Pope Moseley, UNM, Director Orrin Myers, UNM, Assoc Dir UNM CTSA: Richard Larson

26 website ctrin.unlv.edu NIGMS Award: 1U54GM A1

27 Admin KCA Robert Langer, MD, MPH, KCA Director Jim Kenyon, PhD, Project Coordinator CRDEB KCA Pope Moseley, MD, KCA Director CTPG KCA Curtis Noonan, PhD, KCA Director William Shuttleworth, PhD, Associate Director Internal Advisory Committee Carolyn Yucha, PhD, Co-Chair Thomas Schwenk, MD, Co-Chair VPRs of all 13 Partner Universities External Advisory Committee William T. Cefalu, MD, Chair Jill G. Joseph, MD, PhD, MPH, Co-Chair +6 other members from outside the region Steering Committee Robert Langer, MD, MPH, Principal Investigator Jim Kenyon, PhD, Project Coordinator, Partners John Foreyt, PhD, Project Coordinator, T&E Rafael Gorospe, MD, PhD, Project Officer Maria Canto, DDS, MS, MPH, Project Scientist Executive Committee PI 2 Project Coordinators 3 [4 with PI] KCA Directors CTSC Coordinator Principal Investigator Robert D. Langer, MD, MPH CREMCaD KCA Jillian Inouye, PhD, KCA Director Tracking & Evaluation Unit John Foreyt, PhD, Project Coordinator Mentoring Unit Bruce Shiramizu, MD, Associate Director Education Unit Patricia Alpert, DrPH, Associate Director Regional Biostatistician Network Mountain West CTR-IN Organizational Structure Governance and Membership UNM CTSC Richard Larson, MD, Coordinator AFFILIATION COLOR CODE UNLV UNR/UNSOM U. New Mexico U. Montana NIH Other partner Institutions Outside the 7 state region Concierge Network U. of Nevada, Las Vegas - Host U. Alaska – Anchorage Montana State U. U. Alaska – Fairbanks U. of Montana U. of Hawaii U. of Nevada, Reno Boise State U. New Mexico State U. Idaho State U. U. of New Mexico U. of Idaho U. of Wyoming


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