Presentation on theme: "Eat healthy, take your vitamins and maybe one day you will grow big and strong like this graduate Bone Growth Time!"— Presentation transcript:
Eat healthy, take your vitamins and maybe one day you will grow big and strong like this graduate Bone Growth Time!
What does endochondral ossification make bone “out of?” 1.A membrane 2.Bone 3.Cartilage 4.Epithelium
What does intramembranous ossification make bone “out of?” 1.A membrane 2.Bone 3.Cartilage 4.Epithelium
Ossification: formation of bone 2 methods: 1. Intramembranous 2. Endochondral
The Major Players Osteoblasts – build bone Osteoclasts – break down bone tissue Osteogenic cells – “highly mitotic” bone stem cells in membranes Osteocytes – mature bone cells in lacunae
I. Intramembranous Ossification End goal: Production of flat bones of skull and most of the clavicle.
When would osteoclasts be activated? 1.When there is too much Ca 2+ in the blood 2.When there is too little Ca 2+ in the blood 3.When Mr. Verdi gets mad
Formation of the Bony Skeleton Week 8 (of pregnancy, not NFL season) fibrous membranes and hyaline cartilage begin to ossify. Intramembranous ossification: development from fibrous membrane Endochondral ossification: development from hyaline cartilage
STEP THREE Woven bone and periosteum form -accumulating osteoid is laid down between embryonic blood, forming random network result is a network of trabeculae. -vascularized mesenchyme condenses on the external surface of the bone and forms periosteum
Step Four Bone collar of compact bone forms and red marrow appears -Trabeculae just deep to the periosteum thicken, forming a bone collar that will later be replaced by mature bone -Spongy bone (diploe in flat bone), persist internally and its vascular tissue becomes red marrow
Summary now! Haiku time Write ~ 3 haikues about intramembranous ossification
Endochondral Ossification Why are the Buckeyes excited?
Fun facts Begins in the second month of development. More complex than intramembranous ossification Begins in the center of long bone (which is made of hyaline cartilage at the time) “primary ossification center”